Protein conformational dynamics in the mechanism of HIV-1 protease catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 52, 2011, Pages 20982-20987

  Torbeev, Vladimir Yu ^a,b   Raghuraman, H ^a,b   Hamelberg, Donald ^c   Tonelli, Marco ^d   Westler, William M ^d   Perozo, Eduardo ^a,b   Kent, Stephen B H ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

^d National Magnetic Resonance Facility at Madison   (United States)

Author keywords

Enzyme catalysis; Hiv protease; Protein dynamics; Protein nmr

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ISOMERIZATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STEADY STATE; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; ELECTRON SPIN RESONANCE SPECTROSCOPY; HIV PROTEASE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84855486395     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1111202108     Document Type: Article

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