Podocytes: A new player for glutamate signaling

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 12, 2012, Pages 2272-2277

  Armelloni, S ^a   Li, M ^a   Messa, P ^a   Rastaldi, M P ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

Foot processes; Nephrin; Neurotransmitter receptors; Podocyte; Vesicles

Indexed keywords

ACTIN BINDING PROTEIN; ADDUCIN; ALPHA ACTININ 4; CADHERIN; CELL ADHESION MOLECULE; CYCLOSPORIN A; DENDRIN; DENSIN; DREBRIN; EPHRIN B1; GLUTAMATE RECEPTOR; GLUTAMIC ACID; IMMUNOSUPPRESSIVE AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEPHRIN; NEUREXIN; PODOCALYXIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN; PROTEIN CASK; PROTEIN GLEPP1; PROTEIN GRM1; PROTEIN KINASE FYN; PROTEIN MAGI; PROTOCADHERIN; RITUXIMAB; SIDEKICK PROTEIN; STEROID; SYNAPTOPODIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CAPILLARY BASEMENT MEMBRANE; CELL COMMUNICATION; CELL DAMAGE; CELL FUNCTION; CELL JUNCTION; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; ENDOCYTOSIS; EXOCYTOSIS; FOCAL GLOMERULOSCLEROSIS; GLOMERULUS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FAILURE; MICTURITION; NERVE CELL; NONHUMAN; PATHOGENESIS; PODOCYTE; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84867013866     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.09.014     Document Type: Short Survey

References (58)

