Chemical composition of hydroethanolic extracts from Siparuna guianensis, medicinal plant used as anxiolytics in Amazon region

Revista Brasileira de Farmacognosia

Volumn 22, Issue 5, 2012, Pages 1024-1034

  Negri, Giuseppina ^a   de Santi, Daniel ^a   Tabach, Ricardo ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anxiolytic activity; HPLC DAD ESI MS MS; Passiflora incarnata; Siparuna guianensis; Vicenin 2; Vitexin

Indexed keywords

ALCOHOL; ANXIOLYTIC AGENT; APIGENIN 6,8 DI C GLUCOSIDE; FLAVONOID; KAEMPFEROL 3 O PENTOSYL PENTOSIDE 7 O RHAMNOSIDE; KAEMPFEROL 3,7 DI O RHAMNOSIDE; PASSIFLORA INCARNATA EXTRACT; PLANT EXTRACT; QUERCETIN 3 O PENTOSYL PENTOSIDE 7 O RHAMNOSIDE; QUERCETIN 3 O RUTINOSIDE 7 O RHAMNOSIDE; QUERCETIN 3,7 DI O RHAMNOSIDE; SIPARUNA GUIANENSIS EXTRACT; UNCLASSIFIED DRUG; VITEXIN;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; PROTON TRANSPORT; SIPARUNA GUIANENSIS;

EID: 84866886622     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2012005000034     Document Type: Article

References (43)

