메뉴 건너뛰기




Volumn 53, Issue 1-3, 2012, Pages 200-212

Immune modulation of inflammatory conditions: Regulatory T cells for treatment of GvHD

Author keywords

Adoptive cell therapy; CD39; CD49d; Cell isolation; Clinical trial; Rapamycin; Treg; TREM

Indexed keywords

ALPHA4 INTEGRIN; CD39 ANTIGEN; CHEMOKINE RECEPTOR CCR6; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 7 RECEPTOR;

EID: 84866736535     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-012-8267-9     Document Type: Article
Times cited : (20)

References (113)
  • 2
    • 79956121863 scopus 로고    scopus 로고
    • Mouse models of graft-versus-host disease: Advances and limitations
    • Schroeder MA, DiPersio JF. Mouse models of graft-versus-host disease: advances and limitations. Dis Model Mech. 2011;4(3):318-33.
    • (2011) Dis Model Mech. , vol.4 , Issue.3 , pp. 318-333
    • Schroeder, M.A.1    Dipersio, J.F.2
  • 4
    • 33845457221 scopus 로고    scopus 로고
    • The changing face of graft-versus-host disease
    • Schaffer JV. The changing face of graft-versus-host disease. Semin Cutan Med Surg. 2006;25(4):190-200.
    • (2006) Semin Cutan Med Surg. , vol.25 , Issue.4 , pp. 190-200
    • Schaffer, J.V.1
  • 5
    • 34948865802 scopus 로고    scopus 로고
    • High-risk HLA allele mismatch combinations responsible for severe acute graft-versus- host disease and implication for its molecular mechanism
    • Kawase T, Morishima Y, Matsuo K, Kashiwase K, Inoko H, Saji H, Kato S, Juji T, Kodera Y, Sasazuki T. High-risk HLA allele mismatch combinations responsible for severe acute graft-versus- host disease and implication for its molecular mechanism. Blood. 2007;110(7):2235-41.
    • (2007) Blood. , vol.110 , Issue.7 , pp. 2235-2241
    • Kawase, T.1    Morishima, Y.2    Matsuo, K.3    Kashiwase, K.4    Inoko, H.5    Saji, H.6    Kato, S.7    Juji, T.8    Kodera, Y.9    Sasazuki, T.10
  • 8
    • 47249151462 scopus 로고    scopus 로고
    • Sirolimus, tacrolimus, and low-dose methotrexate as graft-versushost disease prophylaxis in related and unrelated donor reducedintensity conditioning allogeneic peripheral blood stem cell transplantation
    • Alyea EP, Li S, Kim HT, Cutler C, Ho V, Soiffer RJ, Antin JH. Sirolimus, tacrolimus, and low-dose methotrexate as graft-versushost disease prophylaxis in related and unrelated donor reducedintensity conditioning allogeneic peripheral blood stem cell transplantation. Biol Blood Marrow Transpl. 2008;14(8):920-6.
    • (2008) Biol Blood Marrow Transpl. , vol.14 , Issue.8 , pp. 920-926
    • Alyea, E.P.1    Li, S.2    Kim, H.T.3    Cutler, C.4    Ho, V.5    Soiffer, R.J.6    Antin, J.H.7
  • 9
    • 67349198571 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: An observational cohort study
    • Schleuning M, Judith D, Jedlickova Z, Stubig T, Heshmat M, Baurmann H, Schwerdtfeger R. Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study. Bone Marrow Transpl. 2009;43(9):717-23.
    • (2009) Bone Marrow Transpl. , vol.43 , Issue.9 , pp. 717-723
    • Schleuning, M.1    Judith, D.2    Jedlickova, Z.3    Stubig, T.4    Heshmat, M.5    Baurmann, H.6    Schwerdtfeger, R.7
  • 10
    • 0027323876 scopus 로고
    • Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: Roles of calcineurin binding and cellular location
    • Bram RJ, Hung DT, Martin PK, Schreiber SL, Crabtree GR. Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. Mol Cell Biol. 1993;13(8):4760-9.
