메뉴 건너뛰기




Volumn 96, Issue 2, 2012, Pages 200-213

AKT3, ANGPTL4, eNOS3, and VEGFA associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan plateau

Author keywords

Acute and chronic mountain sickness; AKT3; ANGPTL4; eNOS3; Response element; Transcriptional factors; VEGFA

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GENOMIC DNA; HEMOGLOBIN; PROTEIN KINASE B; VASCULOTROPIN A;

EID: 84867021164     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-012-1117-7     Document Type: Article
Times cited : (35)

References (60)
  • 4
    • 0342798924 scopus 로고
    • Chronic mountain sickness
    • Monge C. Chronic mountain sickness. Physiol Rev. 1943;23: 166-84.
    • (1943) Physiol Rev , vol.23 , pp. 166-184
    • Monge, C.1
  • 6
    • 0034913630 scopus 로고    scopus 로고
    • Human genetic adaptation to high altitude
    • Moore LG. Human genetic adaptation to high altitude. High Alt Med Biol. 2001;2:257-79.
    • (2001) High Alt Med Biol , vol.2 , pp. 257-279
    • Moore, L.G.1
  • 8
    • 0842334690 scopus 로고    scopus 로고
    • Proposal for scoring severity in chronic mountain sickness (cms) background and conclusions of the cms working group
    • Leon-Velarde F, McCullough RG, McCullough RE, Reeves JT. Proposal for scoring severity in chronic mountain sickness (CMS). Background and conclusions of the CMS Working Group. Adv Exp Med Biol. 2003;543:339-54.
    • (2003) Adv Exp Med Biol , vol.543 , pp. 339-354
    • Leon-Velarde, F.1    McCullough, R.G.2    McCullough, R.E.3    Reeves, J.T.4
  • 9
    • 75149180988 scopus 로고    scopus 로고
    • Regulation of cerebral blood flow in mammals during chronic hypoxia: A matter of balance
    • Ainslie PN, Ogoh S. Regulation of cerebral blood flow in mammals during chronic hypoxia: a matter of balance. Exp Physiol. 2010;95:251-62.
    • (2010) Exp Physiol , vol.95 , pp. 251-262
    • Ainslie, P.N.1    Ogoh, S.2
  • 10
    • 70449431905 scopus 로고    scopus 로고
    • Erythropoietin modulates the neural control of hypoxic ventilation. Cellular and molecular life sciences
    • Gassmann M, Soliz J. Erythropoietin modulates the neural control of hypoxic ventilation. Cellular and molecular life sciences. CMLS. 2009;66:3575-82.
    • (2009) CMLS , vol.66 , pp. 3575-3582
    • Gassmann, M.1    Soliz, J.2
  • 11
    • 8744311537 scopus 로고    scopus 로고
    • The physiologic basis of high-altitude diseases
    • West JB. The physiologic basis of high-altitude diseases. Ann Intern Med. 2004;141:789-800.
    • (2004) Ann Intern Med , vol.141 , pp. 789-800
    • West, J.B.1
  • 12
    • 41749117048 scopus 로고    scopus 로고
    • Lessons in hypoxic adaptation from high-altitude populations
    • Strohl KP. Lessons in hypoxic adaptation from high-altitude populations. Sleep Breath. 2008;12:115-21.
    • (2008) Sleep Breath , vol.12 , pp. 115-121
    • Strohl, K.P.1
  • 13
    • 58249139466 scopus 로고    scopus 로고
    • The cerebral effects of ascent to high altitudes
    • Wilson MH, Newman S, Imray CH. The cerebral effects of ascent to high altitudes. Lancet Neurol. 2009;8:175-91.
    • (2009) Lancet Neurol , vol.8 , pp. 175-191
    • Wilson, M.H.1    Newman, S.2    Imray, C.H.3
  • 15
    • 0028040151 scopus 로고
    • Mitochondrial DNA analysis in Tibet: Implications for the origin of the Tibetan population and its adaptation to high altitude
    • Torroni A, Miller JA, Moore LG, Zamudio S, Zhuang J, Droma T, Wallace DC. Mitochondrial DNA analysis in Tibet: implications for the origin of the Tibetan population and its adaptation to high altitude. Am J Phys Anthropol. 1994;93:189-99.
    • (1994) Am J Phys Anthropol , vol.93 , pp. 189-199
