Apigenin: The anxiolytic constituent of Turnera aphrodisiaca

Pharmaceutical Biology

Volumn 44, Issue 2, 2006, Pages 84-90

  Kumar, Suresh ^a   Sharma, Anupam ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Anxiolytic; Aphrodisiac; Apigenin; Turnera aphrodisiaca; Turneraceae

Indexed keywords

ANXIOLYTIC AGENT; APIGENIN; METHANOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; FEMALE; FRACTIONATION; MALE; MAZE TEST; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANQUILIZING ACTIVITY; TURNERA APHRODISIACA; ULTRAVIOLET SPECTROSCOPY;

ANIMALIA; TURNERA DIFFUSA; TURNERACEAE;

EID: 33645058889     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200600591758     Document Type: Article

References (32)

1. Aguilara FJA, Ramos RR, Gutirrez SP, Contretras AA, Weber CCC, Saenz JLF (1998): Study of the anti-hyperglycaemic effect of plants used as antidiabetics. J Ethnopharmacol 61: 101-110.
2. Arletti R, Benelli A, Cavazzuti E, Scarpetta G, Bertolini A (1999): Stimulating property of Turnera diffusa and Pfaffia paniculata extracts on the sexual behavior of male rats. Psychopharmacology 143: 15-19.
3. Auterhoff H, Hackle HP (1968): Components of Damiana drug. Arch Pharm 301: 537-544.
4. Baldessarini R (2001): Drugs and the treatment of psychiatric disorders. In: Hardman JG, Limbird LE, eds., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th ed. New York, McGraw-Hill, pp. 399-427.
5. Boericke W (1988): Pocket Manual of Homoeopathic Materia Medica. New Delhi, India, B. Jain Publisher Private Limited, p. 659.
6. British Herbal Pharmacopoeia (1983): Monograph: Turnera diffusa. West Yorks, British Herbal Medicine Association, p. 29. Available at www.phytotherapies.org/monograph_detail.cfm?id=222
7. Caceres A (1996): Damiana. In: Giron L, Caceres A, eds., Plantas de Uso Medicinal en Guatemala, Ist Ed. Editorial Universataria San Carlos de Guatemala, pp. 160-162.
8. Council Report (1997): Benzodiazepines: Risks, benefits or dependence. London, Royal College of Psychiatrists, London, pp. 1-10. Available at www.rcpsych.ac.uk/publications/cr/council/cr59.pdf
9. Dhawan BN (1995): Centrally acting agents from Indian plants. In: Koslovo SH, Srinivasa MR, Coelho GV, eds., Decade of the Brain: India/USA Research in Mental Health and Neurosciences. Rockville, MD, National Institute of Mental Health, pp. 197-202.
10. Dhawan K, Kumar S, Sharma A (2001a): Comparative biological activity study on Passiflora incarnata and P. edulis. Fitoterapia 72: 698-702.
11. Dhawan K, Kumar S, Sharma A (2001b): Anxiolytic activity of aerial and underground parts of Passiflora incarnata. Fitoterapia 72: 922-926.
12. Dhawan K, Kumar S, Sharma A (2001c): Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. J Ethnopharmacol 78: 165-170.
13. Dominguez XA, Hinojosa M (1976): Mexican medicinal plants. XXVIII. Isolation of 5-hydroxy-7, 3′ 4′-trimethoxy flavone from Turner a diffusa. Planta Med 30: 68-71.
14. Farnsworth NR (1966): Biological and phytochemical screening of plants. J Pharm Sci 55: 225-286.
15. Fryer FA (1965): Chemical investigation of damiana (Turnera diffusa). Specialities 1: 21-23.
16. Hocking GM (1955): A Dictionary of Terms in Pharmacognosy and Other Divisions of Economic Botany. Springfield, IL, Charles C. Thomas, p. 234.
17. Koch L (1936): Drug collection from Bolivia systematically, anatomically and chemically examined. Arch Pharmacol 274: 343-369.
18. Kulkarni SK (2003): Handbook of Experimental Pharmacology, 3rd ed. Pitampura, New Delhi, Vallabh Prakashan, pp. 135-140.
19. Kumar S, Sharma A (2004): Anti-anxiety activity studies of various extracts of Turnera aphrodisiaca Ward. J Herbal Pharmacother 5: 13-21.
20. Longo L, Johnson B (2000): Addiction: Part I. Benzodiazepines-side effects, abuse risk and alternatives. Am Fam Physician 61: 2121-2128. Available at http://ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db= Pubmed&list_uids=10779253&dopt=Abstract
21. Mabry T, Markham K, Thomas M (1970). The Systematic Identification of Flavonoids. New York, Springer-Verlag, pp. 81, 280.
22. NIMH (2002): Anxiety Disorders. Bethesda, MD, National Institute of Mental Health, Office of Communications and Public Liaison.
23. Osol A, Farrar GF, Leuallen EE, Youngken HW, Detweiler DK (1947): Dispensatory of United States of America, 24th ed. Philadelphia, J. B. Lippincott Company, pp. 1422-1423.
24. Owen RW, Haubner R, Mier W, Giacosa A, Hull WE, Spiegelhalder B, Bartsch H (2003): Isolation, structure elucidation and antioxidant potential of the major phenolic and flavonoid compounds in brined olive drupes. Food Chem Toxicol 41: 703-717.
25. Parfitt K (1999): Martindale, the Complete Drug Reference, 32nd ed. London, Pharmaceutical Press, p. 1570.
26. Perez RM, Ocegueda A, Munoz JL, Avita JG, Morrow WW (1984): A study of the hypoglycaemic effect of some Mexican plants. J Ethnopharmacol 12: 253-262.
27. Saggese D (1959): Medicinal Herbs of Argentina, 10th ed. Argentina, Antoghazzi & Co., Rosario Argentina, pp. 1-189.
28. Salgueiro JB, Ardenghi P, Dias M, Perreira MBC, Izquierdo I, Medina JH (1997): Anxiolytic natural and synthetic flavonoid ligands of the central benzodiazepine receptor have no effect on memory tasks in rats. Pharmacol Biochem Behav 58: 887-891.
29. Scheffer WC (1980): Statistics for the Biological Sciences. Reading, MA, Addison-Wesley, pp. 121-141.
30. Spencer KC, Seigler DS (1981): Tetraphyllin B from Turnera diffusa. Planta Med 43: 175-178.
31. Steinmetz EF (1960): Damianae folia. Acta Phytotherapeut 7: 1-2.
32. Viola H, Wasowski C, Stein MLd, Wolfman C, Silveira R, Dajas F, Medina JH, Paladini AC (1995): Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepines receptors-ligand with anxiolytic effects. Planta Med 61: 213-216.