    • (1993) Mol Cell Biol. , vol.13 , Issue.8 , pp. 4760-4769
    • Bram, R.J.1    Hung, D.T.2    Martin, P.K.3    Schreiber, S.L.4    Crabtree, G.R.5
  • 11
    • 0025017879 scopus 로고
    • FK-506 enters the clinic
    • Thomson AW. FK-506 enters the clinic. Immunol Today. 1990;11(2):35-6.
    • (1990) Immunol Today. , vol.11 , Issue.2 , pp. 35-36
    • Thomson, A.W.1
  • 14
    • 77958553914 scopus 로고    scopus 로고
    • Sirolimus immunosuppression for graftversus- host disease prophylaxis and therapy: An update
    • Cutler C, Antin JH. Sirolimus immunosuppression for graftversus- host disease prophylaxis and therapy: an update. Curr Opin Hematol. 2010;17(6):500-4.
    • (2010) Curr Opin Hematol. , vol.17 , Issue.6 , pp. 500-504
    • Cutler, C.1    Antin, J.H.2
  • 15
    • 33845379986 scopus 로고    scopus 로고
    • Rapamycin promotes expansion of functional CD4?CD25?FOXP3? regulatory T cells of both healthy subjects and type 1 diabetic patients
    • Battaglia M, Stabilini A, Migliavacca B, Horejs-Hoeck J, Kaupper T, Roncarolo MG. Rapamycin promotes expansion of functional CD4?CD25?FOXP3? regulatory T cells of both healthy subjects and type 1 diabetic patients. J Immunol. 2006;177(12):8338-47.
    • (2006) J Immunol. , vol.177 , Issue.12 , pp. 8338-8347
    • Battaglia, M.1    Stabilini, A.2    Migliavacca, B.3    Horejs-Hoeck, J.4    Kaupper, T.5    Roncarolo, M.G.6
  • 16
    • 33749259809 scopus 로고    scopus 로고
    • A novel mechanism of action for anti-thymocyte globulin: Induction of CD4?CD25?Foxp3? regulatory T cells
    • Lopez M, Clarkson MR, Albin M, Sayegh MH, Najafian N. A novel mechanism of action for anti-thymocyte globulin: induction of CD4?CD25?Foxp3? regulatory T cells. J Am Soc Nephrol. 2006;17(10):2844-53.
    • (2006) J Am Soc Nephrol. , vol.17 , Issue.10 , pp. 2844-2853
    • Lopez, M.1    Clarkson, M.R.2    Albin, M.3    Sayegh, M.H.4    Najafian, N.5
  • 18
    • 27744586984 scopus 로고    scopus 로고
    • OKT3 muromonab as second-line and subsequent treatment in recipients of stem cell allografts with steroid-resistant acute graft-versus-host disease
    • Knop S, Hebart H, Gscheidle H, Holler E, Kolb HJ, Niederwieser D, Einsele H. OKT3 muromonab as second-line and subsequent treatment in recipients of stem cell allografts with steroid-resistant acute graft-versus-host disease. Bone Marrow Transpl. 2005;36(9):831-7.
    • (2005) Bone Marrow Transpl. , vol.36 , Issue.9 , pp. 831-837
    • Knop, S.1    Hebart, H.2    Gscheidle, H.3    Holler, E.4    Kolb, H.J.5    Niederwieser, D.6    Einsele, H.7
  • 20
    • 0021194133 scopus 로고
    • Fatal Epstein-Barr-virus-associated proliferation of donor B cells after treatment of acute graft-versushost disease with a murine anti-T-cell antibody
    • Martin PJ, Shulman HM, Schubach WH, Hansen JA, Fefer A, Miller G, Thomas ED. Fatal Epstein-Barr-virus-associated proliferation of donor B cells after treatment of acute graft-versushost disease with a murine anti-T-cell antibody. Ann Intern Med. 1984;101(3):310-5.
