-
1
-
-
0011816721
-
Determining the roles of subunits in protein function
-
Creighton TE, ed Oxford: IRL Press
-
Eisenstein E, Schachman HK. Determining the roles of subunits in protein function. In: Creighton TE, ed. Protein Function. Oxford: IRL Press, 1989.
-
(1989)
Protein Function
-
-
Eisenstein, E.1
Schachman, H.K.2
-
2
-
-
0016844796
-
Self-assembly of biological macromolecules
-
Perham RN. Self-assembly of biological macromolecules. Philos Trans R Soc Lond B Biol Sci 1975; 272(915):123-136.
-
(1975)
Philos Trans R Soc Lond B Biol Sci
, vol.272
, Issue.915
, pp. 123-136
-
-
Perham, R.N.1
-
4
-
-
22944475303
-
Protein oligomerization: How and why
-
Ali MH, Imperiali B. Protein oligomerization: How and why. Bioorg Med Chem 2005; 13(17):5013-5020.
-
(2005)
Bioorg Med Chem
, vol.13
, Issue.17
, pp. 5013-5020
-
-
Ali, M.H.1
Imperiali, B.2
-
5
-
-
0000986242
-
Quaternary structure of proteins
-
Hill RL, ed. New York: Academic Press
-
Klotz IM, Darnall DW, Langerman NR. Quaternary structure of proteins. In: Hill RL, ed. The proteins. New York: Academic Press, 1975.
-
(1975)
The Proteins
-
-
Klotz, I.M.1
Darnall, D.W.2
Langerman, N.R.3
-
6
-
-
0029942954
-
Disruption of the aldolase A tetramer into catalytically active monomers
-
Beernink PT, Tolan DR. Disruption of the aldolase A tetramer into catalytically active monomers. Proc Natl Acad Sci USA 1996; 93(11):5374-5379.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.11
, pp. 5374-5379
-
-
Beernink, P.T.1
Tolan, D.R.2
-
7
-
-
0028230082
-
Dissociation of enzyme oligomers: A mechanism for allosteric regulation
-
Traut TW. Dissociation of enzyme oligomers: a mechanism for allosteric regulation. Crit Rev Biochem Mol Biol 1994; 29(2):125-163.
-
(1994)
Crit Rev Biochem Mol Biol
, vol.29
, Issue.2
, pp. 125-163
-
-
Traut, T.W.1
-
8
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
Monod J, Wyman J, Changeux JP. On the nature of allosteric transitions: a plausible model. J Mol Biol 1965:128-118.
-
(1965)
J Mol Biol
, pp. 128-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
9
-
-
0041312697
-
Diversity of protein-protein interactions
-
Nooren IM, Thornton JM. Diversity of protein-protein interactions. EMBO J 2003; 22(14):3486-3492.
-
(2003)
EMBO J
, vol.22
, Issue.14
, pp. 3486-3492
-
-
Nooren, I.M.1
Thornton, J.M.2
-
11
-
-
16844386953
-
Morphological aspects of oligorneric protein structures
-
Ponstingl H, Thomas KB, Gorse D et al. Morphological aspects of oligorneric protein structures. Prog Biophys Mol Biol 2005; 89(1):9-35.
-
(2005)
Prog Biophys Mol Biol
, vol.89
, Issue.1
, pp. 9-35
-
-
Ponstingl, H.1
Thomas, K.B.2
Gorse, D.3
-
12
-
-
0042868638
-
Role of water mediated interactions in protein-protein recognition landscapes
-
Papoian GA, Ulander J, Wolynes PG. Role of water mediated interactions in protein-protein recognition landscapes. J Am Chem Soc 2003; 125(30):9170-9178.
-
(2003)
J Am Chem Soc
, vol.125
, Issue.30
, pp. 9170-9178
-
-
Papoian, G.A.1
Ulander, J.2
Wolynes, P.G.3
-
13
-
-
0037609791
-
Protein-protein interactions: Structurally conserved residues distinguish between binding sites and exposed protein surfaces
-
Ma B, Elkayam T, Wolfson H et al. Protein-protein interactions: structurally conserved residues distinguish between binding sites and exposed protein surfaces. Proc Natl Acad Sci, USA 2003; 100(10):5772-5777.
-
(2003)
Proc Natl Acad Sci, USA
, vol.100
, Issue.10
, pp. 5772-5777
-
-
Ma, B.1
Elkayam, T.2
Wolfson, H.3
-
14
-
-
0037229456
-
Analysing six types of protein-protein interfaces
-
Ofran Y, Rost B. Analysing six types of protein-protein interfaces. J Mol Biol 2003; 325(2):377-387.
-
(2003)
J Mol Biol
, vol.325
, Issue.2
, pp. 377-387
-
-
Ofran, Y.1
Rost, B.2
-
15
-
-
0030028728
-
Principles of protein-protein interactions
-
Jones S, Thornton JM. Principles of protein-protein interactions. Proc Natl Acad Sci, USA 1996; 93(1):13-20.
