-
1
-
-
61849170035
-
TLRs and innate immunity
-
Beutler BA. (2009) TLRs and innate immunity. Blood. 113:1399-407.
-
(2009)
Blood
, vol.113
, pp. 1399-1407
-
-
Beutler, B.A.1
-
3
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
Liew FY, Xu D, Brint EK, O'Neill LA. (2005) Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 5:446-58.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
4
-
-
44649132540
-
Host innate immune receptors and beyond: Making sense of microbial infections
-
Ishii KJ, Koyama S, Nakagawa A, Coban C, Akira S (2008) Host innate immune receptors and beyond: making sense of microbial infections. Cell Host Microbe. 3:352-63.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 352-363
-
-
Ishii, K.J.1
Koyama, S.2
Nakagawa, A.3
Coban, C.4
Akira, S.5
-
5
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27:519-50.
-
(2009)
Annu. Rev. Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
6
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, et al. (2002) IRAK-M is a negative regulator of Toll-like receptor signaling. Cell. 110:191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
-
7
-
-
38449086201
-
Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model
-
van't Veer C, et al. (2007) Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model. J. Immunol. 179:7110-20.
-
(2007)
J. Immunol
, vol.179
, pp. 7110-7120
-
-
van't Veer, C.1
-
8
-
-
67650401419
-
Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)
-
Wiersinga WJ, et al. (2009) Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis). Crit. Care Med. 37:569-76.
-
(2009)
Crit. Care Med
, vol.37
, pp. 569-576
-
-
Wiersinga, W.J.1
-
9
-
-
33748317968
-
Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M
-
Deng JC, et al. (2006) Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J. Clin. Invest. 116:2532-42.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2532-2542
-
-
Deng, J.C.1
-
11
-
-
34250805968
-
IRAK-M is involved in the pathogenesis of early-onset persistent asthma
-
Balaci L, et al. (2007) IRAK-M is involved in the pathogenesis of early-onset persistent asthma. Am. J. Hum. Genet. 80:1103-14.
-
(2007)
Am. J. Hum. Genet
, vol.80
, pp. 1103-1114
-
-
Balaci, L.1
-
12
-
-
68149169644
-
TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia
-
Lagler H, et al. (2009) TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J. Immunol. 183:2027-36.
-
(2009)
J. Immunol
, vol.183
, pp. 2027-2036
-
-
Lagler, H.1
-
13
-
-
1442308091
-
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide
-
Rijneveld AW, et al. (2004) Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide. Blood. 103:1702-9.
-
(2004)
Blood
, vol.103
, pp. 1702-1709
-
-
Rijneveld, A.W.1
-
14
-
-
33846922738
-
Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia
-
Renckens R, et al. (2007) Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia. Blood. 109:1593-601.
-
(2007)
Blood
, vol.109
, pp. 1593-1601
-
-
Renckens, R.1
-
15
-
-
1342324587
-
Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
-
Knapp S, et al. (2004) Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J. Immunol. 172:3132-8.
-
(2004)
J. Immunol
, vol.172
, pp. 3132-3138
-
-
Knapp, S.1
-
16
-
-
34547607225
-
Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
-
Wiersinga WJ, et al. (2007) Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis). PLoS Med. 4:e248.
-
(2007)
PLoS Med
, vol.4
-
-
Wiersinga, W.J.1
-
17
-
-
55849089083
-
MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei
-
Wiersinga WJ, Wieland CW, Roelofs JJ, van der Poll T. (2008) MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei. PLoS One. 3:e3494.
-
(2008)
PLoS One
, vol.3
-
-
Wiersinga, W.J.1
Wieland, C.W.2
Roelofs, J.J.3
van der Poll, T.4
-
18
-
-
73449119607
-
CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages
-
van der Windt GJ, van't Veer C, Florquin S, van der Poll T. (2010) CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages. Infect. Immun. 78:115-24.
