Girdin locates in centrosome and midbody and plays an important role in cell division

Cancer Science

Volumn 103, Issue 10, 2012, Pages 1780-1787

  Mao, Jing Zhuo ^a   Jiang, Ping ^a   Cui, Su Ping ^a,b   Ren, Ya Li ^c   Zhao, Jing ^a   Yin, Xiu Hua ^d   Enomoto, Atsushi ^e   Liu, Hai Jing ^a   Hou, Lin ^a   Takahashi, Masahide ^e   Zhang, Bo ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING HOSPITAL   (China)

^c PEKING UNIVERSITY FIRST HOSPITAL   (China)

^d Department of Oncology   (China)

^e NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL CYCLE PROTEIN; PROTEIN GIRDIN; PROTEIN KINASE B; REGULATOR PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CELL DIVISION; CELL EXPANSION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE REPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOCOMPROMISED PATIENT; IN VIVO STUDY; MICROTUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RETROVIRUS INFECTION; TUMOR GROWTH;

ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CENTROSOME; CYTOSKELETON; FEMALE; HELA CELLS; HUMANS; MICE; MICE, NUDE; MICROFILAMENT PROTEINS; TRANSFECTION; VESICULAR TRANSPORT PROTEINS;

EID: 84867232587     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2012.02378.x     Document Type: Article

References (46)

