Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: Thiol reactivity and its implications

Chemico-Biological Interactions

Volumn 200, Issue 1, 2012, Pages 28-37

  Crampsie, Melissa A ^a   Pandey, Manoj K ^a   Desai, Dhimant ^a   Spallholz, Julian ^b   Amin, Shantu ^a   Sharma, Arun K ^a  

^a PENN STATE CANCER INSTITUTE   (United States)

^b TEXAS TECH UNIVERSITY   (United States)

Author keywords

Chemiluminesence; Isoselenocyanates; Isothiocyanates; Redox cycling; ROS; Thiol reactivity

Indexed keywords

ANTINEOPLASTIC AGENT; GLUTATHIONE; ISOTHIOCYANIC ACID DERIVATIVE; PHENYLALKYL ISOSELENOCYANATE DERIVATVE; PHENYLALKYL ISOTHIOCYANATE DERIVATVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; THIOL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ADENOCARCINOMA; OXIDATION REDUCTION REACTION; PROTEIN DEPLETION; PROTEIN MODIFICATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CYANATES; DOWN-REGULATION; GLUTATHIONE; HUMANS; METABOLIC DETOXICATION, PHASE II; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; SELENIUM COMPOUNDS; SULFHYDRYL COMPOUNDS; THIOCYANATES; TRANSCRIPTION, GENETIC;

EID: 84867218755     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.08.022     Document Type: Article

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