메뉴 건너뛰기




Volumn 59, Issue 2, 2004, Pages 133-137

Development of an in vitro blood-brain barrier model based on immortalized porcine brain microvascular endothelial cells

Author keywords

Benzodiazepines; Blood brain barrier; Immortalized porcine brain microvascular endothelial cells; In vitro model

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CLOBAZAM; DIAZEPAM; NORCLOBAZAM;

EID: 1042302113     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2003.11.007     Document Type: Article
Times cited : (27)

References (30)
  • 1
    • 0002370144 scopus 로고    scopus 로고
    • Blood-brain barrier methodology and biology
    • Pardridge W.M. Cambridge: Cambridge University Press
    • Pardridge W.M. Blood-brain barrier methodology and biology. Pardridge W.M. Introduction to the Blood-Brain Barrier. 1998;1-8 Cambridge University Press, Cambridge.
    • (1998) Introduction to the Blood-Brain Barrier , pp. 1-8
    • Pardridge, W.M.1
  • 2
    • 0029943119 scopus 로고    scopus 로고
    • Endothelial cells of the brain and other organ systems: Some similarities and differences
    • Joo F. Endothelial cells of the brain and other organ systems: some similarities and differences. Prog. Neurobiol. 48:1996;255-273.
    • (1996) Prog. Neurobiol , vol.48 , pp. 255-273
    • Joo, F.1
  • 3
    • 0021020420 scopus 로고
    • Brain metabolism: A perspective from the blood-brain barrier
    • Pardridge W.M. Brain metabolism: a perspective from the blood-brain barrier. Physiol. Rev. 63:1983;1481-1535.
    • (1983) Physiol. Rev , vol.63 , pp. 1481-1535
    • Pardridge, W.M.1
  • 4
    • 0034821939 scopus 로고    scopus 로고
    • Role of transport proteins in drug absorption, distribution and excretion
    • Ayrton A., Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica. 31:2001;469-497.
    • (2001) Xenobiotica , vol.31 , pp. 469-497
    • Ayrton, A.1    Morgan, P.2
  • 5
    • 0033526179 scopus 로고    scopus 로고
    • Carrier-mediated or specialized transport of drugs across the blood-brain barrier
    • Tsuji A., Tamai I. Carrier-mediated or specialized transport of drugs across the blood-brain barrier. Adv. Drug Deliv. Rev. 36:1999;277-290.
    • (1999) Adv. Drug Deliv. Rev , vol.36 , pp. 277-290
    • Tsuji, A.1    Tamai, I.2
  • 6
    • 0029035114 scopus 로고
    • Transport of small molecules through the blood-brain barrier: Biology and methodology
    • Pardridge W.M. Transport of small molecules through the blood-brain barrier: biology and methodology. Adv. Drug Deliv. Rev. 15:1995;5-36.
    • (1995) Adv. Drug Deliv. Rev , vol.15 , pp. 5-36
    • Pardridge, W.M.1
  • 7
    • 0030580946 scopus 로고    scopus 로고
    • Drug delivery through the blood-brain barrier
    • Tamai I., Tsuji A. Drug delivery through the blood-brain barrier. Adv. Drug Deliv. Rev. 19:1996;401-424.
    • (1996) Adv. Drug Deliv. Rev , vol.19 , pp. 401-424
    • Tamai, I.1    Tsuji, A.2
  • 8
    • 0343247810 scopus 로고    scopus 로고
    • Blood-brain barrier function of P-glycoprotein
    • Tsuji A., Tamai I. Blood-brain barrier function of P-glycoprotein. Adv. Drug Deliv. Rev. 25:1997;287-298.
    • (1997) Adv. Drug Deliv. Rev , vol.25 , pp. 287-298
    • Tsuji, A.1    Tamai, I.2
  • 9
    • 0343554785 scopus 로고    scopus 로고
    • Role of efflux transport across the blood-brain barrier and blood-cerebrospinal fluid barrier on the disposition of xenobiotics in the central nervous system