-
(1996)
Proc Natl Acad Sci, USA
, vol.93
, Issue.1
, pp. 13-20
-
-
Jones, S.1
Thornton, J.M.2
-
16
-
-
0031565729
-
Analysis of protein-protein interaction sites using surface patches
-
Jones S, Thornton JM. Analysis of protein-protein interaction sites using surface patches. J Mol Biol 1997; 272(1):121-132.
-
(1997)
J Mol Biol
, vol.272
, Issue.1
, pp. 121-132
-
-
Jones, S.1
Thornton, J.M.2
-
17
-
-
0029109468
-
Protein-protein interactions: A review of protein dimer structures
-
Jones S, Thornton JM. Protein-protein interactions: a review of protein dimer structures. Prog Biophys Mol Biol 1995; 63(1):31-65.
-
(1995)
Prog Biophys Mol Biol
, vol.63
, Issue.1
, pp. 31-65
-
-
Jones, S.1
Thornton, J.M.2
-
18
-
-
0003187567
-
The atomic structure of protein-protein recognition sites
-
Lo Conte L, Chothia C, Janin J. The atomic structure of protein-protein recognition sites. J Mol Biol 1999; 285(5):2177-2198.
-
(1999)
J Mol Biol
, vol.285
, Issue.5
, pp. 2177-2198
-
-
Lo Conte, L.1
Chothia, C.2
Janin, J.3
-
19
-
-
0037474541
-
Structural characterisation and functional significance of transient protein-protein interactions
-
Nooren IM, Thornton JM. Structural characterisation and functional significance of transient protein-protein interactions. J Mol Biol 2003; 325(5):991-1018.
-
(2003)
J Mol Biol
, vol.325
, Issue.5
, pp. 991-1018
-
-
Ooren, I.M.1
Thornton, J.M.2
-
20
-
-
0031565725
-
Prediction of protein-protein interaction sites using patch analysis
-
Jones S, Thornton JM. Prediction of protein-protein interaction sites using patch analysis. J Mol Biol 1997; 272(1):133-143.
-
(1997)
J Mol Biol
, vol.272
, Issue.1
, pp. 133-143
-
-
Jones, S.1
Thornton, J.M.2
-
21
-
-
0037832188
-
Computational methods of analysis of protein-protein interactions
-
Salwinski L, Eisenberg D. Computational methods of analysis of protein-protein interactions. Curr Opin Struct Biol 2003; 13(3):377-382.
-
(2003)
Curr Opin Struct Biol
, vol.13
, Issue.3
, pp. 377-382
-
-
Salwinski, L.1
Eisenberg, D.2
-
22
-
-
0038356582
-
Predicted protein-protein interaction sites from local sequence information
-
Ofran Y, Rost B. Predicted protein-protein interaction sites from local sequence information. FEBS Lett 2003; 544(1-3):236-239.
-
(2003)
FEBS Lett
, vol.544
, Issue.1-3
, pp. 236-239
-
-
Ofran, Y.1
Rost, B.2
-
23
-
-
0036721253
-
B rooijmans N, Sharp KA, Kuntz ID
-
B rooijmans N, Sharp KA, Kuntz ID. Stability of macromolecular complexes. Proteins 2002; 48(4):645-653.
-
(2002)
Stability of Macromolecular Complexes. Proteins
, vol.48
, Issue.4
, pp. 645-653
-
-
-
25
-
-
22844439302
-
Insight into the self-association of key enzymes from pathogenic species
-
P erugini MA, Griffin MDW, Smith BJ et al. Insight into the self-association of key enzymes from pathogenic species. Eur Biophys J 2005; 34(5):469-476.
-
(2005)
Eur Biophys J
, vol.34
, Issue.5
, pp. 469-476
-
-
Perugini, M.A.1
Griffin, M.D.W.2
Smith, B.J.3
-
26
-
-
15444366798
-
Novel type of enzyme multimerization enhances substrate affinity of oat beta-glucosidase
-
Kim SY, Kim YW, Hegerl R et al. Novel type of enzyme multimerization enhances substrate affinity of oat beta-glucosidase. J Struct Biol 2005; 150(1):1-10.
-
(2005)
J Struct Biol
, vol.150
, Issue.1
, pp. 1-10
-
-
Kim, S.Y.1
Kim, Y.W.2
Hegerl, R.3
-
27
-
-
0032478746
-
Genetic engineering, production and characterisation of monomeric variants of the dimeric Serratia marcescens endonuclease
-
Franke I, Meiss G, Blecher D et al. Genetic engineering, production and characterisation of monomeric variants of the dimeric Serratia marcescens endonuclease. FEBS Lett 1998; 425(3):517-522.
