Coupling between Catalytic Loop Motions and Enzyme Global Dynamics

PLoS Computational Biology

Volumn 8, Issue 9, 2012, Pages

  Kurkcuoglu, Zeynep ^a   Bakan, Ahmet ^b   Kocaman, Duygu ^a   Bahar, Ivet ^b   Doruker, Pemra ^a  

^a BOGAZICI UNIVERSITY   (Turkey)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRINCIPAL COMPONENT ANALYSIS;

ACTIVE SITE; CRYSTALS STRUCTURES; DIFFERENT SIZES; ELASTIC NETWORK MODELS; GLOBAL DYNAMICS; LOCAL MOTIONS; OLIGOMERIZATIONS; PRINCIPAL-COMPONENT ANALYSIS; SUBSTRATE RECOGNITION; SUBSTRATE-BINDING;

ENZYMES;

3 DEHYDROQUINATE DEHYDRATASE; BETA 1,4 GALACTOSYLTRANSFERASE; BISPHOSPHATE ALDOLASE; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GALACTOSYLTRANSFERASE; HHAI METHYLTRANSFERASE; LACTATE DEHYDROGENASE; METHYLTRANSFERASE; MUTASE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; PROTEIN TYROSINE PHOSPHATASE; PYRUVATE MUTASE; TRIOSEPHOSPHATE ISOMERASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYTIC LOOP MOTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME GLOBAL DYNAMICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; OLIGOMERIZATION; PRINCIPAL COMPONENT ANALYSIS; STATISTICAL MODEL;

EID: 84866924167     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002705     Document Type: Article

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