The Cl-/HCO3- exchanger pendrin in the rat kidney is regulated in response to chronic alterations in chloride balance

American Journal of Physiology - Renal Physiology

Volumn 287, Issue 6 56-6, 2004, Pages

  Quentin, Fabienne ^a   Chambrey, Régine ^a,d   Trinh Trang Tan, Marie Marcelle ^b   Fysekidis, Marinos ^b   Cambillau, Michèle ^b   Paillard, Michel ^a,b   Aronson, Peter S ^c   Eladari, Dominique ^a,b,d  

^a INSERM   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

Acid base; Anion exchanger; Blood pressure; Extracellular volume; HTA

Indexed keywords

AMMONIUM CHLORIDE; CARBONIC ACID; CHLORIDE; FUROSEMIDE; PENDRIN; POTASSIUM CARBONATE; POTASSIUM CHLORIDE; SODIUM CARBONATE; SODIUM CHLORIDE; BICARBONATE; BICARBONATE CHLORIDE ANTIPORTER; PENDRIN PROTEIN, RAT; POTASSIUM BICARBONATE; POTASSIUM DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION EXCHANGE; ARTICLE; BLOOD PRESSURE REGULATION; CHLORIDE BALANCE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; IMMUNOBLOTTING; KIDNEY; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; SALT INTAKE; SODIUM BALANCE; ANIMAL; CELL MEMBRANE; CHEMISTRY; DIET; DRUG EFFECT; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

AMMONIUM CHLORIDE; ANIMALS; BICARBONATES; CELL MEMBRANE; CHLORIDE-BICARBONATE ANTIPORTERS; CHLORIDES; DIET; FUROSEMIDE; HOMEOSTASIS; IMMUNOBLOTTING; KIDNEY; MALE; POTASSIUM CHLORIDE; POTASSIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM BICARBONATE; SODIUM CHLORIDE; SODIUM CHLORIDE, DIETARY;

EID: 8644243107     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00211.2004     Document Type: Article

References (42)

