메뉴 건너뛰기




Volumn 21, Issue 6, 2012, Pages 569-575

Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma

Author keywords

Methylation; Nasopharyngeal carcinoma; Protocadherin8; Tumor suppressor gene

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; PROTOCADHERIN 8; TRICHOSTATIN A; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84866896681     PISSN: 09598278     EISSN: 14735709     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e328350b097     Document Type: Article
Times cited : (36)

References (30)
  • 1
    • 34250310905 scopus 로고    scopus 로고
    • The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas
    • Chan SL, Cui Y, Van Hasselt A, Li H, Srivastava G, Jin H, et al. (2007). The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Lab Invest 87:644-650.
    • (2007) Lab Invest , vol.87 , pp. 644-650
    • Chan, S.L.1    Cui, Y.2    Van Hasselt, A.3    Li, H.4    Srivastava, G.5    Jin, H.6
  • 2
    • 77955728660 scopus 로고    scopus 로고
    • KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas
    • Cheng Y, Geng H, Cheng SH, Liang P, Bai Y, Li J, et al. (2010). KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Res 70:6516-6526.
    • (2010) Cancer Res , vol.70 , pp. 6516-6526
    • Cheng, Y.1    Geng, H.2    Cheng, S.H.3    Liang, P.4    Bai, Y.5    Li, J.6
  • 3
    • 77953947951 scopus 로고    scopus 로고
    • Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma
    • Haruki S, Imoto I, Kozaki K, Matsui T, Kawachi H, Komatsu S, et al. (2010). Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma. Carcinogenesis 31:1027-1036.
    • (2010) Carcinogenesis , vol.31 , pp. 1027-1036
    • Haruki, S.1    Imoto, I.2    Kozaki, K.3    Matsui, T.4    Kawachi, H.5    Komatsu, S.6
  • 4
    • 33646422462 scopus 로고    scopus 로고
    • Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers
    • Imoto I (2006). Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers. Cancer Res 66:4617-4626.
    • (2006) Cancer Res , vol.66 , pp. 4617-4626
    • Imoto, I.1
  • 5
    • 34648817483 scopus 로고    scopus 로고
    • Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas
    • Jin H, Wang X, Ying J, Wong AHY, Li H, Lee KY, et al. (2007). Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas. Oncogene 26:7490-7498.
    • (2007) Oncogene , vol.26 , pp. 7490-7498
    • Jin, H.1    Wang, X.2    Ying, J.3    Wong, A.H.Y.4    Li, H.5    Lee, K.Y.6
  • 6
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB (2007). The epigenomics of cancer. Cell 128:683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 8
    • 77956525903 scopus 로고    scopus 로고
    • Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma
    • Leshchenko VV, Kuo PY, Shaknovich R, Yang DT, Gellen T, Petrich A, et al. (2010). Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood 116:1025-1034.
    • (2010) Blood , vol.116 , pp. 1025-1034
    • Leshchenko, V.V.1    Kuo, P.Y.2    Shaknovich, R.3    Yang, D.T.4    Gellen, T.5    Petrich, A.6
  • 9
    • 2442540470 scopus 로고    scopus 로고
    • Focus on nasopharyngeal carcinoma
    • Lo KW, To KF, Huang DP (2004). Focus on nasopharyngeal carcinoma. Cancer Cell 5:423-428.
    • (2004) Cancer Cell , vol.5 , pp. 423-428
    • Lo, K.W.1    To, K.F.2    Huang, D.P.3
  • 10
    • 35548999252 scopus 로고    scopus 로고
    • Protocadherin family: Diversity, structure, and function
    • Morishita H, Yagi T (2007). Protocadherin family: diversity, structure, and function. Curr Opin Cell Biol 19:584-592.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 584-592
    • Morishita, H.1    Yagi, T.2
  • 11
    • 79953062931 scopus 로고    scopus 로고
    • Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma
    • Morris MR, Ricketts CJ, Gentle D, McRonald F, Carli N, Khalili H, et al. (2010). Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma. Oncogene 30:1390-1401.
    • (2010) Oncogene , vol.30 , pp. 1390-1401
    • Morris, M.R.1    Ricketts, C.J.2    Gentle, D.3    McRonald, F.4    Carli, N.5    Khalili, H.6
  • 12
    • 70349324480 scopus 로고    scopus 로고
    • Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer
    • Narayan G, Scotto L, Neelakantan V, Kottoor SH, Wong AHY, Loke S-L, et al. (2009). Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer. Genes, Chromosomes Cancer 48:983-992.
    • (2009) Genes, Chromosomes Cancer , vol.48 , pp. 983-992
    • Narayan, G.1    Scotto, L.2    Neelakantan, V.3    Kottoor, S.H.4    Wong, A.H.Y.5    Loke, S.-L.6
  • 13
    • 2942737278 scopus 로고    scopus 로고
    • The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma
    • Qiu G-H, Tan LKS, Loh KS, Lim CY, Srivastava G, Tsai S-T, et al. (2004). The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma. Oncogene 23:4793-4806.
    • (2004) Oncogene , vol.23 , pp. 4793-4806
    • Qiu, G.-H.1    Tan, L.K.S.2    Loh, K.S.3    Lim, C.Y.4    Srivastava, G.5    Tsai, S.-T.6
  • 14
    • 33846941189 scopus 로고    scopus 로고
    • The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation
    • Seng TJ, Low JSW, Li H, Cui Y, Goh HK, Wong MLY, et al. (2006). The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. Oncogene 26:934-944.
    • (2006) Oncogene , vol.26 , pp. 934-944
    • Seng, T.J.1    Low, J.S.W.2    Li, H.3    Cui, Y.4    Goh, H.K.5    Wong, M.L.Y.6
  • 15
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • Suzuki H, Gabrielson E, ChenW, Anbazhagan R, Van Engeland M,Weijenberg MP, et al. (2002). A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 31:141-149.
    • (2002) Nat Genet , vol.31 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chenw Anbazhagan, R.3    Van Engeland, M.4    Weijenberg, M.P.5
  • 16
    • 0344980092 scopus 로고    scopus 로고
    • Methylation status of the Epstein-Barr virus major latent promoter C in iatrogenic B cell lymphoproliferative disease: Application of PCR-based analysis
    • Tao Q, Swinnen LJ, Yang J, Srivastava G, Robertson KD, Ambinder RF (1999). Methylation status of the Epstein-Barr virus major latent promoter C in iatrogenic B cell lymphoproliferative disease: application of PCR-based analysis. Am J Pathol 155:619-625.
    • (1999) Am J Pathol , vol.155 , pp. 619-625
    • Tao, Q.1    Swinnen, L.J.2    Yang, J.3    Srivastava, G.4    Robertson, K.D.5    Ambinder, R.F.6
  • 17
    • 0036712913 scopus 로고    scopus 로고
    • Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells
    • Tao Q, Huang H, Geiman TM, Lim CY, Fu L, Qiu GH, et al. (2002). Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet 11:2091-2102.
    • (2002) Hum Mol Genet , vol.11 , pp. 2091-2102
    • Tao, Q.1    Huang, H.2    Geiman, T.M.3    Lim, C.Y.4    Fu, L.5    Qiu, G.H.6
  • 18
    • 34548631786 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: Molecular pathogenesis and therapeutic developments
    • Tao Q, Chan ATC (2007). Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments. Exp Rev Mol Med 9:644-650.
    • (2007) Exp Rev Mol Med , vol.9 , pp. 644-650
    • Tao, Q.1    Chan, A.T.C.2
  • 19
    • 0037067180 scopus 로고    scopus 로고
    • Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes
    • Tsao SW, Wang X, Liu Y, Cheung YC, Feng H, Zheng Z, et al. (2002). Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes. Biochim Biophys Acta 1590:150-158.