    • Torroni, A.1    Miller, J.A.2    Moore, L.G.3    Zamudio, S.4    Zhuang, J.5    Droma, T.6    Wallace, D.C.7
  • 16
    • 0006714350 scopus 로고    scopus 로고
    • Genetic distances between Chinese populations calculated on gene frequencies of 38 loci
    • Du R, Xiao C, Cavalli-Sforza LL. Genetic distances between Chinese populations calculated on gene frequencies of 38 loci. Sci China C Life Sci. 1997;40:613-21.
    • (1997) Sci China C Life Sci , vol.40 , pp. 613-621
    • Du, R.1    Xiao, C.2    Cavalli-Sforza, L.L.3
  • 17
    • 0033914877 scopus 로고    scopus 로고
    • Plasma vascular endothelial growth factor in acute mountain sickness
    • Maloney J, Wang D, Duncan T, Voelkel N, Ruoss S. Plasma vascular endothelial growth factor in acute mountain sickness. Chest. 2000;118:47-52.
    • (2000) Chest , vol.118 , pp. 47-52
    • Maloney, J.1    Wang, D.2    Duncan, T.3    Voelkel, N.4    Ruoss, S.5
  • 18
    • 33846846673 scopus 로고    scopus 로고
    • Change in plasma vascular endothelial growth factor during onset and recovery from acute mountain sickness
    • Dorward DA, Thompson AA, Baillie JK, MacDougall M, Hirani N. Change in plasma vascular endothelial growth factor during onset and recovery from acute mountain sickness. Respir Med. 2007;101:587-94.
    • (2007) Respir Med , vol.101 , pp. 587-594
    • Dorward, D.A.1    Thompson, A.A.2    Baillie, J.K.3    MacDougall, M.4    Hirani, N.5
  • 20
    • 46249111510 scopus 로고    scopus 로고
    • High altitude adaptation: Genetic perspectives
    • Stobdan T, Karar J, Pasha MA. High altitude adaptation: genetic perspectives. High Alt Med Biol. 2008;9:140-7.
    • (2008) High Alt Med Biol , vol.9 , pp. 140-147
    • Stobdan, T.1    Karar, J.2    Pasha, M.A.3
  • 23
    • 33745902783 scopus 로고    scopus 로고
    • Evidence for a genetic basis for altituderelated illness
    • Rupert JL, Koehle MS. Evidence for a genetic basis for altituderelated illness. High Alt Med Biol. 2006;7:150-67.
    • (2006) High Alt Med Biol , vol.7 , pp. 150-167
    • Rupert, J.L.1    Koehle, M.S.2
  • 26
    • 0037072457 scopus 로고    scopus 로고
    • Positive association of the endothelial nitric oxide synthase gene polymorphisms with highaltitude pulmonary edema
    • Droma Y, Hanaoka M, Ota M, Katsuyama Y, Koizumi T, Fujimoto K, Kobayashi T, Kubo K. Positive association of the endothelial nitric oxide synthase gene polymorphisms with highaltitude pulmonary edema. Circulation. 2002;106:826-30.
    • (2002) Circulation , vol.106 , pp. 826-830
    • Droma, Y.1    Hanaoka, M.2    Ota, M.3    Katsuyama, Y.4    Koizumi, T.5    Fujimoto, K.6    Kobayashi, T.7    Kubo, K.8
  • 27
    • 58149125437 scopus 로고    scopus 로고
    • Polymorphisms of human vascular endothelial growth factor gene in high-altitude pulmonary oedema susceptible subjects
    • Hanaoka M, Droma Y, Ota M, Ito M, Katsuyama Y, Kubo K. Polymorphisms of human vascular endothelial growth factor gene in high-altitude pulmonary oedema susceptible subjects. Respirology. 2009;14:46-52.
    • (2009) Respirology , vol.14 , pp. 46-52
    • Hanaoka, M.1    Droma, Y.2    Ota, M.3    Ito, M.4    Katsuyama, Y.5    Kubo, K.6
  • 28
    • 77955054511 scopus 로고
    • The diagnoses accord with the Lake Louise scoring system
    • Sutton GC JR, Houston CS, editors. New York: Pergamon Press
    • Hackett PH, Oelz O (1992). The diagnoses accord with the Lake Louise scoring system. In: Sutton GC JR, Houston CS, editors. Hypoxia and mountain sickness. New York: Pergamon Press, pp. 327-330.
    • (1992) Hypoxia and Mountain Sickness , pp. 327-330
    • Hackett, P.H.1    Oelz, O.2
  • 30
    • 0015990369 scopus 로고
    • Sampling variances of heterozygosity and genetic distance
