Hepatitis B virus surface antigen can activate human monocyte-derived dendritic cells by nuclear factor kappa B and p38 mitogen-activated protein kinase mediated signaling

Microbiology and Immunology

Volumn 56, Issue 10, 2012, Pages 719-727

  Jan, Rong Hwa ^a,b   Lin, Yu Li ^c   Chen, Chia Jung ^a   Lin, Teng Yi ^d   Hsu, Ya Chun ^b   Chen, Li Kuang ^a,d   Chiang, Bor Luen ^c  

^a TZU CHI UNIVERSITY   (Taiwan)

^b Hualien Tzu Chi Hospital   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Costimulatory molecules; Dendritic cell; Hepatitis B virus; Major histocompatibility complex class II

Indexed keywords

B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE 13;

ANTIGEN FUNCTION; ARTICLE; CELL MATURATION; CELL SURFACE; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD; CELLS, CULTURED; DENDRITIC CELLS; HEPATITIS B SURFACE ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INTERFERONS; INTERLEUKINS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

HEPATITIS B VIRUS;

EID: 84866793666     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2012.00496.x     Document Type: Article

References (46)

1. Milich D.R. (1997) Pathobiology of acute and chronic hepatitis B virus infection: an introduction. J Viral Hepat 4: 25-30.
2. Akbar S.M., Onji M., Inaba K., Yamamura K.I., Ohta Y. (1993) Low responsiveness of hepatitis B virus-transgenic mice in antibody response to T-cell-dependent antigen: defect in antigen-presenting activity of dendritic cells. Immunology 78: 468-75.
3. Kurose K., Akbar S.M., Yamamoto K., Onji M. (1997) Production of antibody to hepatitis B surface antigen (anti-HBs) by murine hepatitis B virus carriers: neonatal tolerance versus antigen presentation by dendritic cells. Immunology 92: 494-500.
4. Banchereau J., Steinman R.M. (1998) Dendritic cells and the control of immunity. Nature 392: 245-52.
5. Pulendran B., Tang H., and Denning T.L. (2008) Division of labor, plasticity, and cross-talk between dendritic cell subsets. Curr Opin Immunol 20: 61-7.
6. Cella M., Pinet Engering A., Pieters J., Lanzavecchia A. (1997) Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388: 782-7.
7. Jochum C., Voth R., Rossol S. (1990) Immunosuppressive function of hepatitis B antigens in vitro: role of endoribonuclease V as one potential trans inactivator for cytokines in macrophages and human hepatoma cells. J Virol 64: 1956-63.
8. Op den Brouw M.L., Binda R.S., van Roosmalen M.H., Protzer U., Janssen H.L., van der Molen R.G., Woltman A.M. (2009) Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology 126: 280-9.
9. Xu Y., Hu Y., Shi B., Zhang X., Wang J., Zhang Z., Shen F., Zhang Q., Sun S., Yuan Z. (2009) HBsAg inhibits TLR9-mediated activation and IFN-alpha production in plasmacytoid dendritic cells. Mol Immunol 46: 2640-6.
10. Bian G., Cheng Y., Wang Z., Hu Y., Zhang X., Wu M., Chen Z., Shi B., Sun S., Shen Y., Chen E.J., Yao X., Wen Y., Yuan Z. (2009) Whole recombinant Hansenula polymorpha expressing hepatitis B virus surface antigen (yeast-HBsAg) induces potent HBsAg-specific Th1 and Th2 immune responses. Vaccine 28: 187-94.
11. Fazle Akbar S.M., Furukawa S., Yoshida O., Hiasa Y., Horiike N., Onji M. (2007) Induction of anti-HBs in HB vaccine nonresponders in vivo by hepatitis B surface antigen-pulsed blood dendritic cells. J Hepatol 47: 60-6.
12. Jan R.H., Lin Y.L., Chen L.K., Huang M.T., Wang L.C., Chiang B.L. (2011) Hepatitis B virus surface antigen can activate dendritic cells and modulate T helper type immune response. Microbiol Immunol. 55: 51-9.
13. O'Sullivan B.J., Thomas R. (2002) CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB. J Immunol 168: 5491-8.
14. mapk are involved in IL-10-mediated selective repression of TNF-α-induced activation and maturation of human peripheral blood monocyte-derived dendritic cells. J Immunol 162: 3865-72.
15. Ardeshna K.M., Pizzey A.R., Devereux S., Khwaja A. (2000) The PI3 kinase, p38 SAP kinase, and NF-KB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 96: 1039-46.
16. Hildt E., Saher G., Bruss G.V., Hofschneider P.H. (1996) The hepatitis B virus large surface protein (LHBs) is a transcriptional activator. Virology 225: 235-9.
17. Huang Q., Liu D., Majewski P. (2001) The plasticity of dendritic cell responses to pathogens and their components. Science 294: 870-5.
18. Sallusto F., Lanzavecchia A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulation factor plus interleukin 4 and downregulated by tumor necrosis factor α J Exp Med 179: 1109-18.