    • (1984) Ann Intern Med. , vol.101 , Issue.3 , pp. 310-315
    • Martin, P.J.1    Shulman, H.M.2    Schubach, W.H.3    Hansen, J.A.4    Fefer, A.5    Miller, G.6    Thomas, E.D.7
  • 25
    • 0036947659 scopus 로고    scopus 로고
    • Basiliximab is well tolerated and effective in the treatment of steroid-refractory acute graft-versus-host disease after allogeneic stem cell transplantation
    • Massenkeil G, Rackwitz S, Genvresse I, Rosen O, Dorken B, Arnold R. Basiliximab is well tolerated and effective in the treatment of steroid-refractory acute graft-versus-host disease after allogeneic stem cell transplantation. Bone Marrow Transpl. 2002;30(12):899-903.
    • (2002) Bone Marrow Transpl. , vol.30 , Issue.12 , pp. 899-903
    • Massenkeil, G.1    Rackwitz, S.2    Genvresse, I.3    Rosen, O.4    Dorken, B.5    Arnold, R.6
  • 26
    • 24944433163 scopus 로고    scopus 로고
    • Efficacy of the interleukin-2 receptor antagonist basiliximab in steroid-refractory acute graft-versushost disease
    • Schmidt-Hieber M, Fietz T, Knauf W, Uharek L, Hopfenmuller W, Thiel E, Blau IW. Efficacy of the interleukin-2 receptor antagonist basiliximab in steroid-refractory acute graft-versushost disease. Br J Haematol. 2005;130(4):568-74.
    • (2005) Br J Haematol. , vol.130 , Issue.4 , pp. 568-574
    • Schmidt-Hieber, M.1    Fietz, T.2    Knauf, W.3    Uharek, L.4    Hopfenmuller, W.5    Thiel, E.6    Blau, I.W.7
  • 32
    • 34047171006 scopus 로고    scopus 로고
    • Why hasn't eliminating acute rejection improved graft survival?
    • Tantravahi J, Womer KL, Kaplan B. Why hasn't eliminating acute rejection improved graft survival? Annu Rev Med. 2007;58:369-85.
    • (2007) Annu Rev Med. , vol.58 , pp. 369-385
    • Tantravahi, J.1    Womer, K.L.2    Kaplan, B.3
  • 33
    • 78649876277 scopus 로고    scopus 로고
    • The immunosuppressive pipeline: Meeting unmet needs in liver transplantation
    • Selzner N, Grant DR, Shalev I, Levy GA. The immunosuppressive pipeline: meeting unmet needs in liver transplantation. Liver Transpl. 2010;16(12):1359-72.
    • (2010) Liver Transpl. , vol.16 , Issue.12 , pp. 1359-1372
    • Selzner, N.1    Grant, D.R.2    Shalev, I.3    Levy, G.A.4
  • 35
    • 79952476648 scopus 로고    scopus 로고
    • Mesenchymal stromal cells for graft-versus-host disease: Basic aspects and clinical outcomes
    • Sato K, Ozaki K, Mori M, Muroi K, Ozawa K. Mesenchymal stromal cells for graft-versus-host disease : basic aspects and clinical outcomes. J Clin Exp Hematop. 2010;50(2):79-89.
    • (2010) J Clin Exp Hematop. , vol.50 , Issue.2 , pp. 79-89
    • Sato, K.1    Ozaki, K.2    Mori, M.3    Muroi, K.4    Ozawa, K.5
  • 38
    • 70449368623 scopus 로고    scopus 로고
    • Genzyme backs Osiris, despite Prochymal flop
    • Allison M. Genzyme backs Osiris, despite Prochymal flop. Nat Biotechnol. 2009;27(11):966-7.
    • (2009) Nat Biotechnol. , vol.27 , Issue.11 , pp. 966-967
    • Allison, M.1
  • 39
    • 81155124466 scopus 로고    scopus 로고
    • Natural killer cell engineering for cellular therapy of cancer
    • Shook DR, Campana D. Natural killer cell engineering for cellular therapy of cancer. Tissue Antigens. 2011;78(6):409-15.