    • Nei M, Roychoudhury AK. Sampling variances of heterozygosity and genetic distance. Genetics. 1974;76:379-90.
    • (1974) Genetics , vol.76 , pp. 379-390
    • Nei, M.1    Roychoudhury, A.K.2
  • 31
    • 67349176068 scopus 로고    scopus 로고
    • Genetics in geographically structured populations: Defining, estimating and interpreting F(ST)
    • Holsinger KE, Weir BS. Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nat Rev Genet. 2009;10:639-50.
    • (2009) Nat Rev Genet , vol.10 , pp. 639-650
    • Holsinger, K.E.1    Weir, B.S.2
  • 32
    • 0242475326 scopus 로고    scopus 로고
    • LDA-A java-based linkage disequilibrium analyzer
    • Ding K, Zhou K, He F, Shen Y. LDA-a java-based linkage disequilibrium analyzer. Bioinformatics. 2003;19:2147-8.
    • (2003) Bioinformatics , vol.19 , pp. 2147-2148
    • Ding, K.1    Zhou, K.2    He, F.3    Shen, Y.4
  • 36
    • 3242891274 scopus 로고    scopus 로고
    • ConSite: Web-based prediction of regulatory elements using cross-species comparison
    • Sandelin A, Wasserman WW, Lenhard B. ConSite: web-based prediction of regulatory elements using cross-species comparison. Nucleic Acids Res. 2004;32:W249-52.
    • (2004) Nucleic Acids Res , vol.32
    • Sandelin, A.1    Wasserman, W.W.2    Lenhard, B.3
  • 38
    • 77955255788 scopus 로고    scopus 로고
    • Molecular diversity of VEGF-A as a regulator of its biological activity
    • Woolard J, Bevan HS, Harper SJ, Bates DO. Molecular diversity of VEGF-A as a regulator of its biological activity. Microcirculation. 2009;16:572-92.
    • (2009) Microcirculation , vol.16 , pp. 572-592
    • Woolard, J.1    Bevan, H.S.2    Harper, S.J.3    Bates, D.O.4
  • 41
    • 65449115676 scopus 로고    scopus 로고
    • Angiogenic/lymphangiogenic factors and adaptation to extreme altitudes during an expedition to Mount Everest
    • Patitucci M, Lugrin D, Pages G. Angiogenic/lymphangiogenic factors and adaptation to extreme altitudes during an expedition to Mount Everest. Acta Physiol. 2009;196:259-65.
    • (2009) Acta Physiol , vol.196 , pp. 259-265
    • Patitucci, M.1    Lugrin, D.2    Pages, G.3
  • 42
    • 21844453669 scopus 로고    scopus 로고
    • Hypoxia-induced expression of HIF-1alpha and its target genes in umbilical venous endothelial cells of Tibetans and immigrant Han
    • Gao W, Gao Y, Zhang G, Song L, Sun B, Shi J. Hypoxia-induced expression of HIF-1alpha and its target genes in umbilical venous endothelial cells of Tibetans and immigrant Han. Comp Biochem Physiol Toxicol Pharmacol. 2005;141:93-100.
    • (2005) Comp Biochem Physiol Toxicol Pharmacol , vol.141 , pp. 93-100
    • Gao, W.1    Gao, Y.2    Zhang, G.3    Song, L.4    Sun, B.5    Shi, J.6
  • 44
    • 35348855682 scopus 로고    scopus 로고
    • VEGF: An essential mediator of both angiogenesis and endochondral ossification
    • Dai J, Rabie AB. VEGF: an essential mediator of both angiogenesis and endochondral ossification. J Dent Res. 2007;86: 937-50.
    • (2007) J Dent Res , vol.86 , pp. 937-950
    • Dai, J.1    Rabie, A.B.2
  • 45
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: The key to anti-angiogenic therapeutics?
    • Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer. 2008;8:880-7.
    • (2008) Nat Rev Cancer , vol.8 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 46
    • 80052899736 scopus 로고    scopus 로고
    • The evolution of alternative splicing exons in vascular endothelial growth factor A
    • Xu J, Dou T, Liu C, Fu M, Huang Y, Gu S, Zhou Y, Xie Y. The evolution of alternative splicing exons in vascular endothelial growth factor A. Gene. 2011;487:143-50.
    • (2011) Gene , vol.487 , pp. 143-150