-
(1998)
FEBS Lett
, vol.425
, Issue.3
, pp. 517-522
-
-
Franke, I.1
Meiss, G.2
Blecher, D.3
-
28
-
-
0025712476
-
Stable, monomeric variants of - Cro obtained by insertion of a designed -hairpin sequence
-
Mossing MC, Sauer RT. Stable, monomeric variants of - Cro obtained by insertion of a designed -hairpin sequence. Science 1990; 250(4988):1712-1715.
-
(1990)
Science
, vol.250
, Issue.4988
, pp. 1712-1715
-
-
Mossing, M.C.1
Sauer, R.T.2
-
29
-
-
0028049318
-
Design, creation and characterization of a stable, monomeric triosephosphate isomerase
-
Borchert TV, Abagyan R, Jaenicke R et al. Design, creation and characterization of a stable, monomeric triosephosphate isomerase. Proc Natl Acad Sci, USA 1994; 91(4):1515-1518.
-
(1994)
Proc Natl Acad Sci, USA
, vol.91
, Issue.4
, pp. 1515-1518
-
-
Borchert, T.V.1
Abagyan, R.2
Jaenicke, R.3
-
30
-
-
0026669091
-
Construction of a stable dimer of Bacillus stearothermophilus lactate dehydrogenase
-
Jackson RM, Gelpi JL, Cortes A et al. Construction of a stable dimer of Bacillus stearothermophilus lactate dehydrogenase. Biochemistry 1992; 31(35):8307-8314.
-
(1992)
Biochemistry
, vol.31
, Issue.35
, pp. 8307-8314
-
-
Jackson, R.M.1
Gelpi, J.L.2
Cortes, A.3
-
31
-
-
0037102362
-
Getting out of shape
-
Dobson CM. Getting out of shape. Nature 2002; 418(6899):729-730.
-
(2002)
Nature
, vol.418
, Issue.6899
, pp. 729-730
-
-
Dobson, C.M.1
-
32
-
-
0035918550
-
Effect of environmental factors on the kinetics of insulin fibril formation: Elucidation of the molecular mechanisms
-
N ielsen L, Khurana R, Coats A et al. Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism. Biochemistry 2001; 40(20):6036-6046.
-
(2001)
Biochemistry
, vol.40
, Issue.20
, pp. 6036-6046
-
-
Nielsen, L.1
Khurana, R.2
Coats, A.3
-
33
-
-
0032558978
-
Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: Implications for wild-type, V30M and L55P amyloid fibril formation
-
Lashuel HA, Lai Z, Kelly JW. Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M and L55P amyloid fibril formation. Biochemistry 1998; 37(51):17851-17864.
-
(1998)
Biochemistry
, vol.37
, Issue.51
, pp. 17851-17864
-
-
Lashuel, H.A.1
Lai, Z.2
Kelly, J.W.3
-
34
-
-
14944368141
-
Kinetic stabilization of the native state by protein engineering: Implications for inhibition of transthyretin amyloidogenesis
-
Foss TR, Kelker MS, Wiseman RL et al. Kinetic stabilization of the native state by protein engineering: Implications for inhibition of transthyretin amyloidogenesis. J Mol Biol 2005; 347(4):841-854.
-
(2005)
J Mol Biol
, vol.347
, Issue.4
, pp. 841-854
-
-
Foss, T.R.1
Kelker, M.S.2
Wiseman, R.L.3
-
35
-
-
29344455729
-
Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alpha(s-) and beta-casein
-
Thorn DC, Meehan S, Sunde M et al. Amyloid fibril formation by bovine milk kappa-casein and its inhibition by the molecular chaperones alpha(s-) and beta-casein. Biochemistry 2005; 44(51):17027-17036.
-
(2005)
Biochemistry
, vol.44
, Issue.51
, pp. 17027-17036
-
-
Thorn, D.C.1
Meehan, S.2
Sunde, M.3
-
36
-
-
0038047044
-
Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN
-
S ouillac PO, Uversky VN, Fink AL. Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN. Biochemistry 2003; 42(26):8094-8104.
-
(2003)
Biochemistry
, vol.42
, Issue.26
, pp. 8094-8104
-
-
Souillac, P.O.1
Uversky, V.N.2
Fink, A.L.3
-
37
-
-
0036544598
-
Inhibition of transthyretin amyloid fibril formation by 2,4-dinitrophenol through tetramer stabilization
-
Raghu P, Reddy GB, Sivakumar B. Inhibition of transthyretin amyloid fibril formation by 2,4-dinitrophenol through tetramer stabilization. Arch Biochem Biophys 2002; 400(1):43-47.