1. Abad-Garcia B, Berrueta LA, Garmon-Lobato S, Gallo B, Vicente F 2009. A general analytical strategy for the characterization of phenolic compounds in fruit juices by high-performance liquid chromatography with diode array detection coupled to electrospray ionization and triple quadrupole mass spectrometry. J Chromatogr A 1216: 5398-5415.
2. Abranko L, Garcia-Reyes JF, Molina-Diaz A. 2011. In-source fragmentation and accurate mass analysis of multiclass flavonoid conjugates by electrospray ionization timeof-flight mass spectrometry. J Mass Spectrom 46: 478-488.
3. Abourashed EA, Vanderplank J, Khan IA 2003. High-speed extraction and HPLC fingerprinting of medicinal plants-II. Application to Harman alkaloids of genus passiflora. Pharm Biol 41: 100-106.
4. Aguirre-Hernandez E, Gonzalez-Trujano ME, Martinez AL, Moreno J, Kite G, Terrazas T, Soto-Hernandez M 2010. HPLC/MS analysis and anxiolytic-like effect of quercetin and kaempferol flavonoids from Tilia americana var. mexicana. J Ethnopharmacol 127: 91-97.
5. Barbosa PR, Valvassori SS, Bordignon CL, Kappel VD, Martins MR, Gavioli EC, Quevedo J, Reginatto FH 2008. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food 11: 282-288.
6. Birk CD, Provensi G, Gosmann G, Reginatto FH, Schenkel EP 2005. TLC fingerprint of flavonoids and saponins from Passiflora species. J Liq Chromatogr R T 28: 2285-2291.
7. Braz Filho R, Gabriel SJ, Gomes CMR, Gottlieb OR, Bichara MGA, Maia JGS 1976. Oxoaporphine alkaloids from Fusea longifolia and Siparuna guianensis. Phytochemistry 15: 1187-1188.
8. Carlini EA 2003. Plants and the central nervous system. Pharmacol Biochem Be 75: 501-512.
9. Chirinos R, Betalleluz-Pallardel I, Huaman A, Arbizu C, Pedreschi R, Campos D 2009. HPLC-DAD characterisation of phenolic compounds from Andean oca (Oxalis tuberose Mol.) tubers and their contribution to the antioxidant capacity. Food Chem 113: 1243-1251.
10. De Castro PCF, Hoshino A, da Silva JC, Mendes FR 2007. Possible anxiolytic effect of two extracts of Passiflora quadrangularis L. in experimental models. Phytother Res 21: 481-484.
11. Deng J, Zhou YJ, Bai MM, Li HW, Li L 2010. Anxiolytic and sedative activities of Passiflora edulis f. flavicarpa. J Ethnopharmacol 128: 148-153.
12. Dhawan K, Dhawan S, Sharma A 2004. Passiflora: a review update. J Ethnopharmacol 94: 1-23.
13. Elsas SM, Rossi DJ, Raber J, White G, Seeley CA, Gregory WL, Mohr C, Pfankuch T, Soumyanath A 2010. Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine 17: 940-949.
14. Ennaceur A, Michalikova S, van Rensburg R, Chazot PL 2008. Are benzodiazepines really anxiolytic? Evidence from a 3D maze spatial navigation task. Brain Res 188: 136-153.
15. Fernandez SP, Nguyen M, Yow TT, Chu C, Johnston GAR, Hanrahan JR, Chebib M 2009. The flavonoid glycosides, myricitrin, gossypin and naringin exert anxiolytic action in mice. Neurochem Res 34: 1867-1875.
16. Figueirinha A, Paranhos A, Perez-Alonso JJ, Santos-Buelga C, Batista MT 2008. Cymbopogon citratus leaves: Characterisation of flavonoids by HPLC-PDAESI/MS/ MS and an approach to their potential as a source of bioactive polyphenols. Food Chem 110: 718-728.
17. Grundmann O, Nakajima JI, Kamata K, Seo S, Butterweck V 2009. Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system. Phytomedicine 16: 1769-1773.
18. Grundmann O, Wang J, McGregor GP, Butterweck V 2008. Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system. Planta Med 74: 1769-1773.
19. Harris D, Clayton T, Cook J, Sahbaie P, Halliwell RF, Furtmueller R, Huck S, Sieghart W, DeLorey TM 2008. Selective influence on contextual memory: Physiochemical properties associated with selectivity of benzodiazepine ligands at GABA(A) receptors containing the alpha 5 subunit. J Med Chem 51: 3788-3803.
20. Hellstrom J, Sinkkonen J, Karonen M, Mattila P 2007. Isolation and structure elucidation of procyanidin oligomers from saskatoon berries (Amelanchier alnifolia). J Agric Food Chem 55: 157-164.
21. Jager AK, Saaby L 2011. Flavonoids and the CNS. Molecules 16: 1471-1485.