    • Suzuki H., Terasaki T., Sugiyama Y. Role of efflux transport across the blood-brain barrier and blood-cerebrospinal fluid barrier on the disposition of xenobiotics in the central nervous system. Adv. Drug Deliv. Rev. 25:1997;257-285.
    • (1997) Adv. Drug Deliv. Rev , vol.25 , pp. 257-285
    • Suzuki, H.1    Terasaki, T.2    Sugiyama, Y.3
  • 10
    • 0033391691 scopus 로고    scopus 로고
    • Blood-brain barrier biology and methodology
    • Pardridge W.M. Blood-brain barrier biology and methodology. J. Neuroviol. 5:1999;556-569.
    • (1999) J. Neuroviol. , vol.5 , pp. 556-569
    • Pardridge, W.M.1
  • 11
    • 0028879235 scopus 로고
    • Effect of inflammatory agents on electrical resistance across the blood-brain barrier in pial microvessels of anaesthetized rats
    • Butt A.M. Effect of inflammatory agents on electrical resistance across the blood-brain barrier in pial microvessels of anaesthetized rats. Brain Res. 696:1995;145-150.
    • (1995) Brain Res , vol.696 , pp. 145-150
    • Butt, A.M.1
  • 13
    • 0023108382 scopus 로고
    • Astrocytes induce blood-brain barrier properties in endothelial cells
    • Janzer R.C., Raff M.C. Astrocytes induce blood-brain barrier properties in endothelial cells. Nature. 325:1987;253-257.
    • (1987) Nature , vol.325 , pp. 253-257
    • Janzer, R.C.1    Raff, M.C.2
  • 14
    • 0024441157 scopus 로고
    • Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture
    • Meresse S., Dehouck M.P., Delorme P., Bensaid M., Tauber J.P., Delbart C., et al. Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture. J. Neurochem. 53:1989;1363-1371.
    • (1989) J. Neurochem , vol.53 , pp. 1363-1371
    • Meresse, S.1    Dehouck, M.P.2    Delorme, P.3    Bensaid, M.4    Tauber, J.P.5    Delbart, C.6
  • 15
    • 0033638592 scopus 로고    scopus 로고
    • Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier
    • Gaillard P.J., van der Sandt I.C.J., Voorwinden L.H., Vu D., Nielsen J.L., de Boer A.G., et al. Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier. Pharm. Res. 17:2000;1198-1205.
    • (2000) Pharm. Res , vol.17 , pp. 1198-1205
    • Gaillard, P.J.1    Van Der Sandt, I.C.J.2    Voorwinden, L.H.3    Vu, D.4    Nielsen, J.L.5    De Boer, A.G.6
  • 16
    • 0037005142 scopus 로고    scopus 로고
    • In Vitro Models of the Blood-Brain Barrier: When to use which? Central nervous system agents
    • De Boer A.G., Gaillard P.J. In Vitro Models of the Blood-Brain Barrier: when to use which? Central nervous system agents. Curr. Med. Chem. 2:2002;203-209.
    • (2002) Curr. Med. Chem , vol.2 , pp. 203-209
    • De Boer, A.G.1    Gaillard, P.J.2
  • 17
    • 0034732233 scopus 로고    scopus 로고
    • Thieno[2,3-b]pyridones as antagonists on the glycine site of the N-methyl-D-aspartate Receptor-binding studies, molecular modeling and structure-activity relationships
    • Buchstaller H.P., Siebert C.D., Lyssy R.H., Ecker G., Krug M., Berger M.L., et al. Thieno[2,3-b]pyridones as antagonists on the glycine site of the N-methyl-D-aspartate Receptor-binding studies, molecular modeling and structure-activity relationships. Sci. Pharm. 68:2000;3-14.
    • (2000) Sci. Pharm. , vol.68 , pp. 3-14
    • Buchstaller, H.P.1    Siebert, C.D.2    Lyssy, R.H.3    Ecker, G.4    Krug, M.5    Berger, M.L.6
  • 18
    • 0031940414 scopus 로고    scopus 로고
    • Inverse agonists at the polyamine-sensitive modulatory site of the NMDA receptor: 50-fold increase in potency by insertion of an aromatic ring into an alkanediamine chain
