Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells

Archives of Pharmacal Research

Volumn 31, Issue 12, 2008, Pages 1604-1612

  Lee, Ji Won ^a   Cho, Min Kyung ^a  

^a Dongguk University   (South Korea)

Author keywords

Apoptosis; Bcl 2 XIAP; Breast cancer; Mitochondrial pathway; Phenethyl isothiocyanates

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 7; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; DNA FRAGMENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PHENETHYL ISOTHIOCYANATE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; NICK END LABELING;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; DOWN-REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; GENES, BCL-2; GENES, P53; HUMANS; IN SITU NICK-END LABELING; ISOTHIOCYANATES; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 58449110311     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-2158-2     Document Type: Article

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