1. Rodriguez OC, Schaefer AW, Mandato CA, Forscher P, Bement WM, Waterman-Storer CM. Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat Cell Biol 2003; 5: 599-609.
2. Kunda P, Baum B. The actin cytoskeleton in spindle assembly and positioning. Trends Cell Biol 2009; 19: 174-9.
3. Von-Dassow G. Concurrent cues for cytokinetic furrow induction in animal cells. Trends Cell Biol 2009; 19: 165-73.
4. Steigemann P, Gerlich DW. Cytokinetic abscission: cellular dynamics at the midbody. Trends Cell Biol 2009; 19: 606-16.
5. Cao J, Crest J, Fasulo B, Sullivan W. Cortical actin dynamics facilitate early-stage centrosome separation. Curr Biol 2010; 27: 770-6.
6. Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006; 7: 505-16.
7. Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005; 5: 341-54.
8. Gonzalez-Perez O, Quiñones-Hinojosa A. Dose-dependent effect of EGF on migration and differentiation of adult subventricular zone astrocytes. Glia 2010; 58: 975-83.
9. Yang X, Zhu MJ, Sreejayan N, Ren J, Du M. Angiotensin II promotes smooth muscle cell proliferation and migration through release of heparin-binding epidermal growth factor and activation of EGF-receptor pathway. Mol Cells 2005; 20: 263-70.
10. Andl CD, Mizushima T, Nakagawa H et al. Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo. J Biol Chem 2003; 278: 1824-30.
11. Boulay PL, Cotton M, Melancon P, Claing A. ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J Biol Chem 2008; 283: 36425-34.
12. Wang Z, Sengupta R, Banerjee S et al. Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. Cancer Res 2006; 66: 7653-60.
13. Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007; 129: 1261-74.
14. Shin I, Yakes FM, Rojo F et al. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 2002; 8: 1145-52.
15. Jiang BH, Liu LZ. Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment. Drug Resist Updat 2008; 11: 63-76.
16. Gao D, Inuzuka H, Tseng A, Wei W. Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. Cell Div 2009; 4: 11.
17. Feigin ME, Muthuswamy SK. ErbB receptors and cell polarity: new pathways and paradigms for understanding cell migration and invasion. Exp Cell Res 2009; 315: 707-16.
18. Buttrick GJ, Wakefield JG. PI3-K and GSK-3 Akt-ing together with microtubules. Cell Cycle 2008; 7: 2621-5.
19. Amiri A, Noei F, Jeganathan S, Kulkarni G, Pinke DE, Lee JM. eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration. Oncogene 2007; 26: 3027-40.
20. Kharchenko MV, Aksyonov AA, Melikova MM, Kornilova ES. Epidermal growth factor (EGF) receptor endocytosis is accompanied by reorganization of microtubule system in HeLa cells. Cell Biol Int 2007; 31: 349-59.
21. Enomoto A, Ping J, Takahashi M. Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways. Ann N Y Acad Sci 2006; 1086: 169-84.
22. Simpson F, Martin S, Evans TM et al. A novel hook-related protein family and the characterization of hook-related protein 1. Traffic 2005; 6: 442-58.
23. Enomoto A, Murakami H, Asai N et al. Akt/PKB regulates actin organization and cell motility via Girdin/APE. Dev Cell 2005; 9: 389-402.
24. Weng L, Enomoto A, Ishida-Takagishi M, Asai N, Takahashi M. Girding for migratory cues: roles of the Akt substrate Girdin in cancer progression and angiogenesis. Cancer Sci 2010; 101: 836-42.
25. Jiang P, Enomoto A, Jijiwa M et al. An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer Res 2008; 68: 1310-8.
26. Le-Niculescu H, Niesman I, Fischer T, DeVries L, Farquhar MG. Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles. J Biol Chem 2005; 280: 22012-20.
27. Garcia-Marcos M, Ghosh P, Farquhar MG. GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling. Proc Natl Acad Sci U S A 2009; 106: 3178-83.
28. Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG. Activation of Galphai3 triggers cell migration via regulation of GIV. J Cell Biol 2008; 182: 381-93.
29. Ghosh P, Beas AO, Bornheimer SJ et al. A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate. Mol Biol Cell 2010; 21: 2338-54.
30. Anai M, Shojima N, Katagiri H et al. A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. J Biol Chem 2005; 280: 18525-35.
31. Ariyoshi W, Takahashi T, Kanno T et al. Heparin inhibits osteoclastic differentiation and function. J Cell Biochem 2008; 103: 1707-17.
32. Cho H, Kehrl JH. Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division. J Cell Biol 2007; 178: 245-55.
33. Barr FA, Gruneberg U. Cytokinesis: placing and making the final cut. Cell 2007; 131: 847-60.
34. Zyss D, Gergely F. Centrosome function in cancer: guilty or innocent? Trends Cell Biol 2009; 19: 334-46.
35. Fukasawa K. Oncogenes and tumour suppressors take on centrosomes. Nat Rev Cancer 2007; 7: 911-24.
36. Zhang R, Burke LJ, Rasko JE, Lobanenkov V, Renkawitz R. Dynamic association of the mammalian insulator protein CTCF with centrosomes and the midbody. Exp Cell Res 2004; 294: 86-93.
37. Morin P, Flors C, Olson MF. Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis. Eur J Cell Biol 2009; 88: 495-507.
38. Otegui MS, Verbrugghe KJ, Skop AR. Midbodies and phragmoplasts: analogous structures involved in cytokinesis. Trends Cell Biol 2005; 15: 404-13.
39. Thompson HM, Skop AR, Euteneuer U, Meyer BJ, McNiven MA. The large GTPase dynamin associates with the spindle midzone and is required for cytokinesis. Curr Biol 2002; 12: 2111-7.
40. Sherline P, Mascardo R. Epidermal growth factor-induced centrosomal separation: mechanism and relationship to mitogenesis. J Cell Biol 1982; 95: 316-22.
41. Wakefield JG, Stephens DJ, Tavaré JM. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J Cell Sci 2003; 116(Pt 4): 637-46.
42. Buttrick GJ, Beaumont LM, Leitch J, Yau C, Hughes JR, Wakefield JG. Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo. J Cell Biol 2008; 180: 537-48.
43. Plo I, Lopez B. AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells. Oncogene 2009; 28: 2231-7.
44. Liu X, Shi Y, Woods KW et al. Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression. Neoplasia 2008; 10: 828-37.
45. Janetopoulos C, Borleis J, Vazquez F, Iijima M, Devreotes P. Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis. Dev Cell 2005; 8: 467-77.
46. Celton-Morizur S, Merlen G, Couton D, Margall-Ducos G, Desdouets C. The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents. J Clin Invest 2009; 119: 1880-7.