Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 20, 2011, Pages 10943-10954

  Hsieh, Yun Chih ^a   Rao, Yerra Koteswara ^b   Whang Peng, Jacqueline ^c   Huang, Chi Ying F ^d   Shyue, Song Kun ^e   Hsu, Shih Lan ^a   Tzeng, Yew Min ^b  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHAOYANG UNIVERSITY OF TECHNOLOGY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

^e INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

antcin B; extrinsic and intrinsic apoptosis; hepatocellular carcinoma cells; methylantcinate B; oxidative stress

Indexed keywords

ANTCIN B; ANTIOXIDANT ENZYME; ANTRODIA CAMPHORATA; APOPTOSIS PATHWAYS; APOPTOTIC EFFECTS; APOPTOTIC PATHWAYS; APOPTOTIC PROCESS; ASCORBIC ACIDS; CANCER CELLS; CASPASES; CELL VIABILITY; CHROMATIN CONDENSATION; CYTOTOXIC AGENTS; DNA DAMAGES; DNA FRAGMENTATION; ESTER DERIVATIVES; FAS LIGAND; HEPATOCELLULAR CARCINOMA; HEPATOCELLULAR CARCINOMA CELL; HEPG2 CELLS; INDUCED APOPTOSIS; MEDICINAL MUSHROOM; METHYLANTCINATE B; MITOCHONDRIAL MEMBRANE POTENTIAL; N-ACETYLCYSTEINE; NADPH OXIDASE; PROTEIN LEVEL; REACTIVE OXYGEN SPECIES; SUPER OXIDE DISMUTASE; TRITERPENOIDS;

CELL MEMBRANES; CYTOTOXICITY; DRUG PRODUCTS; KETONES; MITOCHONDRIA; ORGANIC ACIDS; OXIDATIVE STRESS; OXYGEN;

CELL DEATH;

ANTCIN B; ANTINEOPLASTIC AGENT; CHOLEST 4 EN 3 ONE; METHYL ANTICINATE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANTRODIA; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; OXIDATIVE STRESS; PATHOLOGY;

ANTINEOPLASTIC AGENTS; ANTRODIA; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CHOLESTENONES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

BASIDIOMYCOTA; TAIWANOFUNGUS CAMPHORATUS;

EID: 80054984329     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf202771d     Document Type: Article

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