Phenylbutyl isoselenocyanate modulates phase I and II enzymes and inhibits 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone-induced DNA adducts in mice

Cancer Prevention Research

Volumn 4, Issue 11, 2011, Pages 1884-1894

  Crampsie, Melissa A ^a   Jones, Nathan ^a   Das, Arunangshu ^a,b   Aliaga, Cesar ^a,b   Desai, Dhimant ^a   Lazarus, Philip ^a,b   Amin, Shantu ^a   Sharma, Arun K ^a  

^a PENN STATE CANCER INSTITUTE   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ANTINEOPLASTIC AGENT; CYANIC ACID DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 2A4; CYTOCHROME P450 2C29; CYTOCHROME P450 2F2; CYTOCHROME P450 2S1; CYTOCHROME P450 3A11; CYTOCHROME P450 4B1; CYTOCHROME P450 8B1; DNA; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A5; GLUCURONOSYLTRANSFERASE 1A6A; GLUCURONOSYLTRANSFERASE 2A3; GLUCURONOSYLTRANSFERASE 2B1; GLUCURONOSYLTRANSFERASE 2B34; GLUCURONOSYLTRANSFERASE 2B5; GLUTATHIONE TRANSFERASE A3; GLUTATHIONE TRANSFERASE A4; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE M2; GLUTATHIONE TRANSFERASE M3; GLUTATHIONE TRANSFERASE P1; MESSENGER RNA; PHENYLBUTYL ISOSELENOCYANATE; SELENIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD LEVEL; CANCER PREVENTION; CARCINOGEN DNA INTERACTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA ADDUCT; DOSE TIME EFFECT RELATION; DRUG BIOAVAILABILITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FEMALE; GENE EXPRESSION REGULATION; LIVER LEVEL; LIVER MICROSOME; LUNG; LUNG CANCER; LUNG MICROSOME; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TISSUE LEVEL;

ADMINISTRATION, ORAL; ANIMALS; BLOTTING, WESTERN; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; DNA ADDUCTS; FEMALE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; LUNG; MICE; MICE, INBRED A; MICROSOMES, LIVER; NITROSAMINES; ORGANOSELENIUM COMPOUNDS; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 81555222611     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-11-0221     Document Type: Article

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