    • (2002) Biochim Biophys Acta , vol.1590 , pp. 150-158
    • Tsao, S.W.1    Wang, X.2    Liu, Y.3    Cheung, Y.C.4    Feng, H.5    Zheng, Z.6
  • 20
    • 20444472028 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma
    • Wei WI, Sham JS (2005). Nasopharyngeal carcinoma. Lancet 365:2041-2054.
    • (2005) Lancet , vol.365 , pp. 2041-2054
    • Wei, W.I.1    Sham, J.S.2
  • 21
    • 52049115449 scopus 로고    scopus 로고
    • OPCML Is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation
    • Williams S, Ying Y, Cui Y, Van Hasselt A, Ng KM, Yu J, et al. (2008). OPCML Is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation. PLoS ONE 3:e2990.
    • (2008) PLoS ONE , vol.3
    • Williams, S.1    Ying, Y.2    Cui, Y.3    Van Hasselt, A.4    Ng, K.M.5    Yu, J.6
  • 23
    • 25144510121 scopus 로고    scopus 로고
    • The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors
    • Ying J (2005). The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors. Clin Cancer Res 11:6442-6449.
    • (2005) Clin Cancer Res , vol.11 , pp. 6442-6449
    • Ying, J.1
  • 24
    • 33244483580 scopus 로고    scopus 로고
    • Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation
    • Ying J, Li H, Seng TJ, Langford C, Srivastava G, Tsao SW, et al. (2006). Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene 25:1070-1080.
    • (2006) Oncogene , vol.25 , pp. 1070-1080
    • Ying, J.1    Li, H.2    Seng, T.J.3    Langford, C.4    Srivastava, G.5    Tsao, S.W.6
  • 25
    • 33847379460 scopus 로고    scopus 로고
    • Frequent epigenetic silencing of protocadherin 10 by methylation in multiple haematologic malignancies
    • Ying J, Gao Z, Li H, Srivastava G, Murray PG, Goh HK, et al. (2007). Frequent epigenetic silencing of protocadherin 10 by methylation in multiple haematologic malignancies. Br J Haematol 136:829-832.
    • (2007) Br J Haematol , vol.136 , pp. 829-832
    • Ying, J.1    Gao, Z.2    Li, H.3    Srivastava, G.4    Murray, P.G.5    Goh, H.K.6
  • 26
    • 49649107454 scopus 로고    scopus 로고
    • Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors
    • Yu J, Tao Q, Cheung KF, Jin H, Poon FF, Wang X, et al. (2008a). Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. Hepatology 48:508-518.
    • (2008) Hepatology , vol.48 , pp. 508-518
    • Yu, J.1    Tao, Q.2    Cheung, K.F.3    Jin, H.4    Poon, F.F.5    Wang, X.6
  • 27
    • 58649120820 scopus 로고    scopus 로고
    • Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer
    • e641
    • Yu J, Cheng YY, Tao Q, Cheung KF, Lam CNY, Geng H, et al. (2009). Methylation of protocadherin 10, a novel tumor suppressor, is associated with poor prognosis in patients with gastric cancer. Gastroenterology 136:640-651, .e641.
    • (2009) Gastroenterology , vol.136 , pp. 640-651
    • Yu, J.1    Cheng, Y.Y.2    Tao, Q.3    Cheung, K.F.4    Lam, C.N.Y.5    Geng, H.6
  • 28
    • 49149121975 scopus 로고    scopus 로고
    • PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer
    • Yu JS, Koujak S, Nagase S, Li CM, Su T, Wang X, et al. (2008b). PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer. Oncogene 27:4657-4665.
    • (2008) Oncogene , vol.27 , pp. 4657-4665
    • Yu, J.S.1    Koujak, S.2    Nagase, S.3    Li, C.M.4    Su, T.5    Wang, X.6
  • 29
    • 0036435155 scopus 로고    scopus 로고
    • Epidemiology of nasopharyngeal carcinoma
    • Yu MC, Yuan JM (2002). Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 12:421-429.
    • (2002) Semin Cancer Biol , vol.12 , pp. 421-429
    • Yu, M.C.1    Yuan, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.