HECT-type ubiquitin ligase ITCH targets Lysosomal-associated Protein Multispanning Transmembrane 5 (LAPTM5) and prevents LAPTM5-mediated cell death

Journal of Biological Chemistry

Volumn 286, Issue 51, 2011, Pages 44086-44094

  Ishihara, Takaya ^a   Inoue, Jun ^a   Kozaki, Ken Ichi ^a   Imoto, Issei ^a   Inazawa, Johji ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTRACELLULAR VESICLES; MEMBRANE PROTEINS; MOLECULAR MECHANISM; NEGATIVE REGULATORS; NEUROBLASTOMA CELLS; NEUROBLASTOMAS; OVER-EXPRESSION; PROGRAMMED CELL DEATHS; TRANSMEMBRANES; UBIQUITIN LIGASES; UBIQUITINATION; WW DOMAIN;

BIOLOGICAL MEMBRANES; CELL DEATH; DEGRADATION;

PROTEINS;

ITCH PROTEIN; LAPTM5 PROTEIN; MEMBRANE PROTEIN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME BINDING; ENZYME SUBSTRATE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MOTIF; PROTEIN STABILITY; REGULATORY MECHANISM; TUMOR REGRESSION; UBIQUITINATION;

CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; MUTATION; NEUROBLASTOMA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 83755162631     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.251694     Document Type: Article

References (24)

1. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
2. Perry, W. L., Hustad, C. M., Swing, D. A., O'Sullivan, T. N., Jenkins, N. A., and Copeland, N. G. (1998) Nat. Genet. 18, 143-146
3. Melino, G., Gallagher, E., Aqeilan, R. I., Knight, R., Peschiaroli, A., Rossi, M., Scialpi, F., Malatesta, M., Zocchi, L., Browne, G., Ciechanover, A., and Bernassola, F. (2008) Cell Death Differ. 15, 1103-1112
4. Ishihara, T., Tsuda, H., Hotta, A., Kozaki, K., Yoshida, A., Noh, J. Y., Ito, K., Imoto, I., and Inazawa, J. (2008) Cancer Sci. 99, 1940-1949
5. Zhang, P., Wang, C., Gao, K., Wang, D., Mao, J., An, J., Xu, C., Wu, D., Yu, H., Liu, J. O., and Yu, L. (2010) J. Biol. Chem. 285, 8869-8879
6. Salah, Z., Melino, G., and Aqeilan, R. I. (2011) Cancer Res. 71, 2010-2020
7. Pak, Y., Glowacka, W. K., Bruce, M. C., Pham, N., and Rotin, D. (2006) J. Cell Biol. 175, 631-645
8. Ouchida, R., Kurosaki, T., and Wang, J. Y. (2010) J. Immunol. 185, 294-301
9. Ouchida, R., Yamasaki, S., Hikida, M., Masuda, K., Kawamura, K., Wada, A., Mochizuki, S., Tagawa, M., Sakamoto, A., Hatano, M., Tokuhisa, T., Koseki, H., Saito, T., Kurosaki, T., and Wang, J. Y. (2008) Immunity 29, 33-43
10. Inoue, J., Misawa, A., Tanaka, Y., Ichinose, S., Sugino, Y., Hosoi, H., Sugimoto, T., Imoto, I., and Inazawa, J. (2009) PLoS One 4, e7099
11. Shimada, Y., Imamura, M., Wagata, T., Yamaguchi, N., and Tobe, T. (1992) Cancer 69, 277-284
12. Matsui, T., Maeda, M., Doi, Y., Yonemura, S., Amano, M., Kaibuchi, K., Tsukita, S., and Tsukita, S. (1998) J. Cell Biol. 140, 647-657
13. Nishida, T., Terashima, M., Fukami, K., and Yamada, Y. (2007) Biochem. J. 405, 481-488
14. Qiu, L., Joazeiro, C., Fang, N., Wang, H. Y., Elly, C., Altman, Y., Fang, D., Hunter, T., and Liu, Y. C. (2000) J. Biol. Chem. 275, 35734-35737
15. Adra, C. N., Zhu, S., Ko, J. L., Guillemot, J. C., Cuervo, A. M., Kobayashi, H., Horiuchi, T., Lelias, J. M., Rowley, J. D., and Lim, B. (1996) Genomics 35, 328-337
16. Boya, P., Andreau, K., Poncet, D., Zamzami, N., Perfettini, J. L., Metivier, D., Ojcius, D. M., Jäättelä, M., and Kroemer, G. (2003) J. Exp. Med. 197, 1323-1334
17. Boya, P., and Kroemer, G. (2008) Oncogene 27, 6434-6451
18. Lévy, F., Muehlethaler, K., Salvi, S., Peitrequin, A. L., Lindholm, C. K., Cerottini, J. C., and Rimoldi, D. (2005) Mol. Biol. Cell 16, 1777-1787
19. Sundvall, M., Korhonen, A., Paatero, I., Gaudio, E., Melino, G., Croce, C. M., Aqeilan, R. I., and Elenius, K. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 4162-4167
20. Marchese, A., Raiborg, C., Santini, F., Keen, J. H., Stenmark, H., and Benovic, J. L. (2003) Dev. Cell 5, 709-722
21. David, R. (2011) Nat. Rev. Mol. Cell Biol. 12, 135
22. Brodeur, G. M. (2003) Nat. Rev. Cancer 3, 203-216
23. Schwab, M., Westermann, F., Hero, B., and Berthold, F. (2003) Lancet Oncol. 4, 472-480
24. Maris, J. M., Hogarty, M. D., Bagatell, R., and Cohn, S. L. (2007) Lancet 369, 2106-2120