Cardiotoxicity of acetogenins from Persea americana occurs through the mitochondrial permeability transition pore and caspase-dependent apoptosis pathways

Journal of Bioenergetics and Biomembranes

Volumn 44, Issue 4, 2012, Pages 461-471

  Silva Platas, Christian ^a,b   García, Noemí ^a,b   Fernández Sada, Evaristo ^a   Dávila, Daniel ^a   Hernández Brenes, Carmen ^b   Rodríguez, Dariana ^a,b   García Rivas, Gerardo ^a,b  

^a ESCUELA DE MEDICINA Y CIENCIAS DE LA SALUD   (Mexico)

^b SCHOOL OF ENGINEERING AND SCIENCES   (Mexico)

Author keywords

Acetogenins; Avocado; Mitochondria; Permeability transition; Toxicity

Indexed keywords

ACETOGENIN; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CYCLOSPORIN A; HERBACEOUS AGENT; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AVOCADO; CARDIOTOXICITY; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PHOSPHATE TRANSPORT; PLANT SEED;

ACETOGENINS; ANIMALS; APOPTOSIS; CARDIOTOXINS; ELECTRON TRANSPORT COMPLEX I; HUMANS; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXYGEN CONSUMPTION; PERSEA; RATS; RATS, WISTAR; SEEDS;

ANNONACEAE; LAURACEAE; PERSEA AMERICANA;

EID: 84866737587     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-012-9452-1     Document Type: Article

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