-
1
-
-
0002384775
-
Cancer of the lung
-
In: Principles and Practice of Oncology. DeVita VT Jr, Hellman S and Rosenberg SA (eds), Lippincott, Philadelphia
-
Ginsberg RJ, Kris MK and Armstrong JG: Cancer of the lung. In: Principles and Practice of Oncology. DeVita VT Jr, Hellman S and Rosenberg SA (eds). 4th edition. Lippincott, Philadelphia, pp.673-682, 1993.
-
(1993)
4th Edition
, pp. 673-682
-
-
Ginsberg, R.J.1
Kris, M.K.2
Armstrong, J.G.3
-
2
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2009. Ca Cancer J Clin 59: 225-249, 2009.
-
(2009)
Ca Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
3
-
-
6044223545
-
Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers
-
Zhou X, Tan M, Stone Hawthorne V, et al: Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res 10: 6779-6788, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6779-6788
-
-
Zhou, X.1
Tan, M.2
Stone, H.V.3
-
4
-
-
2342559981
-
The TOR pathway: Target for cancer therapy
-
Bjornsti MA and Houghton PJ: The TOR pathway: target for cancer therapy. Nat Rev Cancer 4: 335-348, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
5
-
-
79952495236
-
Mammalian target of rapamycin: Biological function and target for novel anticancer agents
-
Borders EB, Bivona C and Medina PJ: Mammalian target of rapamycin: biological function and target for novel anticancer agents. Am J Health Syst Pharm 67: 2095-2106, 2010.
-
(2010)
Am J Health Syst Pharm
, vol.67
, pp. 2095-2106
-
-
Borders, E.B.1
Bivona, C.2
Medina, P.J.3
-
6
-
-
80051479542
-
Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma
-
Liu D, Huang Y, Chen B, et al: Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma. Cancer 117: 3763-3773, 2011.
-
(2011)
Cancer
, vol.117
, pp. 3763-3773
-
-
Liu, D.1
Huang, Y.2
Chen, B.3
-
7
-
-
84855449478
-
Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: A verification study
-
Gately K, Al-Alao B, Dhillon T, et al: Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: a verification study. Lung Cancer 75: 217-222, 2012.
-
(2012)
Lung Cancer
, vol.75
, pp. 217-222
-
-
Gately, K.1
Al-Alao, B.2
Dhillon, T.3
-
8
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak Y, Peterson TR, Shaul YD, et al: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320: 1496-1501, 2008.
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
-
9
-
-
78549273400
-
Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway
-
Shibata T, Saito S, Kokubu A, et al: Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway. Cancer Res 70: 9095-9105, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 9095-9105
-
-
Shibata, T.1
Saito, S.2
Kokubu, A.3
-
10
-
-
77954695549
-
Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features
-
Solis LM, Behrens C, Dong W, et al: Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. Clin Cancer Res 16: 3743-3753, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3743-3753
-
-
Solis, L.M.1
Behrens, C.2
Dong, W.3
-
11
-
-
77953139490
-
NFE2L2 gene mutation in male Japanese squamous cell carcinoma of the lung
-
Sasaki H, Hikosaka Y, Okuda K, et al: NFE2L2 gene mutation in male Japanese squamous cell carcinoma of the lung. J Thorac Oncol 5: 786-789, 2010.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 786-789
-
-
Sasaki, H.1
Hikosaka, Y.2
Okuda, K.3
-
12
-
-
51649130168
-
Cancer related mutations in Nrf2 impair its recognition by Keap1-Clu3 E3 ligase and promote malignancy
-
Shibata T, Ohta T, Tong KI, et al: Cancer related mutations in Nrf2 impair its recognition by Keap1-Clu3 E3 ligase and promote malignancy. Proc Natl Acad Sci USA 105: 13568-13573, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13568-13573
-
-
Shibata, T.1
Ohta, T.2
Tong, K.I.3
-
13
-
-
84863091925
-
Mutation of the Nrf2 gene in non-small cell lung cancer
-
(Epub ahead of print)
-
Hu Y, Ju Y, Lin D, et al: Mutation of the Nrf2 gene in non-small cell lung cancer. Mol Biol Rep: Oct 1, 2011 (Epub ahead of print).
-
(2011)
Mol Biol Rep: Oct
, pp. 1
-
-
Hu, Y.1
Ju, Y.2
Lin, D.3
-
14
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma XM and Blenis J: Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10: 307-318, 2009.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
15
-
-
48649085816
-
regulation of TORC1 by Rag GTPases in nutrient response
-
Kim E, Goraksha-Hicks P, Li L, et al. regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol 10: 935-945, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
-
16
-
-
0031577292
-
An Nef2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K, Chiba T, Takahashi S, et al: An Nef2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236: 313-322, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
-
17
-
-
0036783335
-
Pharmacogenomics, regulation and signaling pathways of phase I and II detoxifying enzymes
-
Rushmore TH and Kong AN: Pharmacogenomics, regulation and signaling pathways of phase I and II detoxifying enzymes. Curr Drug Metab 3: 481-490, 2002.
-
(2002)
Curr Drug Metab
, vol.3
, pp. 481-490
-
-
Rushmore, T.H.1
Kong, A.N.2
-
18
-
-
3142570440
-
The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
-
Ngyyen T, Yang CS and Pickett CB: The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress. Free Radic Biol Med 37: 433-441, 2004.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 433-441
-
-
Ngyyen, T.1
Yang, C.S.2
Pickett, C.B.3
-
19
-
-
54249087596
-
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
-
Singh A, Boldin-Adamsky S, Thimmulappa RK, et al: RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res 68: 7975-7984, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 7975-7984
-
-
Singh, A.1
Boldin-Adamsky, S.2
Thimmulappa, R.K.3
-
20
-
-
44349189804
-
Nrf2 gene promoter polymorphism and gastric carcinogenesis
-
Arisawa T, Tahara T, Shibata T, et al: Nrf2 gene promoter polymorphism and gastric carcinogenesis. Hepatogastroenterology. 55: 750-754, 2008.
-
(2008)
Hepatogastroenterology
, vol.55
, pp. 750-754
-
-
Arisawa, T.1
Tahara, T.2
Shibata, T.3
-
21
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL: Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 3: 721-732, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
23
-
-
84866629688
-
mTOR and PTEN expression in non-small cell lung cancer: Analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistry
-
Nov 30, (Epub ahead of print)
-
Wang L, Yue W, Zhang L, et al: mTOR and PTEN expression in non-small cell lung cancer: analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistry. Surg Today: Nov 30, 2011 (Epub ahead of print).
-
(2011)
Surg Today
-
-
Wang, L.1
Yue, W.2
Zhang, L.3
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