Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell-independent protective immunity

Journal of Gene Medicine

Volumn 12, Issue 8, 2010, Pages 693-704

  Mu, Jingyu ^a   Jeyanathan, Mangalakumari ^a   Shaler, Christopher R ^a   Horvath, Carly ^a   Damjanovic, Daniela ^a   Zganiacz, Anna ^a   Kugathasan, Kapilan ^a   McCormick, Sarah ^a   Xing, Zhou ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Adenovirus vector; CD4 T cells; CD8 T cells; Lung gene transfer; Mucosal immunity

Indexed keywords

ADENOVIRUS VECTOR; GAMMA INTERFERON; MYCOBACTERIUM ANTIGEN; MYCOBACTERIUM TUBERCULOSIS ANTIGEN AG85A; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE PRODUCTION; DRUG EFFECT; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE TRANSFER; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; LUNG; LUNG TUBERCULOSIS; MOUSE; MUCOSAL IMMUNITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; VACCINATION; VIRAL GENE DELIVERY SYSTEM; VIRUS REPLICATION;

ACYLTRANSFERASES; ADENOVIRIDAE; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY TESTS, IMMUNOLOGIC; FEMALE; GENETIC VECTORS; IMMUNIZATION; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; RESPIRATORY MUCOSA; T-LYMPHOCYTES, HELPER-INDUCER; TUBERCULOSIS VACCINES;

ADENOVIRIDAE; ANIMALIA; MUS; MYCOBACTERIUM TUBERCULOSIS;

EID: 77956624986     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1487     Document Type: Article

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