    • (2011) Tissue Antigens. , vol.78 , Issue.6 , pp. 409-415
    • Shook, D.R.1    Campana, D.2
  • 42
    • 84861186968 scopus 로고    scopus 로고
    • Amelioration of acute graft-versus-host disease by adoptive transfer of ex vivo expanded human cord blood CD4?CD25? forkhead box protein 3? regulatory T cells is associated with the polarization of Treg/Th17 balance in a mouse model
    • doi:10.1111/j.1537-2995.2011.03448.x
    • Yang J, FanH,Hao J, RenY,ChenL, LiG,Xie R, Yang Y, Qian K, LiuM. Amelioration of acute graft-versus-host disease by adoptive transfer of ex vivo expanded human cord blood CD4?CD25? forkhead box protein 3? regulatory T cells is associated with the polarization of Treg/Th17 balance in a mouse model. Transfusion. 2011. doi:10.1111/j.1537-2995.2011.03448.x.
    • (2011) Transfusion.
    • Yang, J.1    Fanhhao, J.2    Renychenl3    Ligxie, R.4    Yang, Y.5    Qian, K.6    Liu, M.7
  • 43
    • 77953644448 scopus 로고    scopus 로고
    • NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects
    • Olson JA, Leveson-Gower DB, Gill S, Baker J, Beilhack A, Negrin RS. NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects. Blood. 2010;115(21):4293-301.
    • (2010) Blood. , vol.11 , Issue.21 , pp. 4293-4301
    • Olson, J.A.1    Leveson-Gower, D.B.2    Gill, S.3    Baker, J.4    Beilhack, A.5    Negrin, R.S.6
  • 44
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299(5609):1057-61.
    • (2003) Science. , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 45
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4?CD25? regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4?CD25? regulatory T cells. Nat Immunol. 2003;4(4):330-6.
    • (2003) Nat Immunol. , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 46
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4?CD25? immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM. Suppressor effector function of CD4?CD25? immunoregulatory T cells is antigen nonspecific. J Immunol. 2000;164(1):183-90.
    • (2000) J Immunol. , vol.164 , Issue.1 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 48
    • 25444497719 scopus 로고    scopus 로고
    • Cutting edge: Direct suppression of B cells by CD4?CD25? regulatory T cells
    • Lim HW, Hillsamer P, Banham AH, Kim CH. Cutting edge: direct suppression of B cells by CD4?CD25? regulatory T cells. J Immunol. 2005;175(7):4180-3.
    • (2005) J Immunol. , vol.175 , Issue.7 , pp. 4180-4183
    • Lim, H.W.1    Hillsamer, P.2    Banham, A.H.3    Kim, C.H.4
  • 49
    • 15944425718 scopus 로고    scopus 로고
    • CCR6 expression defines regulatory effector/ memory-like cells within the CD25(?)CD4? T-cell subset
    • Kleinewietfeld M, Puentes F, Borsellino G, Battistini L, Rotzschke O, Falk K. CCR6 expression defines regulatory effector/ memory-like cells within the CD25(?)CD4? T-cell subset. Blood. 2005;105(7):2877-86.
    • (2005) Blood. , vol.105 , Issue.7 , pp. 2877-2886
    • Kleinewietfeld, M.1    Puentes, F.2    Borsellino, G.3    Battistini, L.4    Rotzschke, O.5    Falk, K.6
  • 50
    • 0348013075 scopus 로고    scopus 로고
    • Human CD4?CD25? regulatory cells have marked and sustained effects on CD8 ? T cell activation
    • Camara NO, Sebille F, Lechler RI. Human CD4?CD25? regulatory cells have marked and sustained effects on CD8 ? T cell activation. Eur J Immunol. 2003;33(12):3473-83.
    • (2003) Eur J Immunol. , vol.33 , Issue.12 , pp. 3473-3483
    • Camara, N.O.1    Sebille, F.2    Lechler, R.I.3
  • 52
    • 79952201053 scopus 로고    scopus 로고
    • Natural and induced T CD4?CD25?FOXP3? regulatory T cells
    • Chatenoud L. Natural and induced T CD4?CD25?FOXP3? regulatory T cells. Methods Mol Biol. 2011;677:3-13.