-
(2010)
Infect. Immun
, vol.78
, pp. 115-124
-
-
van der Windt, G.J.1
van't Veer, C.2
Florquin, S.3
van der Poll, T.4
-
19
-
-
79957443462
-
Osteopontin impairs host defense during pneumococcal pneumonia
-
van der Windt GJ, et al. (2011) Osteopontin impairs host defense during pneumococcal pneumonia. J. Infect. Dis. 203:1850-8.
-
(2011)
J. Infect. Dis
, vol.203
, pp. 1850-1858
-
-
van der Windt, G.J.1
-
21
-
-
39049085847
-
Acute lower respiratory tract infection
-
Mizgerd JP. (2008) Acute lower respiratory tract infection. N. Engl. J. Med. 358:716-27.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 716-727
-
-
Mizgerd, J.P.1
-
22
-
-
0032169656
-
Lung-specific transgenic expression of KC enhances resistance to Klebsiella pneumoniae in mice
-
Tsai WC, et al. (1998) Lung-specific transgenic expression of KC enhances resistance to Klebsiella pneumoniae in mice. J. Immunol. 161:2435-40.
-
(1998)
J. Immunol
, vol.161
, pp. 2435-2440
-
-
Tsai, W.C.1
-
23
-
-
17944364849
-
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
-
Ye P, et al. (2001) Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J. Exp. Med. 194:519-27.
-
(2001)
J. Exp. Med
, vol.194
, pp. 519-527
-
-
Ye, P.1
-
25
-
-
65249089826
-
Lipocalin 2 is required for pulmonary host defense against Klebsiella infection
-
Chan YR, et al. (2009) Lipocalin 2 is required for pulmonary host defense against Klebsiella infection. J. Immunol. 182:4947-56.
-
(2009)
J. Immunol
, vol.182
, pp. 4947-4956
-
-
Chan, Y.R.1
-
26
-
-
20044369387
-
Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium
-
Jeyaseelan S, et al. (2005) Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium. Am. J. Respir. Cell Mol. Biol. 32:531-9.
-
(2005)
Am. J. Respir. Cell Mol. Biol
, vol.32
, pp. 531-539
-
-
Jeyaseelan, S.1
-
27
-
-
66349106491
-
Myeloid differentiation protein-2-dependent and-independent neutrophil accumulation during Escherichia coli pneumonia
-
Cai S, Zemans RL, Young SK, Worthen GS, Jeyaseelan S. (2009) Myeloid differentiation protein-2-dependent and-independent neutrophil accumulation during Escherichia coli pneumonia. Am. J. Respir. Cell Mol. Biol. 40:701-9.
-
(2009)
Am. J. Respir. Cell Mol. Biol
, vol.40
, pp. 701-709
-
-
Cai, S.1
Zemans, R.L.2
Young, S.K.3
Worthen, G.S.4
Jeyaseelan, S.5
-
28
-
-
40049098958
-
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
Aujla SJ, et al. (2008) IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14:275-81.
-
(2008)
Nat. Med
, vol.14
, pp. 275-281
-
-
Aujla, S.J.1
-
29
-
-
0033528072
-
Trends in infectious disease mortality in the United States during the 20th century
-
Armstrong GL, Conn LA, Pinner RW. (1999) Trends in infectious disease mortality in the United States during the 20th century. JAMA. 281:61-6.
-
(1999)
JAMA
, vol.281
, pp. 61-66
-
-
Armstrong, G.L.1
Conn, L.A.2
Pinner, R.W.3
-
30
-
-
77953316015
-
Both TRIF-and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection
-
Cai S, Batra S, Shen L, Wakamatsu N, Jeyaseelan S. (2009) Both TRIF-and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection. J. Immunol. 183:6629-38.