-
(2002)
Arch Biochem Biophys
, vol.400
, Issue.1
, pp. 43-47
-
-
Raghu, P.1
Reddy, G.B.2
Sivakumar, B.3
-
38
-
-
0029982776
-
A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis
-
Jenne DE, Denzel K, Blatzinger P et al. A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis. Proc Natl Acad Sci USA 1996; 93(13):6302-6307.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.13
, pp. 6302-6307
-
-
Jenne, D.E.1
Denzel, K.2
Blatzinger, P.3
-
39
-
-
0038661338
-
D18G transthyretin is monomeric, aggregation prone and not detectable in plasma and cerebrospinal fluid: A prescription for central nervous system amyloidosis?
-
Hammarstrom P, Sekijima Y, White JT et al. D18G transthyretin is monomeric, aggregation prone and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis? Biochemistry 2003; 42(22):6656-6663.
-
(2003)
Biochemistry
, vol.42
, Issue.22
, pp. 6656-6663
-
-
Hammarstrom, P.1
Sekijima, Y.2
White, J.T.3
-
40
-
-
0021381587
-
Properties and metabolism of the aqueous cytoplasm and its boundaries
-
Clegg JS. Properties and metabolism of the aqueous cytoplasm and its boundaries. Am J Physiol 1984; 246(2 Pt 2):R133-151.
-
(1984)
Am J Physiol
, vol.246
, Issue.2 PART 2
-
-
Clegg, J.S.1
-
41
-
-
0037432563
-
Contribution of surface salt bridges to protein stability: Guidelines for protein engineering
-
Makhatadze GI, Loladze VV, Ermolenko DN et al. Contribution of surface salt bridges to protein stability: guidelines for protein engineering. J Mol Biol 2003; 327(5):1135-1148.
-
(2003)
J Mol Biol
, vol.327
, Issue.5
, pp. 1135-1148
-
-
Makhatadze, G.I.1
Loladze, V.V.2
Ermolenko, D.N.3
-
42
-
-
0035448574
-
Ion Pairs and the Thermotolerance of Proteins from Hyperthermophiles: A "traffic rule" for hot roads
-
Karshikoff A, Ladenstein R. Ion pairs and the thermotolerance of proteins from hyperthermophiles: a "traffic rule" for hot roads. Trends Biochem Sci 2001; 26(9):550-556.
-
(2001)
Trends Biochem Sci
, vol.26
, Issue.9
, pp. 550-556
-
-
Karshikoff, A.1
Ladenstein, R.2
-
43
-
-
0032528267
-
Insights into the molecular basis of thermal stability from the analysis of ion-pair networks in the glutamate dehydrogenase family
-
Yip KS, Britton KL, Stillman TJ et al. Insights into the molecular basis of thermal stability from the analysis of ion-pair networks in the glutamate dehydrogenase family. Eur J Biochem 1998; 255(2):336-346.
-
(1998)
Eur J Biochem
, vol.255
, Issue.2
, pp. 336-346
-
-
Yip, K.S.1
Britton, K.L.2
Stillman, T.J.3
-
44
-
-
0034625317
-
Strengthening the dimerisation interface of Lac repressor increases its thermostability by 40C
-
Gerk LP, Leven O, Muller-Hill B. Strengthening the dimerisation interface of Lac repressor increases its thermostability by 40C. J Mol Biol 2000; 299(3):805-812.
-
(2000)
J Mol Biol
, vol.299
, Issue.3
, pp. 805-812
-
-
Gerk, L.P.1
Leven, O.2
Muller-Hill, B.3
-
45
-
-
0032514678
-
Protein thermostability above 100C: A key role for ionic interactions
-
Vetriani C, Maeder DL, Tolliday N et al. Protein thermostability above 100C: a key role for ionic interactions. Proc Natl Acad Sci USA 1998; 95(21):12300-12305.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.21
, pp. 12300-12305
-
-
Vetriani, C.1
Maeder, D.L.2
Tolliday, N.3
-
46
-
-
0033523004
-
Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: Construction of a 16-residue ion-pair network at the subunit interface
-
Lebbink JH, Knapp S, van der Oost J et al. Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface. J Mol Biol 1999; 289(2):357-369.
-
(1999)
J Mol Biol
, vol.289
, Issue.2
, pp. 357-369
-
-
Lebbink, J.H.1
Knapp, S.2
Van Der Oost, J.3
-
47
-
-
2442706372
-
Engineering dimer-stabilizing mutations in the TATA-binding protein
-
Kou H, Pugh BF. Engineering dimer-stabilizing mutations in the TATA-binding protein. J Biol Chem 2004; 279(20):20966-20973.