    • Xu, J.1    Dou, T.2    Liu, C.3    Fu, M.4    Huang, Y.5    Gu, S.6    Zhou, Y.7    Xie, Y.8
  • 47
    • 14844357211 scopus 로고    scopus 로고
    • The vascular endothelial growth factor (VEGF) family: Angiogenic factors in health and disease
    • Holmes DI, Zachary I. The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease. Genome Biol. 2005;6:209.
    • (2005) Genome Biol , vol.6 , pp. 209
    • Holmes, D.I.1    Zachary, I.2
  • 48
    • 79952281081 scopus 로고    scopus 로고
    • Polymorphisms of hypoxia-related genes in subjects susceptible to acute mountain sickness
    • Ding H, Liu Q, Hua M, Ding M, Du H, Zhang W, Li Z, Zhang J. Polymorphisms of hypoxia-related genes in subjects susceptible to acute mountain sickness. Respiration. 2011;81:236-41.
    • (2011) Respiration , vol.81 , pp. 236-241
    • Ding, H.1    Liu, Q.2    Hua, M.3    Ding, M.4    Du, H.5    Zhang, W.6    Li, Z.7    Zhang, J.8
  • 49
    • 28844448182 scopus 로고    scopus 로고
    • Oncogenic PI3K deregulates transcription and translation
    • Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer. 2005;5: 921-9.
    • (2005) Nat Rev Cancer , vol.5 , pp. 921-929
    • Bader, A.G.1    Kang, S.2    Zhao, L.3    Vogt, P.K.4
  • 50
    • 84858079914 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR pathway in angiogenesis
    • Karar J, Maity A. PI3K/AKT/mTOR pathway in angiogenesis. Front Mol Neurosci. 2011;4:51.
    • (2011) Front Mol Neurosci , vol.4 , pp. 51
    • Karar, J.1    Maity, A.2
  • 51
    • 0035949699 scopus 로고    scopus 로고
    • AKT plays a central role in tumorigenesis
    • Testa JR, Bellacosa A. AKT plays a central role in tumorigenesis. Proc Natl Acad Sci USA. 2001;98:10983-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10983-10985
    • Testa, J.R.1    Bellacosa, A.2
  • 52
    • 70349484821 scopus 로고    scopus 로고
    • Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness
    • Wang P, Koehle MS, Rupert JL. Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with susceptibility to acute mountain sickness. High Alt Med Biol. 2009;10:261-7.
    • (2009) High Alt Med Biol , vol.10 , pp. 261-267
    • Wang, P.1    Koehle, M.S.2    Rupert, J.L.3
  • 53
    • 47949114441 scopus 로고    scopus 로고
    • Relation of the Glu298Asp polymorphism of the nitric oxide synthase gene to hypertension and serum cholesterol in Japanese workers
    • Sawada T, Kishimoto T, Osaki Y, Okamoto M, Tahara A, Kaetu A, Kurosawa Y, Kotani K. Relation of the Glu298Asp polymorphism of the nitric oxide synthase gene to hypertension and serum cholesterol in Japanese workers. Prev Med. 2008;47: 167-71.
    • (2008) Prev Med , vol.47 , pp. 167-171
    • Sawada, T.1    Kishimoto, T.2    Osaki, Y.3    Okamoto, M.4    Tahara, A.5    Kaetu, A.6    Kurosawa, Y.7    Kotani, K.8
  • 54
    • 35748964459 scopus 로고    scopus 로고
    • Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians
    • Srivastava K, Narang R, Sreenivas V, Das S, Das N. Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians. Clin Chim Acta. 2008;387:80-3.
    • (2008) Clin Chim Acta , vol.387 , pp. 80-83
    • Srivastava, K.1    Narang, R.2    Sreenivas, V.3    Das, S.4    Das, N.5
  • 59
    • 24644466927 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in transcriptional regulatory regions and expression of environmentally responsive genes
    • Wang X, Tomso DJ, Liu X, Bell DA. Single nucleotide polymorphism in transcriptional regulatory regions and expression of environmentally responsive genes. Toxicol Appl Pharmacol. 2005;207:84-90.
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 84-90
    • Wang, X.1    Tomso, D.J.2    Liu, X.3    Bell, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.