-
(2009)
J. Immunol
, vol.183
, pp. 6629-6638
-
-
Cai, S.1
Batra, S.2
Shen, L.3
Wakamatsu, N.4
Jeyaseelan, S.5
-
31
-
-
0032734726
-
Clinical aspects: From systemic inflammation to 'immu-noparalysis'
-
Volk HD, Reinke P, Docke WD. (2000) Clinical aspects: from systemic inflammation to 'immu-noparalysis'. Chem. Immunol. 74:162-77.
-
(2000)
Chem. Immunol
, vol.74
, pp. 162-177
-
-
Volk, H.D.1
Reinke, P.2
Docke, W.D.3
-
32
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE. (2003) The pathophysiology and treatment of sepsis. N. Engl. J. Med. 348:138-50.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
33
-
-
53249098838
-
Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells
-
Liu ZJ, et al. (2008) Up-regulation of IRAK-M is essential for endotoxin tolerance induced by a low dose of lipopolysaccharide in Kupffer cells. J. Surg. Res. 150:34-9.
-
(2008)
J. Surg. Res
, vol.150
, pp. 34-39
-
-
Liu, Z.J.1
-
34
-
-
0842305634
-
Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice
-
Branger J, et al. (2004) Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice. Infect. Immun. 72:788-94.
-
(2004)
Infect. Immun
, vol.72
, pp. 788-794
-
-
Branger, J.1
-
35
-
-
11144292663
-
Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria
-
Schurr JR, et al. (2005) Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria. Infect. Immun. 73:532-45.
-
(2005)
Infect. Immun
, vol.73
, pp. 532-545
-
-
Schurr, J.R.1
-
36
-
-
35748965880
-
TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: Role of dendritic cells
-
Bhan U, et al. (2007) TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells. J. Immunol. 179:3937-46.
-
(2007)
J. Immunol
, vol.179
, pp. 3937-3946
-
-
Bhan, U.1
-
37
-
-
12744262857
-
Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae
-
Tanabe M, et al. (2005) Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoniae. J. Med. Microbiol. 54:7-13.
-
(2005)
J. Med. Microbiol
, vol.54
, pp. 7-13
-
-
Tanabe, M.1
-
38
-
-
77949313888
-
Critical role of IL-1 receptorassociated kinase-M in regulating chemokinedependent deleterious inflammation in murine influenza pneumonia
-
Seki M, et al. (2010) Critical role of IL-1 receptorassociated kinase-M in regulating chemokinedependent deleterious inflammation in murine influenza pneumonia. J. Immunol. 184:1410-8.
-
(2010)
J. Immunol
, vol.184
, pp. 1410-1418
-
-
Seki, M.1
-
39
-
-
33745684282
-
Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virusinduced acute pneumonia
-
Le Goffic R, et al. (2006) Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virusinduced acute pneumonia. PLoS Pathog. 2:e53.
-
(2006)
PLoS Pathog
, vol.2
-
-
Le Goffic, R.1
-
40
-
-
64649097032
-
Innate immunity and inflammation-two facets of the same anti-infectious reaction
-
Si-Tahar M, Touqui L, Chignard M. (2009) Innate immunity and inflammation-two facets of the same anti-infectious reaction. Clin. Exp. Immunol. 156:194-8.
-
(2009)
Clin. Exp. Immunol
, vol.156
, pp. 194-198
-
-
Si-Tahar, M.1
Touqui, L.2
Chignard, M.3
-
41
-
-
77956939946
-
Influenza virus-cytokineprotease cycle in the pathogenesis of vascular hyperpermeability in severe influenza
-
Wang S, et al. (2010) Influenza virus-cytokineprotease cycle in the pathogenesis of vascular hyperpermeability in severe influenza. J. Infect. Dis. 202:991-1001.
-
(2010)
J. Infect. Dis
, vol.202
, pp. 991-1001
-
-
Wang, S.1
-
42
-
-
80052940381
-
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection
-
Teijaro JR, et al. (2011. Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Cell. 146:980-91.
-
(2011)
Cell
, vol.146
, pp. 980-991
-
-
Teijaro, J.R.1
|