Pendrin in the mouse kidney is primarily regulated by Cl- excretion but also by systemic metabolic acidosis

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 6, 2008, Pages

  Hafner, Patricia ^a   Grimaldi, Rosa ^a,b   Capuano, Paola ^a   Capasso, Giovambattista ^b   Wagner, Carsten A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Collecting duct; Transporter

Indexed keywords

ACETAZOLAMIDE; AMMONIUM CHLORIDE; CHLORINE; PENDRIN;

ACID BASE BALANCE; ANIMAL TISSUE; ARTICLE; CHLORIDE URINE LEVEL; CONTROLLED STUDY; KIDNEY; KIDNEY COLLECTING TUBULE; METABOLIC ACIDOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; URINARY EXCRETION; URINE ACIDIFICATION;

ACETAZOLAMIDE; ACID-BASE EQUILIBRIUM; ACIDOSIS; AMMONIUM CHLORIDE; ANIMALS; ANION TRANSPORT PROTEINS; BLOTTING, WESTERN; CHLORIDES; DIURETICS; IMMUNOHISTOCHEMISTRY; KIDNEY; MICE;

ANIMALIA; MUS;

EID: 57349093878     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00419.2008     Document Type: Article

References (30)

1. Adler L, Efrati E, Zelikovic I. Molecular mechanisms of epithelial cell-specific expression and regulation of the human anion exchanger (pendrin) gene. Am J Physiol Cell Physiol 294: C1261-C1276, 2008.
2. Amlal H, Sheriff S, Faroqui S, Ma L, Barone S, Petrovic S, Soleimani M. Regulation of acid-base transporters by vasopressin in the kidney collecting duct of Brattleboro rat. Am J Nephrol 26: 194-205, 2006.
3. Bagnis C, Marshansky V, Breton S, Brown D. Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition. Am J Physiol Renal Physiol 280: F437-F448, 2001.
4. Brown D, Lydon J, McLaughlin M, Stuart-Tilley A, Tyszkowski R, Alper S. Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem Cell Biol 105: 261-267, 1996.
5. Chan JC. The rapid determination of urinary titratable acid and ammonium and evaluation of freezing as a method of preservation. Clin Biochem 5: 94-98, 1972.
6. Eckardt KU, Kurtz A, Bauer C. Regulation of erythropoietin production is related to proximal tubular function. Am J Physiol Renal Fluid Electrolyte Physiol 256: F942-F947, 1989.
7. Everett LA, Glaser B, Beck JC, Idol JR, Buchs A, Heyman M, Adawi F, Hazani E, Nassir E, Baxevanis AD, Sheffield VC, Green ED. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS). Nat Genet 17: 411-422, 1997.
8. Everett LA, Green ED. A family of mammalian anion transporters and their involvement in human genetic diseases. Hum Mol Genet 8: 1883-1891, 1999.
9. 3 loading. Am J Physiol Renal Physiol 284: F584-F593, 2003.
10. Greger R. Chloride transport in thick ascending limb, distal convolution, and collecting duct. Annu Rev Physiol 50: 111-122, 1988.
11. Jentsch TJ. Chloride transport in the kidney: lessons from human disease and knockout mice. J Am Soc Nephrol 16: 1549-1561, 2005.
12. Khanna A, Simoni J, Wesson DE. Endothelin-induced increased aldosterone activity mediates augmented distal nephron acidification as a result of dietary protein. J Am Soc Nephrol 16: 1929-1935, 2005.
13. Kim YH, Kwon TH, Frische S, Kim J, Tisher CC, Madsen KM, Nielsen S. Immunocytochemical localization of pendrin in intercalated cell subtypes in rat and mouse kidney. Am J Physiol Renal Physiol 283: F744-F754, 2002.
14. Knauf F, Yang CL, Thomson RB, Mentone SA, Giebisch G, Aronson PS. Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells. Proc Natl Acad Sci USA 98: 9425-9430, 2001.
15. McLean IW, Nakane PK. Periodate-lysine-paraformaldehyde fixative. J Histochem Cytochem 22: 1077-1083, 1974.
16. Mount DB, Romero MF. The SLC26 gene family of multifunctional anion exchangers. Pflügers Arch 447: 710-721, 2004.
17. Pech V, Kim YH, Weinstein AM, Everett LA, Pham TD, Wall SM. Angiotensin II increases chloride absorption in the cortical collecting duct in mice through a pendrin-dependent mechanism. Am J Physiol Renal Physiol 292: F914-F920, 2007.
18. - exchanger pendrin in rat cortical collecting duct in metabolic acidosis. Am J Physiol Renal Physiol 284: F103-F112, 2003.
19. - exchanger pendrin in the rat kidney is regulated in response to chronic alterations in chloride balance. Am J Physiol Renal Physiol 287: F1179-F1188, 2004.
20. Royaux IE, Wall SM, Karniski LP, Everett LA, Suzuki K, Knepper MA, Green ED. Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion. Proc Natl Acad Sci USA 98: 4221-4226, 2001.
21. - exchanger in the kidney cortex. Am J Physiol Renal Physiol 280: F356-F364, 2001.
22. +-ATPase subunit defective in an inherited form of distal renal tubular acidosis. J Am Soc Nephrol 14: 3027-3038, 2003.
23. Teng-umnuay P, Verlander JW, Yuan W, Tisher CC, Madsen KM. Identification of distinct subpopulations of intercalated cells in the mouse collecting duct. J Am Soc Nephrol 7: 260-274, 1996.
24. Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Deschenes G, Breton S, Meneton P, Loffing J, Aronson PS, Chambrey R, Eladari D. Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol 17: 2153-2163, 2006.
25. Verlander JW, Hassell KA, Royaux IE, Glapion DM, Wang ME, Everett LA, Green ED, Wall SM. Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension. Hypertension 42: 356-362, 2003.
26. - restriction upregulates pendrin expression within the apical plasma membrane of type B intercalated cells. Am J Physiol Renal Physiol 291: F833-F839, 2006.
27. -/anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int 62: 2109-2117, 2002.
28. Wall SM, Hassell KA, Royaux IE, Green ED, Chang JY, Shipley GL, Verlander JW. Localization of pendrin in mouse kidney. Am J Physiol Renal Physiol 284: F229-F241, 2003.
29. - conservation. Hypertension 44: 982-987, 2004.
30. Wesson DE. Dietary acid increases blood and renal cortical acid content in rats. Am J Physiol Renal Physiol 274: F97-F103, 1998.