-
(2004)
J Biol Chem
, vol.279
, Issue.20
, pp. 20966-20973
-
-
Kou, H.1
Pugh, B.F.2
-
48
-
-
0000259836
-
Control of oligomeric enzyme thermostability by protein engineering
-
Ahern TJ, Casal JI, Petsko GA et al. Control of oligomeric enzyme thermostability by protein engineering. Proc Natl Acad Sci USA 1987; 84(3):675-679.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.3
, pp. 675-679
-
-
Ahern, T.J.1
Casal, J.I.2
Petsko, G.A.3
-
49
-
-
0023134941
-
Subunit interface of triosephosphate isomerase: Site-directed mutagenesis and characterization of the altered enzyme
-
Casal JI, Ahern TJ, Davenport RC et al. Subunit interface of triosephosphate isomerase: site-directed mutagenesis and characterization of the altered enzyme. Biochemistry 1987; 26(5):1258-1264.
-
(1987)
Biochemistry
, vol.26
, Issue.5
, pp. 1258-1264
-
-
Casal, J.I.1
Ahern, T.J.2
Davenport, R.C.3
-
50
-
-
0022377520
-
Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface
-
Jones DH, McMillan AJ, Fersht AR et al. Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface. Biochemistry 1985; 24(21):5852-5857.
-
(1985)
Biochemistry
, vol.24
, Issue.21
, pp. 5852-5857
-
-
Jones, D.H.1
McMillan, A.J.2
Fersht, A.R.3
-
51
-
-
0023008210
-
Protein engineering of homodimeric tyrosyl-tRNA synthetase to produce active heterodimers
-
Ward WH, Jones DH, Fersht AR. Protein engineering of homodimeric tyrosyl-tRNA synthetase to produce active heterodimers. J Biol Chem 1986; 261(21):9576-9578.
-
(1986)
J Biol Chem
, vol.261
, Issue.21
, pp. 9576-9578
-
-
Ward, W.H.1
Jones, D.H.2
Fersht, A.R.3
-
52
-
-
0023668284
-
Effects of engineering complementary charged residues into the hydrophobic subunit interface of tyrosyl-tRNA synthetase. Appendix: Kinetic analysis of dimeric enzymes that reversibly dissociate into inactive subunits
-
Ward WH, Jones DH, Fersht AR. Effects of engineering complementary charged residues into the hydrophobic subunit interface of tyrosyl-tRNA synthetase. Appendix: Kinetic analysis of dimeric enzymes that reversibly dissociate into inactive subunits. Biochemistry 1987; 26(13):4131-4138.
-
(1987)
Biochemistry
, vol.26
, Issue.13
, pp. 4131-4138
-
-
Ward, W.H.1
Jones, D.H.2
Fersht, A.R.3
-
53
-
-
0010262095
-
Construction of heterodimer tyrosyl-tRNA synthetase shows tRNATyr interacts with both subunits
-
Carter P, Bedouelle H, Winter G. Construction of heterodimer tyrosyl-tRNA synthetase shows tRNATyr interacts with both subunits. Proc Natl Acad Sci USA 1986; 83(5):1189-1192.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, Issue.5
, pp. 1189-1192
-
-
Carter, P.1
Bedouelle, H.2
Winter, G.3
-
54
-
-
0023709343
-
Recombinant DNA derived monomeric insulin analogue: Comparison with soluble human insulin in normal subjects
-
Vora JP, Owens DR, Dolben J et al. Recombinant DNA derived monomeric insulin analogue: Comparison with soluble human insulin in normal subjects. Bmj 1988; 297(6658):1236-1239.
-
(1988)
Bmj
, vol.297
, Issue.6658
, pp. 1236-1239
-
-
Vora, J.P.1
Owens, D.R.2
Dolben, J.3
-
55
-
-
0023936777
-
Monomeric insulins obtained by protein engineering and their medical implications
-
Brange J, Ribel U, Hansen JF et al. Monomeric insulins obtained by protein engineering and their medical implications. Nature 1988; 333(6174):679-682.
-
(1988)
Nature
, vol.333
, Issue.6174
, pp. 679-682
-
-
Brange, J.1
Ribel, U.2
Hansen, J.F.3
-
56
-
-
0030981739
-
Pharmacokinetic considerations of new insulin formulations and routes of administration
-
H offman A, Ziv E. Pharmacokinetic considerations of new insulin formulations and routes of administration. Clin Pharmacokinet 1997; 33(4):285-301.
-
(1997)
Clin Pharmacokinet
, vol.33
, Issue.4
, pp. 285-301
-
-
Hoffman, A.1
Ziv, E.2
-
57
-
-
0035032976
-
Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics
-
DeFelippis MR, Chance RE, Frank BH. Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics. Crit Rev Ther Drug Carrier Syst 2001; 18(2):201-264.
-
(2001)
Crit Rev Ther Drug Carrier Syst
, vol.18
, Issue.2
, pp. 201-264
-
-
Defelippis, M.R.1
Chance, R.E.2
Frank, B.H.3
-
58
-
-
0030068478
-
Identification of the Serratia endonuclease dimer: Structural basis and implications for catalysis
-
Miller MD, Krause KL. Identification of the Serratia endonuclease dimer: structural basis and implications for catalysis. Protein Sci 1996; 5(1):24-33.
