Non-genetic mechanisms communicating antibiotic resistance: Rethinking strategies for antimicrobial drug design

Expert Opinion on Drug Discovery

Volumn 7, Issue 10, 2012, Pages 923-933

  El Halfawy, Omar M ^a,b   Valvano, Miguel A ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Antimicrobial peptides; Antimicrobial therapy; Epigenetics; Indol; Intrinsic resistance; Opportunistic bacteria; Polyamines

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CARBENICILLIN; CEFOTAXIME; CHLORAMPHENICOL; CIPROFLOXACIN; COLISTIN; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; IMIPENEM; KANAMYCIN; MACROLIDE; NALIDIXIC ACID; NETILMICIN; NORFLOXACIN; NOVOBIOCIN; PENICILLIN G; POLYAMINE; POLYMYXIN B; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RHODAMINE 6G; RIFAMPICIN; SPECTINOMYCIN; TETRACYCLINE; TRIMETHOPRIM; UNINDEXED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIUM ISOLATE; BIOSYNTHESIS; DRUG DESIGN; GENE TRANSFER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; QUORUM SENSING; REVIEW; SIGNAL TRANSDUCTION;

ANTI-BACTERIAL AGENTS; BACTERIA; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; HUMANS;

EID: 84866883403     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2012.712512     Document Type: Review

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