    • Berger M.L., Schödl C., Noe C.R. Inverse agonists at the polyamine-sensitive modulatory site of the NMDA receptor: 50-fold increase in potency by insertion of an aromatic ring into an alkanediamine chain. Eur. J. Med. Chem. 33:1998;3-14.
    • (1998) Eur. J. Med. Chem , vol.33 , pp. 3-14
    • Berger, M.L.1    Schödl, C.2    Noe, C.R.3
  • 19
    • 0030579090 scopus 로고    scopus 로고
    • Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains
    • Teifl M., Friedl P. Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains. Exp. Cell Res. 228:1996;50-57.
    • (1996) Exp. Cell Res , vol.228 , pp. 50-57
    • Teifl, M.1    Friedl, P.2
  • 20
    • 0014430979 scopus 로고
    • Differential rat glial cell strain in tissue culture
    • Benda P., Lightbody J., Sato G., Levine L., Sweet W. Differential rat glial cell strain in tissue culture. Science. 161:1968;370-371.
    • (1968) Science , vol.161 , pp. 370-371
    • Benda, P.1    Lightbody, J.2    Sato, G.3    Levine, L.4    Sweet, W.5
  • 22
    • 85030914098 scopus 로고    scopus 로고
    • Scifinder Scholar 2002, Cheminal Abstracts Service, American Chemical Society
    • Scifinder Scholar 2002, Cheminal Abstracts Service, American Chemical Society.
  • 23
    • 85030896744 scopus 로고    scopus 로고
    • Molecular Operating Environment (MOE), Chemical Computing Group, Montreal, Canada
    • Molecular Operating Environment (MOE), Chemical Computing Group, Montreal, Canada.
  • 24
    • 0034609833 scopus 로고    scopus 로고
    • Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
    • Ertl P., Rohde B., Selzer P. Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J. Med. Chem. 43:2000;3714-3717.
    • (2000) J. Med. Chem , vol.43 , pp. 3714-3717
    • Ertl, P.1    Rohde, B.2    Selzer, P.3
  • 25
    • 0025899352 scopus 로고
    • Iron absorption by intestinal epithelial cells. 1.) Caco 2 cells cultivated in serum-free medium, on polyethylenterephtalate microporous membranes, as an in vitro model
    • Halleux C., Schneider Y.-J. Iron absorption by intestinal epithelial cells. 1.) Caco 2 cells cultivated in serum-free medium, on polyethylenterephtalate microporous membranes, as an in vitro model. In Vitro Cell. Dev. Biol. 27A:1991;293.
    • (1991) In Vitro Cell. Dev. Biol , vol.27 , pp. 293
    • Halleux, C.1    Schneider, Y.-J.2
  • 27
    • 0024325094 scopus 로고
    • The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
    • Shah M.V., Audus K.L., Borchardt R.T. The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier. Pharm. Res. 6:1989;624-627.
    • (1989) Pharm. Res , vol.6 , pp. 624-627
    • Shah, M.V.1    Audus, K.L.2    Borchardt, R.T.3
  • 29
    • 1042275637 scopus 로고    scopus 로고
    • In silico prediction models for blood-brain barrier permeation
    • [in press]
    • Ecker G.F., Noe C.R. In silico prediction models for blood-brain barrier permeation. Curr. Med. Chem. 2004;. [in press].
    • (2004) Curr. Med. Chem.
    • Ecker, G.F.1    Noe, C.R.2
  • 30
    • 0032714220 scopus 로고    scopus 로고
    • Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs
    • Kelder J., Grootenhuis P.D.J., Bayada D.M., Delbressine L.P.C., Ploemen J.P. Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs. Pharm. Res. 16:1999;1514-1519.
    • (1999) Pharm. Res , vol.16 , pp. 1514-1519
    • Kelder, J.1    Grootenhuis, P.D.J.2    Bayada, D.M.3    Delbressine, L.P.C.4    Ploemen, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.