Aging in the mouse and perspectives of rejuvenation through induced pluripotent stem cells (iPSCs)

Results and Problems in Cell Differentiation

Volumn 55, Issue , 2012, Pages 413-427

  Isobe, Ken Ichi ^a   Cheng, Zhao ^a   Ito, Sachiko ^a   Nishio, Naomi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84867224220     PISSN: 00801844     EISSN: 18610412     Source Type: Book Series    
DOI: 10.1007/978-3-642-30406-4_21     Document Type: Article

References (67)

1. Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I, et al. (2009) Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev 23(18):2134-2139
2. Blasco MA (2007) The epigenetic regulation of mammalian telomeres. Nat Rev Genet 8(4):299-309
3. Blau HM, Pavlath GK, Hardeman EC, Chiu CP, Silberstein L, Webster SG, et al. (1985) Plasticity of the differentiated state. Science 230(4727):758-766
4. Boguski MS (2002) Comparative genomics: the mouse that roared. Nature 420(6915):515-516
5. Cheng Z, Ito S, Nishio N, Xiao H, Zhang R, Suzuki H, et al. (2011) Establishment of induced pluripotent stem cells from aged mice using bone marrow-derived myeloid cells. J Mol Cell Biol 3(2):91-98
6. Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, et al. (2009) Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet 5(8):e1000602
7. Dimos JT, Rodolfa KT, Niakan KK, Weisenthal LM, Mitsumoto H, ChungWet al (2008) Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321(5893):1218-1221
8. Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819):154-156
9. Flores I, Benetti R, Blasco MA (2006) Telomerase regulation and stem cell behaviour. Curr Opin Cell Biol 18(3):254-260
10. Gaspar-Maia A, Alajem A, Meshorer E, Ramalho-Santos M (2011) Open chromatin in pluripotency and reprogramming. Nat Rev Mol Cell Biol 12(1):36-47
11. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, et al. (2011) Somatic coding mutations in human induced pluripotent stem cells. Nature 471(7336):63-67
12. Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, et al. (2010) Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature 466(7304):383-387
13. Gurdon JB (1962) The transplantation of nuclei between two species of Xenopus. Dev Biol 5:68-83
14. Gurdon JB, Melton DA (2008) Nuclear reprogramming in cells. Science 322(5909):1811-1815
15. Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345(6274):458-460
16. Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M, et al. (2010) Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 6(5):479-491
17. Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37:614-636
18. Herskind AM, McGue M, Holm NV, Sørensen TI, Harvald B, Vaupel JW (1996) The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900. Hum Genet 97(3):319-323
19. Hogan BL (1976) Changes in the behaviour of teratocarcinoma cells cultivated in vitro. Nature 263(5573):136-137
20. Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, et al. (2009) Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460(7259):1132-1135
21. Hussein SM, Batada NN, Vuoristo S, Ching RW, Autio R, Narva E, et al. (2011) Copy number variation and selection during reprogramming to pluripotency. Nature 471(7336):58-62
22. Jaenisch R, Young R (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132(4):567-582
23. Kanatsu-Shinohara M, Inoue K, Lee J, Yoshimoto M, Ogonuki N, Miki H, et al. (2004) Generation of pluripotent stem cells from neonatal mouse testis. Cell 119(7):1001-1012
24. Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, Raya A, et al. (2009) Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460(7259):1140-1144
25. Kishigami S, Wakayama S, Hosoi Y, Iritani A, Wakayama T (2008) Somatic cell nuclear transfer: infinite reproduction of a unique diploid genome. Exp Cell Res 314(9):1945-1950
26. Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, et al. (2011) Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8(2):200-213
27. Lanza RP, Cibelli JB, Blackwell C, Cristofalo VJ, Francis MK, Baerlocher GM, et al. (2000) Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 288(5466):665-669
28. Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A, Morey R, et al. (2011) Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell 8(1):106-118
29. Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, et al. (2009) The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460(7259):1136-1139
30. Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, et al. (2011) Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 471(7336):68-73
31. Loh YH, Zhang W, Chen X, George J, Ng HH (2007) Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 21(20):2545-2557
32. Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, et al. (2008) Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci USA 105 (8):2883-2888
33. Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, et al. (2010) Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res 20(3):332-340
34. Manosalva I, González A (2010) Aging changes the chromatin configuration and histone methylation of mouse oocytes at germinal vesicle stage. Theriogenology 74(9):1539-1547
35. Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, et al. (2009) A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 460 (7259):1149-1153
36. Martin GM, Sprague CA, Epstein CJ (1970) Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab Invest 23(1):86-92
37. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, et al. (2010) Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 7(4):521-531
38. Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, et al. (2008) Dissecting direct reprogramming through integrative genomic analysis. Nature 454(7200):49-55
39. Mitchell BD, Hsueh WC, King TM, Pollin TI, Sorkin J, Agarwala R, et al. (2001) Heritability of life span in the Old Order Amish. Am J Med Genet 102(4):346-352
40. Mizutani E, Ono T, Li C, Maki-Suetsugu R, Wakayama T (2008) Propagation of senescent mice using nuclear transfer embryonic stem cell lines. Genesis 46(9):478-483
41. Nishio N, Okawa Y, Sakurai H, Isobe K (2008) Neutrophil depletion delays wound repair in aged mice. Age (Dordr) 30(1):11-19
42. Oeppen J, Vaupel JW (2002) Demography. Broken limits to life expectancy. Science 296 (5570):1029-1031
43. Ogonuki N, Inoue K, Yamamoto Y, Noguchi Y, Tanemura K, Suzuki O, et al. (2002) Early death of mice cloned from somatic cells. Nat Genet 30(3):253-254
44. Paigen K. (1995) A miracle enough the power of mice. Nat Med 1:215-220
45. Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, et al. (2008) Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451(7175):141-146
46. Peters LL, Robledo RF, Bult CJ, Churchill GA, Paigen BJ, Svenson KL (2007) The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet 8(1):58-69
47. Rando TA (2006) Stem cells, ageing and the quest for immortality. Nature 441(7097):1080-1086
48. Rohme D (1981) Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc Natl Acad Sci USA 78(8):5009-5013
49. Shiels PG, Kind AJ, Campbell KH, Waddington D, Wilmut I, Colman A, et al. (1999) Analysis of telomere lengths in cloned sheep. Nature 399(6734):316-317
50. Stadtfeld M, Maherali N, Breault DT, Hochedlinger K (2008) Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2(3):230-240
51. Surani MA (1999) Reprogramming a somatic nucleus by trans-modification activity in germ cells. Semin Cell Dev Biol 10(3):273-277
52. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131(5):861-872
53. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663-676
54. Tamashiro KL, Wakayama T, Yamazaki Y, Akutsu H, Woods SC, Kondo S, et al. (2003) Phenotype of cloned mice: development, behavior, and physiology. Exp Biol Med (Maywood) 228 (10):1193-1200
55. Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RM, et al. (2009) Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460(7259):1145-1148
56. vB Hjelmborg J, Iachine I, Skytthe A, Vaupel JW, McGue M, Koskenvuo M, et al. (2006) Genetic influence on human lifespan and longevity. Hum Genet 119(3):312-321
57. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R (1998) Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394(6691):369-374
58. Wakayama T, Shinkai Y, Tamashiro KL, Niida H, Blanchard DC, Blanchard RJ, et al. (2000) Cloning of mice to six generations. Nature 407(6802):318-319
59. Wang C, Jurk D, Maddick M, Nelson G, Martin-Ruiz C, von Zglinicki T (2009) DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 8(3):311-323
60. Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448(7151):318-324
61. Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J, et al. (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473 (7347):343-348
62. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385(6619):810-813
63. Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K, et al. (2011) Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev 25(7):679-684
64. Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, et al. (2008) The ground state of embryonic stem cell self-renewal. Nature 453(7194):519-523
65. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858):1917-1920
66. Yuan R, Peters LL, Paigen B (2011) Mice as a mammalian model for research on the genetics of aging. ILAR J 52(1):4-15
67. Zhao T, Zhang ZN, Rong Z, Xu Y (2011) Immunogenicity of induced pluripotent stem cells. Nature 474(7350):212-215