Experimental results from a preclinical X-ray phase-contrast CT scanner

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 39, 2012, Pages 15691-15696

  Tapfer, Arne ^a   Bech, Martin ^a,b   Velroyen, Astrid ^a   Meiser, Jan ^c   Mohr, Jürgen ^c   Walter, Marco ^d   Schulz, Joachim ^d   Pauwels, Bart ^e   Bruyndonckx, Peter ^e   Liu, Xuan ^e   Sasov, Alexander ^e   Pfeiffer, Franz ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b LUND UNIVERSITY   (Sweden)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^d MICROWORKS GMBH   (Germany)

^e Bruker MicroCT ^*  (Belgium)

Author keywords

Differential X ray phase contrast; Grating interferometer; X ray imaging

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFACT; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST; FEASIBILITY STUDY; GRATING; IMAGE ANALYSIS; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIGNAL NOISE RATIO; SOFT TISSUE; SWINE; X RAY; X RAY PHASE CONTRAST COMPUTED TOMOGRAPHY;

ANIMALS; HUMANS; MODELS, THEORETICAL; TOMOGRAPHY, X-RAY COMPUTED;

ANIMALIA;

EID: 84866846530     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1207503109     Document Type: Article

References (27)

1. Fitzgerald R (2000) Phase-sensitive x-ray imaging. Phys Today 53:23-26.
2. David C, Nohammer B, Solak H, Ziegler E (2002) Differential X-ray phase contrast imaging using a shearing interferometer. Appl Phys Lett 81:3287-3289.
3. Momose A, et al. (2003) Demonstration of X-Ray Talbot Interferometry. Jpn J Appl Phys 42:L866-L868.
4. Momose A (2005) Recent advances in X-ray phase imaging. Jpn J Appl Phys 44:6355-6367.
5. Weitkamp T, et al. (2005) X-ray phase imaging with a grating interferometer. Opt Express 13:6296-6304. (Pubitemid 41218520)
6. Herzen J, et al. (2009) Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source. Opt Express 17:622-628.
7. Qi Z, Zambelli J, Bevins N, Chen G (2010) Quantitative imaging of electron density and effective atomic number using phase contrast CT. Phys Med Biol 55:2669-2677.
8. Tapfer A, et al. (2011) Development of a prototype gantry system for preclinical x-ray phase-contrast computed tomography. Med Phys 38:5910-5915.
9. Pfeiffer F, Weitkamp T, Bunk O, David C (2006) Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources. Nat Phys 2:258-261. (Pubitemid 43553647)
10. Weitkamp T, David C, Kottler C, Bunk O, Pfeiffer F (2006) Tomography with grating interferometers at low-brilliance sources. Proc SPIE 6318:63180S.
11. Bech M, et al. (2009) Soft-tissue phase-contrast tomography with an x-ray tube source. Phys Med Biol 54:2747-2753.
12. Donath T, et al. (2010) Toward clinical X-ray phase-contrast CT: Demonstration of enhanced soft-tissue contrast in human specimen. Invest Radiol 45:445-452.
13. Stampanoni M, et al. (2011) The first analysis and clinical evaluation of native breast tissue using differential phase-contrast mammography. Invest Radiol 46:801-806.
14. Stutman D, Beck TJ, Carrino Ja, Bingham CO (2011) Talbot phase-contrast x-ray imaging for the small joints of the hand. Phys Med Biol 56:5697-5720.
15. Jerjen I, et al. (2010) Phase contrast cone beam tomography with an X-ray grating interferometer. In AIP Conference Proceedings, Vol 1236 pp:227-231.
16. Thuering T, et al. (2011) High resolution, large field of view x-ray differential phase contrast imaging on a compact setup. Appl Phys Lett 99:041111.
17. Revol V, et al. (2011) X-ray interferometer with bent gratings: Towards larger fields of view. Nucl Instrum Methods Phys Res A 648:S302-S305.
18. Pfeiffer F, et al. (2008) Hard-X-ray dark-field imaging using a grating interferometer. Nat Mater 7:134-137. (Pubitemid 351161343)
19. Reznikova E, Mohr J, Boerner M, Nazmov V, Jakobs PJ (2008) Soft X-ray lithography of high aspect ratio SU8 submicron structures. Microsyst Technol 14:1683-1688.
20. Feldkamp L, Davis L, Kress J (1984) Practical conebeam algorithm. J Opt Soc Am A 1:612-619.
21. Pfeiffer F, Kottler C, Bunk O, David C (2007) Hard X-ray phase tomography with low-brilliance sources. Phys Rev Lett 98:1-4.
22. Kak A, Slaney M (1987) Principles of Computerized Tomography (IEEE Press, New York).
23. Hounsfield GN (1973) Computerized transverse axial scanning (tomography): Part 1. Description of system. Br J Radiol 46:1016-1022.
24. James R (1962) The Optical Principles of the Diffraction of X-rays (Ox Bow Press, Woodbridge).
25. Engelhardt M, et al. (2007) High-resolution differential phase contrast imaging using a magnifying projection geometry with a microfocus x-ray source. Appl Phys Lett 90:224101.
26. Donath T, et al. (2009) Inverse geometry for grating-based x-ray phase-contrast imaging. J Appl Phys 106 (Ox Bow Press, Woodbridge, CT) 054703.
27. Berger MJ, et al. (1998) XCOM: Photon Cross Sections Database (National Institute of Standards and Technology, Gaithersburg, MD), Available at http://physics.nist.gov/PhysRefData/Xcom/Text/intro.html. Accessed March 21, 2012.