Inheritance of a mitochondrial DNA defect and impaired glucose tolerance in BHE/Cdb rats

Diabetologia

Volumn 42, Issue 1, 1999, Pages 35-40

  Mathews, C E ^a   McGraw, R A ^b   Dean, R ^b   Berdanier, C D ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Allele specific amplification; BHE Cdb Rat; Competitive PCR; Gene screen; Maternal inheritance; Mitochondrial diabetes; Point mutation

Indexed keywords

MITOCHONDRIAL DNA;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; EXTRACHROMOSOMAL INHERITANCE; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GLUCOSE INTOLERANCE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; RAT;

ANIMALS; BASE SEQUENCE; CROSSES, GENETIC; DNA PRIMERS; DNA, MITOCHONDRIAL; FEMALE; GENOTYPE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTON-TRANSLOCATING ATPASES; RATS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY;

EID: 0005505839     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051109     Document Type: Article

References (25)

1. 1. Berdanier CD (1994) Non-insulin-dependent diabetes in the BHE/Cdb rat. In: Shafrir E (ed) Lessons From Animal Diabetes. Smith-Gordon, London, pp 231-246
2. 2. Mathews CE, McGraw, RA, Berdanier CD (1995) A point mutation in the mitochondrial DNA of diabetes-prone BHE/Cdb rats. FASEB J 9: 1638-1642
3. 3. McCusker RH, Deaver OE, Berdanier CD (1983) Effect of sucrose or starch feeding on hepatic mitochondrial activity of BHE and Wistar rats. J Nutr 113: 1327-1334
4. 4. Deaver OE, Wander RC, McCusker RH, Berdanier CD (1986) Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats. J Nutr 116: 1148-1155
5. 5. Berdanier CD, Thomson AR (1986) Comparative studies on mitochondrial respiration in four strains of rats (rattus novegicus). Comp Biochem Physiol 85B:531-535
6. 6. Liang Y, Bonner-Weir, Wu Y-J et al. (1994) In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents. J Clin Invest 93: 2473-2481
7. 7. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning. A Laboratory Manual. 2nd edn, Cold Spring Harbor, New York
8. 8. Cotton RGH (1992) Detection of single base changes in nucleic acid. Adv Genome Biol 1: 253-300
9. 9. Cotton RGH (1997) Mutation Detection. Oxford University Press, New York, pp 137-142
10. 10. Gibbs RA, Nguyen PN, Caskey CT (1989) Detection of single DNA base differences by competitive oligonucleotide priming. Nucleic Acids Res 17: 2437-2448
11. 11. Sommer SS, Cassady JD, Sobell JL, Bottema CDK (1989) A novel method for detecting point mutations or polymorphisms and its applications to population screening for carriers of phenylketonuria. Mayo Clin Proc 64: 1361-1372
12. 12. Kadowaki H, Tobe K, Mori Y et al. (1993) Mitochondrial gene mutation and insulin-deficient type of diabetes mellitus. Lancet 341: 893-894
13. 13. Awata T, Matsumoto T, Iwamoto MA et al. (1993) Japanese case of diabetes mellitus and deafness with mutation in mitochondrial tRNA (leu(UUR)) gene. Lancet 341: 1291-1292
14. 14. Hirai M, Suzuki S, Onoda M et al. (1996) Mitochondrial DNA 3394 mutation in the NADH dehydrogenase subunit 1 associated with non-insulin-dependent diabetes mellitus. Biochem Biophys Res Comm 219: 951-955
15. 15. Gerbitz KD, Gempel K, Brdiczka D (1996) Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit. Diabetes 45: 113-116
16. 16. Velho G, Byrne MM, Clement K et al. (1996) Clinical phenotypes, insulin secretion and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNA (Leu(UUR)) gene mutation. Diabetes 45: 478-487
17. 17. Gebhart SS, Shoffner JM, Koontz D et al. (1996) Insulin resistance associated with maternally inherited diabetes and deafness. Metabolism 45: 526-531
18. 18. Oka Y, Katagiri H, Ishihara T et al. (1996) Beta-cell loss and glucose induced signalling defects in diabetes mellitus caused by mitochondrial tRNA (Leu(UUR)) gene mutation. Diabet Med 13:S98-S102
19. Leu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat Genet 1: 368-371
20. 20. Malaisse WJ (1992) Glucose sensing by the pancreatic β-cell: the mitochondrial part. Int J Biochem Cell Biol 24: 693-701
21. 21. Nichols CG, Shyng SL, Nestorowicz A et al. (1996) Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272: 1785-1787
22. 22. Matschinsky FM (1996) A lesson in metabolic regulation inspired by the glucokinase sensor paradigm. Diabetes 45: 223-241
23. 23. Berdanier CD, Kras K, Wickwire K et al. (1997) Progressive glucose intolerance and renal disease in aging rats. Int J Diabetes 5: 27-38
24. 24. Berdanier CD, Kras K, Wickwire K et al. (1998) Whole egg delays the age related impaired glucose tolerance of BHE/ Cdb rats. Proc Soc Exp Biol Med 219: 28-36
25. 25. Berdanier CD, Johnson B, Hartle DK et al. (1992) Lifespan is shortened in BHE/Cdb rats fed a diet containing 9% menhaden oil and 1% corn oil. J Nutr 122: 1309-1317