Recognition mechanism of p63 by the E3 ligase Itch: Novel strategy in the study and inhibition of this interaction

Cell Cycle

Volumn 11, Issue 19, 2012, Pages 3638-3648

  Bellomaria, Alessia ^a   Barbato, Gaetano ^a   Melino, Gerry ^a,b   Paci, Maurizio ^a   Melino, Sonia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Cyclization; E3 ubiquitin ligases; HECT; Metal peptide; P53 family; P63; Ubiquitilation

Indexed keywords

PROTEIN P63; PROTEIN P73; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 ITCH; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; COMPETITIVE INHIBITION; COMPLEX FORMATION; CYCLIZATION; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; HUNTINGTON CHOREA; LIGAND BINDING; METAL BINDING; MOLECULAR RECOGNITION; MUSCULAR DYSTROPHY; OXIDATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STRUCTURE ANALYSIS;

EID: 84867266706     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.21918     Document Type: Article

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