22. Jayaprakasha GK, Ohnishi-Kameyama M, Ono H, Yoshida M, Jaganmohan Rao L 2006. Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity. J Agric Food Chem 54: 1672-1679.
23. Ji HF, Zhang HY 2006. Theoretical evaluation of flavonoids as multipotent agents to combat Alzheimer's disease. J Mol Struc-Theochem 767: 3-9.
24. Kachlicki P, Einhorn J, Muth D, Kerhoas L, Stobiecki M 2008. Evaluation of glycosylation and malonylation patterns in flavonoid glycosides during LC/MS/MS metabolite profiling. J Mass Spectrom 43: 572-586.
25. Kumar S, Sharma A 2006. The anxiolytic constituent of Turnera aphrodisiaca. Pharm Biol 44: 84-90.
26. Leitão GG, El-Adjiss de Melo WAL, Leitão SG, Brown L 2005. Separation of free and glycosylated flavonoids from Siparuna guianensis by gradient and isocratic CCC. J Liq Chromatogr R T 28: 2041-2051.
27. Li HW, Zhou P, Yang QQ, Shen Y, Deng J, Li L, Zhao D 2011. Comparative studies on anxiolytic activities and flavonoid compositions of Passiflora edulis 'edulis' and Passiflora edulis 'flavicarpa'. J Ethnopharmacol 133: 1085-1090.
28. Lolli LF, Sato CM, Romanini CV, de Biaggi VBL, Santos CAM, de Oliveira RMW 2007. Possible involvement of GABA(A)-benzodiazepine receptor in the anxiolytic like effect induced by Passiflora actinia extracts in mice. J Ethnopharmacol 111: 308-314.
29. Melo FHC, Venancio ET, de Sousa DP, Fonteles MMD, de Vasconcelos SMM, Viana GSB, de Sousa FCF 2010. Anxiolytic-like effect of carvacrol (5-isopropyl-2-methylphenol) in mice: involvement with GABAergic transmission. Fund Clin Pharm 24: 437-443.
30. Muller SD, Vasconcelos SB, Coelho M, Biavatti MW 2005. LC and UV determination of flavonoids from Passiflora alata medicinal extracts and leaves. J Pharmaceut Biomed Anal 37: 399-403.
31. Piccinelli AL, Mesa MG, Armenteros DM, Alfonso MA, Arevalo AC, Campone L, Rastrelli L 2008. HPLC-PDAMS and NMR characterization of C-glycosyl flavones in a hydroalcoholic extract of Citrus aurantifolia leaves with antiplatelet activity. J Agric Food Chem 56: 1574-1581.
32. Renner SS, Won HS. 2001. Repeated evolution of doecy from monoecy in Siparunaceae (Laurales). Syst Biol 50: 700-712.
33. Rodrigues E, Tabach R, Galduróz JCF, Negri G 2008. Plants with possible anxiolytic and/or hypnotic effects as indicated by three brazilian cultures-Indian, Afro-Brazilian, and River-Dweller. Stud Nat Prod Chem 35: 549-595.
34. Sena LM, Zucolotto SM, Reginatto FH, Schenkel EP, Montero De Lima TC 2009. Neuropharmacological activity of the pericarp of Passiflora edulis flavicarpa Degener: putative involvement of C-glycosylflavonoids. Exp Biol Med 234: 967-975.
35. Shahat AA, Cuyckens F, Wang W, Abdel-Shafeek KA, Husseiny HA, Apers S, Van Miert S, Pieters L, Vlietinck AJ, Claeys M 2005. Structural characterization of flavonol di-O-glycosides from Farsetia aegyptia by electrospray ionization and collision-induced dissociation mass spectrometry. Rapid Commun Mass Sp 19: 2172-2178.
36. Stahl E 1969. Thin Layer Chromatography. A Laboratory Handbook. Berlin: Springer Verlag.
37. Steinmann D, Ganzera M 2011. Recent advances on HPLC/MS in medicinal plant analysis. J Pharmaceut Biomed Anal 55: 744-757.
38. Valentini CMA, da Silva LE, Maciel EN, Franceschini E, de Sousa PT, Dall'Oglio EL, Coelho MDB 2010. Annual variation of yield and chemical composition of volatile components of Siparuna guianensis Aublet. Quim Nova 33: 1506-1509.
39. Vessecchi R, Lopes NP, Gozzo FC, Dorr FA, Murgu M, Lebre DT, Abreu R, Bustillos OV 2011. Nomenclaturas de espectrometria de massas em língua portuguesa. Quim Nova 34: 1875-1887.
40. Viana FA, Andrade-Neto M, Pouliquen YBM, Uchoa DEA, Sobral MMSZ, de Morais SM 2002. Essential oil of Siparuna guianensis Aublet from the Amazon region of Brazil. J Essent Oil Res 14: 60-62.
41. Wagner H, Bladt S 1996. Plant Drug Analysis. A thin layer chromatography atlas. Berlin: Springer.
42. Wohlmuth H, Penman KG, Pearson T, Lehmann RP 2010. Pharmacognosy and chemotypes of passionflower (Passiflora incarnata L.). Biol Pharm Bull 33: 1015-1018.
43. Xu YK, Yang SP, Liao SG, Zhang H, Lin LP, Ding J, Yue JM 2006. Alkaloids from Gelsemium elegans. J Nat Prod 69: 1347-1350.