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Volumn 20, Issue 20, 2012, Pages 6089-6096

Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors

Author keywords

4,5 Dihydropyrazole; Antitumor activity; BRAF inhibitor; Synthesis

Indexed keywords

1 [3 (4 BROMOPHENYL) 5 (3,5 DIBROMO 2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [3 (4 BROMOPHENYL) 5 (3,5 DICHLORO 2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [3 (4 BROMOPHENYL) 5 (5 CHLORO 2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [3 (4 CHLOROPHENYL) 5 (3,5 DIBROMO 2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [3 (4 CHLOROPHENYL) 5 (3,5 DICHLORO 2 HYDROXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DIBROMO 2 HYDROXYPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DIBROMO 2 HYDROXYPHENYL) 3 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DIBROMO 2 HYDROXYPHENYL) 3 (PARA TOLYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DICHLORO 2 HYDROXYPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DICHLORO 2 HYDROXYPHENYL) 3 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (3,5 DICHLORO 2 HYDROXYPHENYL) 3 (PARA TOLYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 BROMO 2 HYDROXYPHENYL) 3 (4 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 BROMO 2 HYDROXYPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 BROMO 2 HYDROXYPHENYL) 3 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 BROMO 2 HYDROXYPHENYL) 3 (PARA TOLYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 CHLORO 2 HYDROXYPHENYL) 3 (4 BROMOPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 CHLORO 2 HYDROXYPHENYL) 3 (4 CHLOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 CHLORO 2 HYDROXYPHENYL) 3 (4 FLUOROPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 CHLORO 2 HYDROXYPHENYL) 3 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 1 [5 (5 CHLORO 2 HYDROXYPHENYL) 3 (PARA TOLYL) 4,5 DIHYDRO 1H PYRAZOL 1 YL]ETHANONE; 2 [4 (2 DIMETHYLAMINOETHOXY)PHENYL] 4 (1 HYDROXYIMINO 5 INDANYL) 5 (4 PYRIDINYL) 1H IMIDAZOLE; 4,5 DIHYDRO 2H PYRAZOLE 2 HYDROXYPHENYL DERIVATIVE; B RAF KINASE INHIBITOR; ERLOTINIB; UNCLASSIFIED DRUG;

EID: 84866941125     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.08.020     Document Type: Article
Times cited : (29)

References (38)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.