Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method

Phytomedicine

Volumn 17, Issue 12, 2010, Pages 940-949

  Elsas, S M ^a   Rossi, D J ^a   Raber, J ^a,b   White, G ^a   Seeley, C A ^a   Gregory, W L ^c   Mohr, C ^a   Pfankuch, T ^a   Soumyanath, A ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c National College of Natural Medicine   (United States)

Author keywords

Elevated plus maze; Epileptic seizure; Flavonoid; GABAA receptor; Passian flower; Passiflora incarnata; Pentylenetetrazol; Rotarod

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; FLAVONOID; PASSIFLORA INCARNATA EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANXIETY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; GABAERGIC TRANSMISSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SYNAPTIC TRANSMISSION;

ANIMALS; ANTICONVULSANTS; ANXIETY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE; MICE, INBRED STRAINS; PASSIFLORA; PENTYLENETETRAZOLE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; TEMPERATURE;

MUS; PASSIFLORA; PASSIFLORA INCARNATA;

EID: 77956614063     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.03.002     Document Type: Article

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