1. +-ATPase. Proc Natl Acad Sci USA 86: 5429-5433, 1989.
2. Bell PD, Lapointe JY, and Peti-Peterdi J. Macula densa cell signaling. Annu Rev Physiol 65: 481-500, 2003.
3. Berthelot M. Violet d'aniline. Rep Chim App 1: 284, 1859.
4. +-ATPase in opposite plasma membrane domains in kidney epithelial cell subpopulations. Nature 331: 622-624, 1988.
5. --transporting epithelia. Proc Natl Acad Sci USA 100: 663-668, 2003.
6. Eladari D, Leviel F, Pezy F, Paillard M, and Chambrey R. Rat proximal NHE3 adapts to chronic acid-base disorders but not to chronic changes in dietary NaCl intake. Am J Physiol Renal Physiol 282: F835-F843, 2002.
7. Everett LA, Glaser B, Beck JC, Idol JR, Buchs A, Heyman M, Adawi F, Hazani E, Nassir E, Baxevanis AD, Sheffield VC, and Green ED. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS). Nat Genet 17: 411-422, 1997.
8. Everett LA and Green ED. A family of mammalian anion transporters and their involvement in human genetic diseases. Hum Mol Genet 8: 1883-1891, 1999.
9. 3 loading. Am J Physiol Renal Physiol 284: F584-F593, 2003.
10. Gillam MP, Sidhaye AR, Lee EJ, Rutishauser J, Waeber Stephan C, and Kopp P. Functional characterization of pendrin in a polarized cell system: evidence for pendrin-mediated apical iodide efflux. J Biol Chem 279: 13004-13010, 2004.
11. Greger R. Chloride transport in thick ascending limb, distal convolution, and collecting duct. Annu Rev Physiol 50: 111-122, 1988.
12. Guyton AC. Blood pressure control: special role of the kidneys and body fluids. Science 252: 1813-1816, 1991.
13. - flux in extrarenal epithelia. Proc Natl Acad Sci USA 101: 2064-2069, 2004.
14. Kim J, Kim YH, Cha JH, Tisher CC, and Madsen KM. Intercalated cell subtypes in connecting tubule and cortical collecting duct of rat and mouse. J Am Soc Nephrol 10: 1-12, 1999.
15. Kim YH, Kwon TH, Frische S, Kim J, Tisher CC, Madsen KM, and Nielsen S. Immunocytochemical localization of pendrin in intercalated cell subtypes in rat and mouse kidney. Am J Physiol Renal Physiol 283: F744-F754, 2002.
16. Knauf F, Yang CL, Thomson RB, Mentone SA, Giebisch G, and Aronson PS. Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci USA 98: 9425-9430, 2001.
17. Lapointe JY, Laamarti A, Hurst AM, Fowler BC, and Bell PD. Activation of Na:2Cl:K cotransport by luminal chloride in macula densa cells. Kidney Int 47: 752-757, 1995.
18. Li XC, Everett LA, Lalwani AK, Desmukh D, Friedman TB, Green ED, and Wilcox ER. A mutation in PDS causes non-syndromic recessive deafness. Nat Genet 18: 215-217, 1998.
19. Lorenz JN, Weihprecht H, Schnermann J, Skøtt O, and Briggs JP. Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport. Am J Physiol Renal Fluid Electrolyte Physiol 260: F486-F493, 1991.
20. Masilamani S, Wang X, Kim GH, Brooks H, Nielsen J, Nielsen S, Nakamura K, Stokes JB, and Knepper MA. Time course of renal Na-K-ATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction. Am J Physiol Renal Physiol 283: F648-F657, 2002.
21. Pendred V. Deaf mutism and goitre. Lancet II: 532, 1896.
22. 2 release from macula densa cells. J Clin Invest 112: 76-82, 2003.
23. - exchanger pendrin in rat cortical collecting duct in metabolic acidosis. Am J Physiol Renal Physiol 284: F103-F112, 2003.
24. Reeves WB and Molony DA. The physiology of loop diuretic action. Semin Nephrol 8: 225-233, 1988.
25. Royaux IE, Suzuki K, Mori A, Katoh R, Everett LA, Kohn LD, Green ED, Li XC, Lahvani AK, Desmukh D, Friedman TB, Wilcox ER, Glaser B, Beck JC, Idol JR, Buchs A, Heyman M, Adawi F, Hazani E, Nassir E, Baxevanis AD, and Sheffield VC. Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology 141: 839-845, 2000.
26. Royaux IE, Wall SM, Karniski LP, Everett LA, Suzuki K, Knepper MA, and Green ED. Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc Natl Acad Sci USA 98: 4221-4226, 2001.
27. Salomonsson M, Gonzalez E, Westerlund P, and Persson AE. Chloride concentration in macula densa and cortical thick ascending limb cells. Kidney Int Suppl 32: S51-54, 1991.
28. Schambelan M, Sebastian A, and Rector FC Jr. Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption. Kidney Int 19: 716-727, 1981.
29. Schmitt R, Ellison DH, Farman N, Rossier BC, Reilly RF, Reeves WB, Oberbaumer I, Tapp R, and Bachmann S. Developmental expression of sodium entry pathways in rat nephron. Am J Physiol Renal Physiol 276: F367-F381, 1999.
30. Schmitt R, Klussmann E, Kahl T, Ellison DH, and Bachmann S. Renal expression of sodium transporters and aquaporin-2 in hypothyroid rats. Am J Physiol Renal Physiol 284: F1097-F1104, 2003.
31. Schuster VL. Function and regulation of collecting duct intercalated cells. Annu Rev Physiol 55: 267-288, 1993.
32. Schuster VL and Stokes JB. Chloride transport by the cortical and outer medullary collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 253: F203-F212, 1987.
33. Scott DA and Karniski LP. Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange. Am J Physiol Cell Physiol 278: C207-C211, 2000.
34. Scott DA, Wang R, Kreman TM, Sheffield VC, and Karniski LP. The Pendred syndrome gene encodes a chloride-iodide transport protein. Nat Genet 21: 440-443, 1999.
35. - exchanger in the kidney cortex. Am J Physiol Renal Physiol 280: F356-F364, 2001.
36. Verlander JW, Hassell KA, Royaux IE, Glapion DM, Wang ME, Everett LA, Green ED, and Wall SM. Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension. Hypertension 42: 356-362, 2003.
37. Verlander JW, Madsen KM, and Tisher CC. Effect of acute respiratory acidosis on two populations of intercalated cells in rat cortical collecting duct. Am J Physiol Renal Fluid Electrolyte Physiol 253: F1142-F1156, 1987.
38. -/anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int 62: 2109-2117, 2002.
39. Wall SM, Hassell KA, Royaux IE, Green ED, Chang JY, Shipley GL, and Verlander JW. Localization of pendrin in mouse kidney. Am J Physiol Renal Physiol 284: F229-F241, 2003.
40. Wilson FH, Disse-Nicodeme S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, and Lifton RP. Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112, 2001.
41. Wilson FH, Kahle KT, Sabath E, Lalioti MD, Rapson AK, Hoover RS, Hebert SC, Gamba G, and Lifton RP. Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc Natl Acad Sci USA 100: 680-684, 2003.
42. Yang CL, Angell J, Mitchell R, and Ellison DH. WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J Clin Invest 111: 1039-1045, 2003.