1. P. Aaltonen, and H. Holthöfer The nephrin-based slit diaphragm: new insight into the signaling platform identifies targets for therapy Nephrology, Dialysis, Transplantation 22 2007 3408 3410
2. H. Ahola, E. Heikkilä, E. Aström, M. Inagaki, I. Izawa, and H. Pavenstädt A novel protein, densin, expressed by glomerular podocytes Journal of the American Society of Nephrology 14 July (7) 2003 1731 1737
3. R. Balazs Trophic effect of glutamate Current Topics in Medicinal Chemistry 6 10 2006 961 968
4. O. Beltcheva, S. Kontusaari, S. Fetissov, H. Putaala, P. Kilpeläinen, and T. Hökfelt Alternatively used promoters and distinct elements direct tissue-specific expression of nephrin Journal of the American Society of Nephrology 14 February (2) 2003 352 358
5. D.L. Benson, D.R. Colman, and G.W. Huntley Molecules, maps and synapse specificity Nature Reviews Neuroscience 2 2001 899 909
6. C.F. Bigge Ionotropic glutamate receptors Current Opinion in Chemical Biology 3 August (4) 1999 441 447
7. N. Braun, F. Schmutzler, C. Lange, A. Perna, G. Remuzzi, and T. Risler Immunosuppressive treatment for focal segmental glomerulosclerosis in adults Cochrane Database of Systematic Reviews 3 2008 CD003233
8. E.W. Brunskill, K. Georgas, B. Rumballe, M.H. Little, and S.S. Potter Defining the molecular character of the developing and adult kidney podocyte PLoS ONE 6 2011 e24640
9. L.A. Cingolani, and Y. Goda Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy Nature Reviews Neuroscience 9 2008 344 356
10. V. D'Agati Pathologic classification of focal segmental glomerulosclerosis Seminars in Nephrology 23 2003 117 134
11. R. Doyonnas, D.B. Kershaw, C. Duhme, H. Merkens, S. Chelliah, and T. Graf Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin Journal of Experimental Medicine 194 July (1) 2001 13 27
12. C. Faul, K. Asanuma, E. Yanagida-Asanuma, K. Kim, and P. Mundel Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton Trends in Cell Biology 17 2007 428 437
13. C. Faul, M. Donnelly, S. Merscher-Gomez, Y.H. Chang, S. Franz, and J. Delfgaauw The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A Nature Medicine 14 2008 931 938
14. A. Fornoni, J. Sageshima, C. Wei, S. Merscher-Gomez, R. Aguillon-Prada, and A.N. Jauregui Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis Science Translational Medicine 3 2011 85ra46
15. P.G. Genever, and T.M. Skerry Regulation of spontaneous glutamate release activity in osteoblastic cells and its role in differentiation and survival: evidence for intrinsic glutamatergic signaling in bone FASEB Journal 15 2001 1586 1588
16. L. Giardino, S. Armelloni, A. Corbelli, D. Mattinzoli, C. Zennaro, and D. Guerrot Podocyte glutamatergic signaling contributes to the function of the glomerular filtration barrier Journal of the American Society of Nephrology 20 2009 1929 1940
17. A. Greka, and P. Mundel Cell biology and pathology of podocytes Annual Review of Physiology 74 2012 299 323
18. L. Gu, X. Liang, L. Wang, Y. Yan, Z. Ni, and H. Dai Functional metabotropic glutamate receptors 1 and 5 are expressed in murine podocytes Kidney International 81 March (5) 2012 458 468
19. M. Hayashi, H. Yamada, S. Uehara, R. Morimoto, A. Muroyama, and S. Yatsushiro Secretory granule-mediated co-secretion of l-glutamate and glucagon triggers glutamatergic signal transmission in islets of Langerhans Journal of Biological Chemistry 278 January (3) 2003 1966 1974
20. B. Hartleben, H. Schweizer, P. Lübben, M.P. Bartram, C.C. Möller, and R. Herr Neph-nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity Journal of Biological Chemistry 283 August (34) 2008 23033 23038
21. T. Hashimoto, T. Karasawa, A. Saito, N. Miyauchi, G.D. Han, and K. Hayasaka Ephrin-B1 localizes at the slit diaphragm of the glomerular podocyte Kidney International 72 2007 954 964
22. I.S. Hitchcock, T.M. Skerry, M.R. Howard, and P.G. Genever NMDA receptor mediated regulation of human megakaryocytopoiesis Blood 102 2003 1254 1259
23. J. Juhila, M. Lassila, R. Roozendaal, E. Lehtonen, M. Messing, and B. Langer Inducible nephrin transgene expression in podocytes rescues nephrin-deficient mice from perinatal death American Journal of Pathology 176 January (1) 2010 51 63
24. M. Julio-Pieper, P.J. Flor, T.G. Dinan, and J.F. Cryan Exciting times beyond the brain: metabotropic glutamate receptors in peripheral and non-neural tissues Pharmacological Reviews 63 2011 35 58
25. N. Kobayashi Mechanism of the process formation; podocytes vs. neurons Microscopy Research and Technique 57 May (4) 2002 217 223
26. N. Kobayashi, S.Y. Gao, J. Chen, K. Saito, K. Miyawaki, and C.Y. Li Process formation of the renal glomerular podocyte: is there common molecular machinery for processes of podocytes and neurons? Anatomical Science International 79 2004 1 10
27. W. Kriz Ontogenetic development of the filtration barrier Nephron Experimental Nephrology 106 2 2007 e44 e50
28. A. Lau, and M. Tymianski Glutamate receptors, neurotoxicity and neurodegeneration Pflugers Archiv 460 July (2) 2010 525 542
29. M. Li, S. Armelloni, M. Ikehata, A. Corbelli, M. Pesaresi, and N. Calvaresi Nephrin expression in adult rodent central nervous system and its interaction with glutamate receptors Journal of Pathology 225 September (1) 2011 118 128
30. M.T. Lindenmeyer, F. Eichinger, K. Sen, H.J. Anders, I. Edenhofer, and D. Mattinzoli Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset PLoS ONE 5 July (7) 2010 e11545
31. D.E. Matthews, M.A. Marano, and R.G. Campbell Splanchnic bed utilization of glutamine and glutamic acid in humans American Journal of Physiology 264 June (6 Pt 1) 1993 E848 E854