-
(1996)
Protein Sci
, vol.5
, Issue.1
, pp. 24-33
-
-
Miller, M.D.1
Krause, K.L.2
-
59
-
-
0033534445
-
On the advantage of being a dimer, a case study using the dimeric Serratia nuclease and the monomeric nuclease from Anabaena sp. strain PCC 7120
-
Franke I, Meiss G, Pingoud A. On the advantage of being a dimer, a case study using the dimeric Serratia nuclease and the monomeric nuclease from Anabaena sp. strain PCC 7120. J Biol Chem 1999; 274(2):825-832.
-
(1999)
J Biol Chem
, vol.274
, Issue.2
, pp. 825-832
-
-
Franke, I.1
Meiss, G.2
Pingoud, A.3
-
60
-
-
0037418253
-
Retroevolution of lambda Cro toward a stable monomer
-
LeFevre KR, Cordes MHJ. Retroevolution of lambda Cro toward a stable monomer. Proc Natl Acad Sci USA 2003; 100(5):2345-2350.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.5
, pp. 2345-2350
-
-
Lefevre, K.R.1
Cordes, M.H.J.2
-
61
-
-
0027401730
-
Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant
-
Borchert TV, Pratt K, Zeelen JP et al. Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant. Eur J Biochem 1993; 211(3):703-710.
-
(1993)
Eur J Biochem
, vol.211
, Issue.3
, pp. 703-710
-
-
Borchert, T.V.1
Pratt, K.2
Zeelen, J.P.3
-
62
-
-
0029064373
-
An interface point-mutation variant of triosephosphate isomerase is compactly folded and monomeric at low protein concentrations
-
Borchert TV, Zeelen JP, Schliebs W et al. An interface point-mutation variant of triosephosphate isomerase is compactly folded and monomeric at low protein concentrations. FEBS Lett 1995; 367(3):315-318.
-
(1995)
FEBS Lett
, vol.367
, Issue.3
, pp. 315-318
-
-
Borchert, T.V.1
Zeelen, J.P.2
Schliebs, W.3
-
63
-
-
0027146064
-
The crystal structure of an engineered monomeric triosephosphate isomerase, monoTIM: The correct modeling of an 8-residue loop
-
Borchert TV, Abagyan R, Kishan KVR et al. The crystal structure of an engineered monomeric triosephosphate isomerase, monoTIM: the correct modeling of an 8-residue loop. Structure 1993; 1(3):205-213.
-
(1993)
Structure
, vol.1
, Issue.3
, pp. 205-213
-
-
Borchert, T.V.1
Abagyan, R.2
Kvr, K.3
-
64
-
-
33644535470
-
Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor
-
Olivares-Illana V, Perez-Montfort R, Lopez-Calahorra F et al. Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor. Biochemistry 2006; 45(8):2556-2560.
-
(2006)
Biochemistry
, vol.45
, Issue.8
, pp. 2556-2560
-
-
Olivares-Illana, V.1
Perez-Montfort, R.2
Lopez-Calahorra, F.3
-
65
-
-
0037860938
-
Modulation of protein-protein interactions with small organic molecules
-
Berg T. Modulation of protein-protein interactions with small organic molecules. Angew Chem-Int Edit 2003; 42(22):2462-2481.
-
(2003)
Angew Chem-Int Edit
, vol.42
, Issue.22
, pp. 2462-2481
-
-
Berg, T.1
-
66
-
-
23044496736
-
Protein-protein interactions in human disease
-
Ryan DP, Matthews JM. Protein-protein interactions in human disease. Curr Opin Struct Biol 2005; 15(4):441-446.
-
(2005)
Curr Opin Struct Biol
, vol.15
, Issue.4
, pp. 441-446
-
-
Ryan, D.P.1
Matthews, J.M.2
-
67
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
-
Arkin MR, Wells JA. Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream. Nat Rev Drug Discov 2004; 3(4):301-317.
-
(2004)
Nat Rev Drug Discov
, vol.3
, Issue.4
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
68
-
-
0030857332
-
A double mutation at the tip of the dimer interface loop of triosephosphate isomerase generates active monomers with reduced stability
-
Schliebs W, Thanki N, Jaenicke R et al. A double mutation at the tip of the dimer interface loop of triosephosphate isomerase generates active monomers with reduced stability. Biochemistry 1997; 36(32):9655-9662.
-
(1997)
Biochemistry
, vol.36
, Issue.32
, pp. 9655-9662
-
-
Schliebs, W.1
Thanki, N.2
Jaenicke, R.3
-
69
-
-
0029645123
-
Three new crystal structures of point mutation variants of monoTIM: Conformational flexibility of loop-1, loop-4 and loop-8
-
Borchert TV, Kishan KV, Zeelen JP et al. Three new crystal structures of point mutation variants of monoTIM: conformational flexibility of loop-1, loop-4 and loop-8. Structure 1995; 3(7):669-679.
