A Phase II study of pulse dose imatinib mesylate and weekly paclitaxel in patients aged 70 and over with advanced non-small cell lung cancer

BMC Cancer

Volumn 12, Issue , 2012, Pages

  Bauman, Julie E ^a,f   Eaton, Keith D ^b   Wallace, Sarah G ^b   Carr, Laurie L ^c   Lee, Sang Joon ^a,g   Jones, Dennie V ^d   Arias Pulido, Hugo ^a   Cerilli, Lisa A ^e   Martins, Renato G ^b  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c DEPARTMENT OF MEDICINE   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^g Celltrion Inc   (South Korea)

Author keywords

Elderly; Frailty; Imatinib mesylate; Interstitial fluid pressure; Non small cell lung cancer; Paclitaxel; Platelet derived growth factor; Vulnerable elder survey

Indexed keywords

BILIRUBIN; IMATINIB; PACLITAXEL; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ADVANCED CANCER; AGED; ANEMIA; ARTICLE; BLADDER STONE; CANCER COMBINATION CHEMOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; CONSTIPATION; DIARRHEA; DRUG DOSE REDUCTION; EDEMA; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; FRAIL ELDERLY; FUNCTIONAL STATUS; HEART ARREST; HEART INFARCTION; HUMAN; HUMAN TISSUE; INFECTION; LUNG EMBOLISM; LUNG NON SMALL CELL CANCER; MALE; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NEPHROLITHIASIS; NEUTROPENIA; OPEN STUDY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; PNEUMONIA; PNEUMOTHORAX; PREDICTION; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; SIDE EFFECT; SURVIVAL RATE; SURVIVAL TIME; SYSTOLIC DYSFUNCTION; THROMBOCYTOPENIA; TREATMENT RESPONSE; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG ANTAGONISM; DRUG EFFECT; LUNG; LUNG TUMOR; METABOLISM; PATHOLOGY; REMISSION; SIGNAL TRANSDUCTION; SURVIVAL; TREATMENT OUTCOME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BENZAMIDES; CARCINOMA, NON-SMALL-CELL LUNG; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FATIGUE; FEMALE; FRAIL ELDERLY; HUMANS; LUNG; LUNG NEOPLASMS; MALE; NEOPLASM STAGING; NEUTROPENIA; PACLITAXEL; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-SIS; PYRIMIDINES; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; REMISSION INDUCTION; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84866863451     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-12-449     Document Type: Article

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