    • (2011) Methods Mol Biol. , vol.677 , pp. 3-13
    • Chatenoud, L.1
  • 53
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155(3):1151-64.
    • (1995) J Immunol. , vol.155 , Issue.3 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 56
    • 58849118836 scopus 로고    scopus 로고
    • Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
    • Huehn J, Polansky JK, Hamann A. Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol. 2009;9(2):83-9.
    • (2009) Nat Rev Immunol. , vol.9 , Issue.2 , pp. 83-89
    • Huehn, J.1    Polansky, J.K.2    Hamann, A.3
  • 57
    • 65549115862 scopus 로고    scopus 로고
    • Plasticity of CD4? T cell lineage differentiation
    • Zhou L, Chong MM, Littman DR. Plasticity of CD4? T cell lineage differentiation. Immunity. 2009;30(5):646-55.
    • (2009) Immunity. , vol.30 , Issue.5 , pp. 646-655
    • Zhou, L.1    Chong, M.M.2    Littman, D.R.3
  • 58
    • 0032536869 scopus 로고    scopus 로고
    • Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
    • Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med. 1998;187(6):875-83.
    • (1998) J Exp Med. , vol.187 , Issue.6 , pp. 875-883
    • Sallusto, F.1    Lenig, D.2    MacKay, C.R.3    Lanzavecchia, A.4
  • 60
    • 0035903307 scopus 로고    scopus 로고
    • Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(?)CD25(?) regulatory T cells
    • Iellem A, Mariani M, Lang R, Recalde H, Panina-Bordignon P, Sinigaglia F, D'Ambrosio D. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(?)CD25(?) regulatory T cells. J Exp Med. 2001;194(6):847-53.
    • (2001) J Exp Med. , vol.194 , Issue.6 , pp. 847-853
    • Iellem, A.1    Mariani, M.2    Lang, R.3    Recalde, H.4    Panina-Bordignon, P.5    Sinigaglia, F.6    D'ambrosio, D.7
  • 62
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra A, Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med. 2004;10(8):801-5.
    • (2004) Nat Med. , vol.10 , Issue.8 , pp. 801-805
    • O'garra, A.1    Vieira, P.2
  • 64
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(?)CD25(?) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4(?)CD25(?) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med. 2001;194(5):629-44.
    • (2001) J Exp Med. , vol.194 , Issue.5 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 65
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3? regulatory T cell: A jack of all trades, master of regulation
    • Tang Q, Bluestone JA. The Foxp3? regulatory T cell: a jack of all trades, master of regulation. Nat Immunol. 2008;9(3): 239-44.
    • (2008) Nat Immunol. , vol.9 , Issue.3 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 66
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science. 2002;296(5566):301-5.
    • (2002) Science. , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 67
    • 0142184953 scopus 로고    scopus 로고
    • Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptorindependent mechanisms
    • Beigi RD, Kertesy SB, Aquilina G, Dubyak GR. Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptorindependent mechanisms. Br J Pharmacol. 2003;140(3):507-19.
    • (2003) Br J Pharmacol. , vol.140 , Issue.3 , pp. 507-519
    • Beigi, R.D.1    Kertesy, S.B.2    Aquilina, G.3    Dubyak, G.R.4
  • 68
    • 0035874638 scopus 로고    scopus 로고
    • The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells
    • Wilkin F, Duhant X, Bruyns C, Suarez-Huerta N, Boeynaems JM, Robaye B. The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells. J Immunol. 2001;166(12):7172-7.
    • (2001) J Immunol. , vol.166 , Issue.12 , pp. 7172-7177
    • Wilkin, F.1    Duhant, X.2    Bruyns, C.3    Suarez-Huerta, N.4    Boeynaems, J.M.5    Robaye, B.6
  • 70
    • 0035253431 scopus 로고    scopus 로고
    • Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th1 responses
    • la Sala A, Ferrari D, Corinti S, Cavani A, Di Virgilio F, Girolomoni G. Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th1 responses. J Immunol. 2001;166(3):1611-7.