-
(1995)
Structure
, vol.3
, Issue.7
, pp. 669-679
-
-
Borchert, T.V.1
Kishan, K.V.2
Zeelen, J.P.3
-
70
-
-
0029916524
-
Three hTIM mutants that provide new insights on why TIM is a dimer
-
Mainfroid V, Terpstra P, Beauregard M et al. Three hTIM mutants that provide new insights on why TIM is a dimer. J Mol Biol 1996; 257(2):441-456.
-
(1996)
J Mol Biol
, vol.257
, Issue.2
, pp. 441-456
-
-
Mainfroid, V.1
Terpstra, P.2
Beauregard, M.3
-
71
-
-
0029934644
-
Stabilization of human triosephosphate isomerase by improvement of the stability of individual -helices in dimeric as well as monomeric forms of the protein
-
Mainfroid V, Mande SC, Hol WG et al. Stabilization of human triosephosphate isomerase by improvement of the stability of individual -helices in dimeric as well as monomeric forms of the protein. Biochemistry 1996; 35(13):4110-4117.
-
(1996)
Biochemistry
, vol.35
, Issue.13
, pp. 4110-4117
-
-
Mainfroid, V.1
Mande, S.C.2
Hol, W.G.3
-
72
-
-
0025865014
-
Mutated interleukin-5 monomers are biologically inactive
-
McKenzie AN, Ely B, Sanderson CJ. Mutated interleukin-5 monomers are biologically inactive. Mol Immunol 1991; 28(1-2):155-158.
-
(1991)
Mol Immunol
, vol.28
, Issue.1-2
, pp. 155-158
-
-
McKenzie, A.N.1
Ely, B.2
Sanderson, C.J.3
-
73
-
-
0030062246
-
Creation of a biologically active interleukin-5 monomer
-
Dickason RR, Huston DP. Creation of a biologically active interleukin-5 monomer. Nature 1996; 379(6566):652-655.
-
(1996)
Nature
, vol.379
, Issue.6566
, pp. 652-655
-
-
Dickason, R.R.1
Huston, D.P.2
-
74
-
-
0030973204
-
Engineering subunit association of multisubunit proteins: A dimeric streptavidin
-
Sano T, Vajda S, Smith CL et al. Engineering subunit association of multisubunit proteins: a dimeric streptavidin. Proc Natl Acad Sci USA 1997; 94(12):6153-6158.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.12
, pp. 6153-6158
-
-
Sano, T.1
Vajda, S.2
Smith, C.L.3
-
75
-
-
0038154165
-
Dimer-tetramer transition between solution and crystalline states of streptavidin and avidin mutants
-
Pazy Y, Eisenberg-Domovich Y, Laitinen OH et al. Dimer-tetramer transition between solution and crystalline states of streptavidin and avidin mutants. J Bacteriol 2003; 185(14):4050-4056.
-
(2003)
J Bacteriol
, vol.185
, Issue.14
, pp. 4050-4056
-
-
Pazy, Y.1
Eisenberg-Domovich, Y.2
Laitinen, O.H.3
-
76
-
-
0037423398
-
Rational design of an active avidin monomer
-
Laitinen OH, Nordlund HR, Hytonen VP et al. Rational design of an active avidin monomer. J Biol Chem 2003; 278(6):4010-4014.
-
(2003)
J Biol Chem
, vol.278
, Issue.6
, pp. 4010-4014
-
-
Laitinen, O.H.1
Nordlund, H.R.2
Hytonen, V.P.3
-
77
-
-
0032512442
-
Trimeric inorganic pyrophosphatase of Escherichia coli obtained by directed mutagenesis
-
Velichko IS, Mikalahti K, Kasho VN et al. Trimeric inorganic pyrophosphatase of Escherichia coli obtained by directed mutagenesis. Biochemistry 1998; 37(2):734-740.
-
(1998)
Biochemistry
, vol.37
, Issue.2
, pp. 734-740
-
-
Velichko, I.S.1
Mikalahti, K.2
Kasho, V.N.3
-
78
-
-
0033607547
-
Reciprocal effects of substitutions at the subunit interfaces in hexameric pyrophosphatase of Escherichia coli. Dimeric and monomeric forms of the enzyme
-
Salminen A, Efimova IS, Parfenyev AN et al. Reciprocal effects of substitutions at the subunit interfaces in hexameric pyrophosphatase of Escherichia coli. Dimeric and monomeric forms of the enzyme. J Biol Chem 1999; 274(48):33898-33904.