19. + dendritic cells. Proc Natl Acad Sci USA 93: 2588-92.
20. Lin Y.L., Liang Y.C., Lee S.S., Chiang B.L. (2005) Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-κB and p38 mitogen-activated protein kinase pathways. J Leukoc Biol 78: 533-43.
21. Sallusto F., Cella M., Danieli C., Lanzavecchia A. (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 182: 389-400.
22. Moore K.W., de Waal Malefyt R., Coffman R. L., O'Garra A. (2001) Interleukin-10 and interleukin-10 receptor. Annu Rev Immunol 19: 683-765.
23. Macatonia S.E., Hosken N.A., Litton M. (1995) Dendritic cells produce IL-12 and direct the development of Th1 cells from naïve CD4+ T cells. J Immunol 154: 5071-9.
24. Trinchieri G. (1998) Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv Immunol 70: 83-243.
25. Sinigaglia F., D'Ambrosio D., Panina-Bordignon P., Rogge L. (1999) Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function. Immunol Rev 170: 65-72.
26. Hsieh C.S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., Murphy K.M. (1993) Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 260: 547-9.
27. Hendrzak J.A., Brunda M.J. Interleukin-12 (1995) Biologic activity, therapeutic utility, and role in disease. Lab Invest 72: 619-37.
28. Galon J., Sudarshan C., Ito S., Finbloom D., O'Shea J.J. (1999) IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells. J Immunol 162: 7256-62.
29. Biron C.A., Nguyen K.B., Pien G.C., Cousens L.P., Salazar-Mather T.P. (1999) Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu Rev Immunol 17: 189-220.
30. Heaton T., Rowe J., Turner S. (2005) An immunoepidemiological approach to asthma: identification of in-vitro T cell response patterns associated with different wheezing phenotypes in children. Lancet 365: 142-9.
31. John M., Lim S., Seybold J. (1998) Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1a, granulocyte-macrophage colonu-stimulating factor, and interferon-g release from alveolar macrophages in asthma. Am J Respir Crit Care Med 157: 256-62.
32. Colavita A.M., Hastie A.T., Musani A.I. (2000) Kinetics of IL-10 production after segmental antigen challenge of atopic asthmatic subjects. J Allergy Clin Immunol 106: 880-6.
33. Machida A., Kishimoto S., Ohnuma H., Miyamoto H., Baba K., Oda K., Nakamura T., Miyakawa Y., Mayumi M. (1983) A hepatitis B surface antigen polypeptide (P31) with the receptor for polymerized human as well as chimpanzee albumins. Gastroenterology 85: 268-74.
34. Treichel U., Meyer zum Büschenfelde K.H., Stockert R.J., Poralla T., Gerken G. (1994) The asialoglycoprotein receptor mediates hepatic binding and uptake of natural hepatitis B virus particles derived from viraemic carriers. J Gen Virol 75: 3021-9.
35. Chong W.P., To Y.F., Ip W.K., Yuen M.F., Poon T.P., Wong W.H., Lai C.L., Lau Y.L. (2005) Mannose-binding lectin in chronic hepatitis B virus infection. Hepatology 42: 1037-45.
36. Glebe D., Urban S. (2007) Viral and cellular determinants involved in hepadnaviral entry. World J Gastroenterol 13: 22-38.
37. García-García E., Rosales C. (2002) Signal transduction during Fc receptor-mediated phagocytosis. J Leukoc Biol 72: 1092-108.
38. Ehlers M.R. (2000) CR3: a general purpose adhesion-recognition receptor essential for innate immunity. Microbes Infect 2: 289-94.
39. Hart S.P., Smith J.R., Dransfield I. (2004) Phagocytosis of opsonized apoptotic cells: roles for 'old-fashioned' receptors for antibody and complement. Clin Exp Immunol 135: 181-5.
40. Janeway C.A. Jr (1989) Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 54: 1-13.
41. Ghosh S., May M.J., Kopp E.B. (1998) NF-KB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16: 225-60.
42. Saccani S., Pantano S., Natoli G. (2002) p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 3: 69-75.
43. Escors D., Lopes L., Lin R., Hiscott J., Akira S., Davis R.J., Collins M.K. (2008) Targeting dendritic cell signalling to regulate the response to immunisation. Blood 111: 3050-61
44. Yoshimoto T., Kojima K., Funakoshi T., Endo Y., Fujita T., Nariuchi H. (1996) Molecular cloning and characterization of murine IL-12 genes. J Immunol 156: 1082-88.
45. Foey A.D., Parry S.L., Williams L.M., Feldmann M., Foxwell B.M., Brennan F.M. (1998) Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-α: role of the p38 and p42/44 mitogen-activated protein kinases. J Immunol 160: 920-8.
46. Dodeller F., Schulze-Koops H. (2006) The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells. Arthritis Res Ther 8: 205.