The sigma-1 receptor antagonist PB212 reduces the Ca 2+-release through the inositol (1, 4, 5)-trisphosphate receptor in SK-N-SH cells

European Journal of Pharmacology

Volumn 684, Issue 1-3, 2012, Pages 59-63

  Gasparre, Giuseppe ^a   Abate, Carmen ^a   Berardi, Francesco ^a   Cassano, Giuseppe ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Endoplasmic reticulum; Mitochondria; Neuromodulation; Receptor; Tumor

Indexed keywords

4 METHYL 1 [4 (6 METHOXYNAPHTHALEN 1 YL)BUTYL]PIPERIDINE; BRADYKININ; CALCIUM ION; CARBACHOL; FURA 2; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; OPIATE AGONIST; OPIATE ANTAGONIST; PHOSPHOLIPASE C; RADIOLIGAND; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING COMPETITION; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL MEMBRANE TRANSPORT; CELL STRAIN; CELL STRAIN LOVO; CELL STRAIN MCF 7; CELL STRAIN SK N SH CELL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

CALCIUM; CALCIUM SIGNALING; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; HOMEOSTASIS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INTRACELLULAR SPACE; LIGANDS; NAPHTHALENES; PIPERIDINES; RECEPTORS, SIGMA; SUBSTRATE SPECIFICITY;

EID: 84860840512     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.03.021     Document Type: Article

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