    • (2001) J Immunol. , vol.166 , Issue.3 , pp. 1611-1617
    • La Sala, A.1    Ferrari, D.2    Corinti, S.3    Cavani, A.4    Di Virgilio, F.5    Girolomoni, G.6
  • 71
    • 77950865221 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation: Does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?
    • Salcido-Ochoa F, Tsang J, Tam P, Falk K, Rotzschke O. Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role? Transpl Rev (Orlando). 2010;24(2):52-66.
    • (2010) Transpl Rev (Orlando). , vol.24 , Issue.2 , pp. 52-66
    • Salcido-Ochoa, F.1    Tsang, J.2    Tam, P.3    Falk, K.4    Rotzschke, O.5
  • 76
    • 23844435586 scopus 로고    scopus 로고
    • High sensitivity of CD4?CD25? regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: A role for P2X7 receptors
    • Aswad F, Kawamura H, Dennert G. High sensitivity of CD4?CD25? regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors. J Immunol. 2005;175(5):3075-83.
    • (2005) J Immunol. , vol.175 , Issue.5 , pp. 3075-3083
    • Aswad, F.1    Kawamura, H.2    Dennert, G.3
  • 77
    • 0031933227 scopus 로고    scopus 로고
    • Ecto-enzyme and signaling functions of lymphocyte CD73
    • Resta R, Yamashita Y, Thompson LF. Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev. 1998;161:95-109.
    • (1998) Immunol Rev. , vol.161 , pp. 95-109
    • Resta, R.1    Yamashita, Y.2    Thompson, L.F.3
  • 79
    • 20444373378 scopus 로고    scopus 로고
    • Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo
    • Erdmann AA, Gao ZG, Jung U, Foley J, Borenstein T, Jacobson KA, Fowler DH. Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo. Blood. 2005;105(12):4707-14.
    • (2005) Blood. , vol.105 , Issue.12 , pp. 4707-4714
    • Erdmann, A.A.1    Gao, Z.G.2    Jung, U.3    Foley, J.4    Borenstein, T.5    Jacobson, K.A.6    Fowler, D.H.7
  • 80
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(?)CD25(?) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type CD4(?)CD25(?) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J Exp Med. 2002;196(3):389-99.
    • (2002) J Exp Med. , vol.196 , Issue.3 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 82
    • 0027764593 scopus 로고
    • Engraftment of human lymphoid cells into newborn SCID mice leads to graft-versus-host disease
    • Pflumio F, Lapidot T, Murdoch B, Patterson B, Dick JE. Engraftment of human lymphoid cells into newborn SCID mice leads to graft-versus-host disease. Int Immunol. 1993;5(12): 1509-22.
    • (1993) Int Immunol. , vol.5 , Issue.12 , pp. 1509-1522
    • Pflumio, F.1    Lapidot, T.2    Murdoch, B.3    Patterson, B.4    Dick, J.E.5
  • 84
    • 0032227930 scopus 로고    scopus 로고
    • T lymphocytes determine the development of xeno GVHD and of human hemopoiesis in NOD/SCID mice following human umbilical cord blood transplantation
    • Verlinden SF, Mulder AH, de Leeuw JP, van Bekkum DW. T lymphocytes determine the development of xeno GVHD and of human hemopoiesis in NOD/SCID mice following human umbilical cord blood transplantation. Stem Cells. 1998;16(Suppl 1):205-17.
    • (1998) Stem Cells. , vol.16 , Issue.SUPPL. 1 , pp. 205-217
    • Verlinden, S.F.1    Mulder, A.H.2    De Leeuw, J.P.3    Van Bekkum, D.W.4
  • 85
    • 65549127618 scopus 로고    scopus 로고
    • Human T regulatory cell therapy: Take a billion or so and call me in the morning
    • Riley JL, June CH, Blazar BR. Human T regulatory cell therapy: take a billion or so and call me in the morning. Immunity. 2009;30(5):656-65.
