Anxiolytic activity of a phytochemically characterized Passiflora incarnata extract is mediated via the GABAergic system

Planta Medica

Volumn 74, Issue 15, 2008, Pages 1769-1773

  Grundmann, Oliver ^a   Wang, Jie ^a   McGregor, Gerard P ^b   Butterweck, Veronika ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b Pascoe Pharmaceutical Preparations GmbH   (Germany)

Author keywords

5 HT1A receptor; Anxiolytic effect; Benzodiazepines; Elevated plus maze open field; GABA receptor; Passiflora incarnata; Passifloraceae

Indexed keywords

DIAZEPAM; FLAVONOID; FLUMAZENIL; ISOORIENTIN; ISOVITEXIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ORIENTIN; PASSIFLORA INCARNATA EXTRACT; VITEXIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG IDENTIFICATION; DRUG MECHANISM; GABAERGIC SYSTEM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MAZE TEST; MEDICINAL PLANT; MOUSE; NONHUMAN; PASSIFLORA INCARNATA; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; BUSPIRONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIAZEPAM; FLAVONOIDS; FLUMAZENIL; GABA MODULATORS; MAZE LEARNING; MICE; MICE, INBRED C57BL; PASSIFLORA; PHYTOTHERAPY; PIPERAZINES; PLANT EXTRACTS; PYRIDINES; RECEPTORS, GABA-A; SEROTONIN ANTAGONISTS;

MUS; PASSIFLORA INCARNATA; PASSIFLORACEAE;

EID: 58049199482     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1088322     Document Type: Article

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