32. M.J. Moeller, I.A. Kovari, and L.B. Holzman Evaluation of a new tool for exploring podocyte biology: mouse Nphs1 5′ flanking region drives LacZ expression in podocytes Journal of the American Society of Nephrology 11 December (12) 2000 2306 2314
33. Y. Moriyama, and M. Hayashi Glutamate-mediated signaling in the islets of Langerhans: a thread entangled Trends in Pharmacological Sciences 24 2003 511 517
34. P. Mundel, H.W. Heid, T.M. Mundel, M. Krüger, J. Reiser, and W. Kriz Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes Journal of Cell Biology 139 October (1) 1997 193 204
35. C.M. Niswender, and P.J. Conn Metabotropic glutamate receptors: physiology, pharmacology, and disease Annual Review of Pharmacology and Toxicology 50 2010 295 322
36. E. Neumann-Haefelin, A. Kramer-Zucker, K. Slanchev, B. Hartleben, F. Noutsou, and K. Martin A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis Human Molecular Genetics 19 June (12) 2010 2347 2359
37. J. Patrakka, and K. Tryggvason New insights into the role of podocytes in proteinuria Nature Reviews Nephrology 5 2009 463 468
38. H. Pavenstädt, W. Kriz, and M. Kretzler Cell biology of the glomerular podocyte Physiological Reviews 83 2003 253 307
39. W.K. Peitsch, I. Hofmann, N. Endlich, S. Prätzel, C. Kuhn, and H. Spring Cell biological and biochemical characterization of drebrin complexes in mesangial cells and podocytes of renal glomeruli Journal of the American Society of Nephrology 14 June (6) 2003 1452 1463
40. M. Pezzella, N.S. Yeghiazaryan, P. Veggiotti, A. Bettinelli, G. Giudizioso, and F. Zara Galloway-Mowat syndrome: an early-onset progressive encephalopathy with intractable epilepsy associated to renal impairment. Two novel cases and review of literature Seizure 19 2010 132 135
41. M. Piper, K. Georgas, T. Yamada, and M. Little Expression of the vertebrate Slit gene family and their putative receptors, the Robo genes, in the developing murine kidney Mechanisms of Development 94 2000 213 217
42. A. Puliti, P.I. Rossi, G. Caridi, A. Corbelli, M. Ikehata, and S. Armelloni Albuminuria and glomerular damage in mice lacking the metabotropic glutamate receptor 1 American Journal of Pathology 178 March (3) 2011 1257 1269
43. H. Putaala, K. Sainio, H. Sariola, and K. Tryggvason Primary structure of mouse and rat nephrin cDNA and structure and expression of the mouse gene Journal of the American Society of Nephrology 11 June (6) 2000 991 1001
44. H. Putaala, R. Soininen, P. Kilpeläinen, J. Wartiovaara, and K. Tryggvason The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death Human Molecular Genetics 10 January (1) 2001 1 8
45. M.P. Rastaldi, S. Armelloni, S. Berra, N. Calvaresi, A. Corbelli, and L.A. Giardino Glomerular podocytes contain neuron-like functional synaptic vesicles FASEB Journal 20 2006 976 978
46. K.J. Reidy, G. Villegas, J. Teichman, D. Veron, W. Shen, and J. Jimenez Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development Development 136 2009 3979 3989
47. A. Saito, N. Miyauchi, T. Hashimoto, T. Karasawa, G.D. Han, and M. Kayaba Neurexin-1, a presynaptic adhesion molecule, localizes at the slit diaphragm of the glomerular podocytes in kidneys American Journal of Physiology Regulatory, Integrative and Comparative Physiology 300 2011 R340 R348
48. L.D. Stegink, L.J. Filer Jr., and G.L. Baker Plasma amino acid concentrations in normal adults ingesting aspartame and monosodium l-glutamate as part of a soup/beverage meal Metabolism: Clinical and Experimental 36 November (11) 1987 1073 1079
49. O. Stettler, K.L. Moya, A. Zahraoui, and B. Tavitian Developmental changes in the localization of the synaptic vesicle protein rab3A in rat brain Neuroscience 62 1994 587 600
50. K. Takano, Y. Kawasaki, T. Imaizumi, H. Matsuura, R. Nozawa, and M. Tannji Development of glomerular endothelial cells, podocytes and mesangial cells in the human fetus and infant Tohoku Journal of Experimental Medicine 212 May (1) 2007 81 90
51. N. Vitureira, R. Andrés, E. Pérez-Martínez, A. Martínez, A. Bribián, and J. Blasi Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation PLoS ONE 5 2010 e12003
52. X. Wang, Q. Wang, S. Yang, M. Bucan, M.M. Rich, and K.L. Engisch Impaired activity-dependent plasticity of quantal amplitude at the neuromuscular junction of Rab3A deletion and Rab3A earlybird mutant mice Journal of Neuroscience 31 2011 3580 3588
53. N. Wanner, F. Noutsou, R. Baumeister, G. Walz, T.B. Huber, and E. Neumann-Haefelin Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis PLoS ONE 6 2011 e23598
54. J. Wartiovaara, L.G. Ofverstedt, J. Khoshnoodi, J. Zhang, E. Mäkelä, and S. Sandin Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography Journal of Clinical Investigation 114 November (10) 2004 1475 1483
55. R. Willecke, J. Heuberger, K. Grossmann, O. Michos, K. Schmidt-Ott, and K. Walentin The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney Developmental Biology 360 2011 310 317
56. C.Y. Xing, M.A. Saleem, R.J. Coward, L. Ni, I.R. Witherden, and P.W. Mathieson Direct effects of dexamethasone on human podocytes Kidney International 70 2006 1038 1045
57. E. Yaoita, N. Sato, Y. Yoshida, M. Nameta, and T. Yamamoto Cadherin and catenin staining in podocytes in development and puromycin aminonucleoside nephrosis Nephrology, Dialysis, Transplantation 17 Suppl. 9 2002 16 19
58. E. Yaoita, H. Kurihara, Y. Yoshida, T. Inoue, A. Matsuki, and T. Sakai Role of Fat1 in cell-cell contact formation of podocytes in puromycin aminonucleoside nephrosis and neonatal kidney Kidney International 68 August (2) 2005 542 551