Fomitoside-K from Fomitopsis nigra induces apoptosis of human oral squamous cell carcinomas (YD-10B) via mitochondrial signaling pathway

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 10, 2012, Pages 1711-1719

  Bhattarai, Govinda ^a   Lee, Young Hee ^a   Lee, Nan Hee ^a   Lee, In Kyoung ^a   Yun, Bong Sik ^a   Hwang, Pyong Han ^a   Yi, Ho Keun ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Anti cancer drug; Apoptosis; Cytochrome c; Fomitoside K; Oral squamous cell carcinoma; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; ADENOSINE DIPHOSPHATE RIBOSE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOCHROME C; DOXORUBICIN; FOMITOSIDE K EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SCAVENGER; STRESS ACTIVATED PROTEIN KINASE; SURVIVIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL DEATH; CELL STRUCTURE; CYTOSOL; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; FOMITOPSIS NIGRA; HUMAN; HUMAN CELL; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUTH SQUAMOUS CELL CARCINOMA; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL PROLIFERATION; CORIOLACEAE; CYCLIN D1; CYTOCHROMES C; GLYCOSIDES; HUMANS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MOUTH NEOPLASMS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 84867251514     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00297     Document Type: Article

References (31)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics, 2008. CA Cancer J. Clin., 58, 71-96 (2008).
2. Shin HK, Kim J, Lee EJ, Kim SH. Inhibitory effect of curcumin on motility of human oral squamous carcinoma YD-10B cells via suppression of ERK and NF-κB activations. Phytother. Res., 24, 577-582 (2010).
3. Venkateshwar RG, Kumar S, Islam M, Mansour SE. Folk medicines for anticancer therapy - a current status. Cancer Therapy, 6, 913-922 (2008).
4. Das SK, Masuda M, Sakurai A, Sakakibara M. Medicinal uses of the mushroom Cordyceps militaris: current state and prospects. Fitoterapia, 81, 961-968 (2010).
5. Lee IK, Jung JY, Yeom JH, Ki DW, Lee MS, Yeo WH, Yun BS. Fomitoside K, a new lanostane triterpene glycoside from the fruiting body of Fomitopsis nigra. Mycobiology, 40, 76-78 (2012).
6. Kroemer G, Petit P, Zamzami N, Vayssière JL, Mignotte B. The biochemistry of programmed cell death. FASEB J., 9, 1277-1287 (1995).
7. Hou DX, Tong XH, Terahara N, Luo D, Fujii M. Delphinidin 3-sambubioside, a Hibiscus anthocyanin, induces apoptosis in human leukemia cells through reactive oxygen species-mediated mitochondrial pathway. Arch. Biochem. Biophys., 440, 101-109 (2005).
8. Chipuk JE, Bouchier-Hayes L, Green DR. Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ., 13, 1396-1402 (2006).
9. Ricci JE, Gottlieb RA, Green DR. Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J. Cell Biol., 160, 65-75 (2003).
10. Zhao Q, Cao X, Zeng B, Wang C, Yan L, Xu C. Musca domestica larva lectin induces apoptosis in BEL-7402 cells through a mitochondria- mediated reactive oxygen species way. Biol. Pharm. Bull., 33, 1274-1278 (2010).
11. Collins L, Zhu T, Guo J, Xiao ZJ, Chen CY. Phellinus linteus sensitises apoptosis induced by doxorubicin in prostate cancer. Br. J. Cancer, 95, 282-288 (2006).
12. Hsieh YC, Rao YK, Whang-Peng J, Huang CY, Shyue SK, Hsu SL, Tzeng YM. Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway. J. Agric. Food Chem., 59, 10943-10954 (2011).
13. Bhattarai G, Lee YH, Lee NH, Yun JS, Hwang PH, Yi HK. c-myb mediates inflammatory reaction against oxidative stress in human breast cancer cell line, MCF-7. Cell Biochem. Funct., 29, 686-693 (2011).
14. Lee YH, Lee JC, Moon HJ, Jung JE, Sharma M, Park BH, Yi HK, Jhee EC. Differential effect of oxidative stress on the apoptosis of early and late passage human diploid fibroblasts: implication of heat shock protein 60. Cell Biochem. Funct., 26, 502-508 (2008).
15. Javvadi P, Segan AT, Tuttle SW, Koumenis C. The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol. Pharmacol., 73, 1491-1501 (2008).
16. Chen T, Wong YS. Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation. J. Agric. Food Chem., 56, 10574-10581 (2008).
17. Lee SH, Hwang HS, Yun JW. Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT-29 human colon cancer cells. Phytother. Res., 23, 1784-1789 (2009).
18. Russo A, Cardile V, De Ioannes A, Garbarino J. Effect of litreol on the viability of human cancer cells. Chem. Biol. Interact., 179, 178-184 (2009).
19. Singh RP, Dhanalakshmi S, Agarwal R. Phytochemicals as cell cycle modulators - a less toxic approach in halting human cancers. Cell Cycle, 1, 156-161 (2002).
20. Tong X, Lin S, Fujii M, Hou DX. Echinocystic acid induces apoptosis in HL-60 cells through mitochondria-mediated death pathway. Cancer Lett., 212, 21-32 (2004).
21. Kim R, Tanabe K, Uchida Y, Emi M, Inoue H, Toge T. Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy. Cancer Chemother. Pharmacol., 50, 343-352 (2002).
22. Armstrong JS. Mitochondria: a target for cancer therapy. Br. J. Pharmacol., 147, 239-248 (2006).
23. Camins A, Pallas M, Silvestre JS. Apoptotic mechanisms involved in neurodegenerative diseases: experimental and therapeutic approaches. Methods Find. Exp. Clin. Pharmacol., 30, 43-65 (2008).
24. Altieri DC. Survivin, cancer networks and pathway-directed drug discovery. Nat. Rev. Cancer, 8, 61-70 (2008).
25. Jing Y, Yang J, Wang Y, Li H, Chen Y, Hu Q, Shi G, Tang X, Yi J. Alteration of subcellular redox equilibrium and the consequent oxidative modification of nuclear factor kappaB are critical for anticancer cytotoxicity by emodin, a reactive oxygen species-producing agent. Free Radic. Biol. Med., 40, 2183-2197 (2006).
26. Javvadi P, Segan AT, Tuttle SW, Koumenis C. The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol. Pharmacol., 73, 1491-1501 (2008).
27. Zu K, Hawthorn L, Ip C. Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells. Mol. Cancer Ther., 4, 43-50 (2005).
28. Ma Y, Yu WD, Kong RX, Trump DL, Johnson CS. Role of nongenomic activation of phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase 1/2 pathways in 1,25D3-mediated apoptosis in squamous cell carcinoma cells. Cancer Res., 66, 8131-8138 (2006).
29. Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, Keum YS, Nair S, Kong AN. ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. Carcinogenesis, 27, 437-445 (2006).
30. Adhami VM, Malik A, Zaman N, Sarfaraz S, Siddiqui IA, Syed DN, Afaq F, Pasha FS, Saleem M, Mukhtar H. Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo. Clin. Cancer Res., 13, 1611-1619 (2007).
31. Khor TO, Keum YS, Lin W, Kim JH, Hu R, Shen G, Xu C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Res., 66, 613-621 (2006).