-
(1999)
J Biol Chem
, vol.274
, Issue.48
, pp. 33898-33904
-
-
Salminen, A.1
Efimova, I.S.2
Parfenyev, A.N.3
-
79
-
-
8344234963
-
A monomeric mutant of restriction endonuclease EcoR i nicks DNA without sequence specificity
-
Fritsche P, Alves J. A monomeric mutant of restriction endonuclease EcoR I nicks DNA without sequence specificity. Biol Chem 2004; 385(10):975-985.
-
(2004)
Biol Chem
, vol.385
, Issue.10
, pp. 975-985
-
-
Fritsche, P.1
Alves, J.2
-
80
-
-
16244422033
-
Conversion of the tetrameric restriction endonuclease Bse634I into a dimer: Oligomeric structure-stability-function correlations
-
Zaremba M, Sasnauskas G, Urbanke C et al. Conversion of the tetrameric restriction endonuclease Bse634I into a dimer: Oligomeric structure-stability- function correlations. J Mol Biol 2005; 348(2):459-478.
-
(2005)
J Mol Biol
, vol.348
, Issue.2
, pp. 459-478
-
-
Zaremba, M.1
Sasnauskas, G.2
Urbanke, C.3
-
81
-
-
0032566322
-
Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?
-
Banci L, Benedetto M, Bertini I et al. Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme? Biochemistry 1998; 37(34):11780-11791.
-
(1998)
Biochemistry
, vol.37
, Issue.34
, pp. 11780-11791
-
-
Banci, L.1
Benedetto, M.2
Bertini, I.3
-
82
-
-
0029608758
-
Synthesis and characterization of a monomeric mutant Cu/Zn superoxide dismutase with partially reconstituted enzymic activity
-
Banci L, Bertini I, Chiu CY et al. Synthesis and characterization of a monomeric mutant Cu/Zn superoxide dismutase with partially reconstituted enzymic activity. Eur J Biochem 1995; 234(3):855-860.
-
(1995)
Eur J Biochem
, vol.234
, Issue.3
, pp. 855-860
-
-
Banci, L.1
Bertini, I.2
Chiu, C.Y.3
-
83
-
-
0028128764
-
Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity and oligomerization
-
Porvari KS, Herrala AM, Kurkela RM et al. Site-directed mutagenesis of prostatic acid phosphatase. Catalytically important aspartic acid 258, substrate specificity and oligomerization. J Biol Chem 1994; 269(36):22642-22646.
-
(1994)
J Biol Chem
, vol.269
, Issue.36
, pp. 22642-22646
-
-
Porvari, K.S.1
Herrala, A.M.2
Kurkela, R.M.3
-
84
-
-
0028607161
-
Engineering the quaternary structure of an enzyme: Construction and analysis of a monomeric form of malate dehydrogenase from Escherichia coli
-
Breiter DR, Resnik E, Banaszak LJ. Engineering the quaternary structure of an enzyme: construction and analysis of a monomeric form of malate dehydrogenase from Escherichia coli. Protein Sci 1994; 3(11):2023-2032.
-
(1994)
Protein Sci
, vol.3
, Issue.11
, pp. 2023-2032
-
-
Breiter, D.R.1
Resnik, E.2
Banaszak, L.J.3
-
85
-
-
0028051827
-
Subunit interface mutants of rabbit muscle aldolase form active dimers
-
Beernink PT, Tolan DR. Subunit interface mutants of rabbit muscle aldolase form active dimers. Protein Sci 1994; 3(9):1383-1391.
-
(1994)
Protein Sci
, vol.3
, Issue.9
, pp. 1383-1391
-
-
Beernink, P.T.1
Tolan, D.R.2
-
86
-
-
0029942954
-
Disruption of the aldolase A tetramer into catalytically active monomers
-
Beernink PT, Tolan DR. Disruption of the aldolase A tetramer into catalytically active monomers. Proc Natl Acad Sci USA 1996; 93(11):5374-5379.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.11
, pp. 5374-5379
-
-
Beernink, P.T.1
Tolan, D.R.2
-
87
-
-
0033614008
-
A dimeric form of Escherichia coli succinyl-CoA synthetase produced by site-directed mutagenesis
-
Bailey DL, Fraser ME, Bridger WA et al. A dimeric form of Escherichia coli succinyl-CoA synthetase produced by site-directed mutagenesis. J Mol Biol 1999; 285(4):1655-1666.
-
(1999)
J Mol Biol
, vol.285
, Issue.4
, pp. 1655-1666
-
-
Bailey, D.L.1
Fraser, M.E.2
Bridger, W.A.3
-
88
-
-
45549122274
-
Evolution of quaternary structure in a homotetrameric enzyme
-
Griffin MDW, Dobson RCJ, Pearce FG et al. Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol 2008; 380(4): 691-703.
-
(2008)
J Mol Biol
, vol.380
, Issue.4
, pp. 691-703
-
-
Mdw, G.1
Rcj, D.2
Pearce, F.G.3
|