    • (2009) Immunity. , vol.30 , Issue.5 , pp. 656-665
    • Riley, J.L.1    June, C.H.2    Blazar, B.R.3
  • 86
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(?)CD25(?) immune regulatory cells inhibits graft-versus-host disease lethality
    • Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded CD4(?)CD25(?) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 2002;99(10): 3493-9.
    • (2002) Blood. , vol.99 , Issue.10 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 87
    • 2542496868 scopus 로고    scopus 로고
    • Induction of antigen-specific tolerance to bone marrow allografts with CD4?CD25? T lymphocytes
    • Joffre O, Gorsse N, Romagnoli P, Hudrisier D, van Meerwijk JP. Induction of antigen-specific tolerance to bone marrow allografts with CD4?CD25? T lymphocytes. Blood. 2004;103(11):4216-21.
    • (2004) Blood. , vol.103 , Issue.11 , pp. 4216-4221
    • Joffre, O.1    Gorsse, N.2    Romagnoli, P.3    Hudrisier, D.4    Van Meerwijk, J.P.5
  • 92
    • 79551678785 scopus 로고    scopus 로고
    • Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice
    • Semple K, Yu Y, Wang D, Anasetti C, Yu XZ. Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice. Biol Blood Marrow Transpl. 2011;17(3):309-18.
    • (2011) Biol Blood Marrow Transpl. , vol.17 , Issue.3 , pp. 309-318
    • Semple, K.1    Yu, Y.2    Wang, D.3    Anasetti, C.4    Yu, X.Z.5
  • 93
    • 33644898608 scopus 로고    scopus 로고
    • Graft-versus-leukemia and graftversus- host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras
    • Xia G, Truitt RL, Johnson BD. Graft-versus-leukemia and graftversus- host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras. Biol Blood Marrow Transpl. 2006;12(4):397-407.
    • (2006) Biol Blood Marrow Transpl. , vol.12 , Issue.4 , pp. 397-407
    • Xia, G.1    Truitt, R.L.2    Johnson, B.D.3
  • 96
    • 80053597291 scopus 로고    scopus 로고
    • Regulatory T cells in stem cell transplantation: Strategies and first clinical experiences
    • Edinger M, Hoffmann P. Regulatory T cells in stem cell transplantation: strategies and first clinical experiences. Curr Opin Immunol. 2011;23(5):679-84.
    • (2011) Curr Opin Immunol. , vol.23 , Issue.5 , pp. 679-684
    • Edinger, M.1    Hoffmann, P.2
  • 98
    • 3042792942 scopus 로고    scopus 로고
    • CD25?CD4? T cells in human cord blood: An immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene
    • Takahata Y, Nomura A, Takada H, Ohga S, Furuno K, Hikino S, Nakayama H, Sakaguchi S, Hara T. CD25?CD4? T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene. Exp Hematol. 2004;32(7):622-9.
    • (2004) Exp Hematol. , vol.32 , Issue.7 , pp. 622-629
    • Takahata, Y.1    Nomura, A.2    Takada, H.3    Ohga, S.4    Furuno, K.5    Hikino, S.6    Nakayama, H.7    Sakaguchi, S.8    Hara, T.9
  • 99
    • 56049087273 scopus 로고    scopus 로고
    • High purity and yield of natural Tregs from cord blood using a single step selection method
    • Figueroa-Tentori D, Querol S, Dodi IA, Madrigal A, Duggleby R. High purity and yield of natural Tregs from cord blood using a single step selection method. J Immunol Methods. 2008;339(2): 228-35.
    • (2008) J Immunol Methods. , vol.339 , Issue.2 , pp. 228-235
    • Figueroa-Tentori, D.1    Querol, S.2    Dodi, I.A.3    Madrigal, A.4    Duggleby, R.5
  • 100
    • 11244268818 scopus 로고    scopus 로고
    • Cord blood CD4(?)CD25(?)- derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function
    • Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, Porter SB. Cord blood CD4(?)CD25(?)- derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood. 2005;105(2):750-8.
    • (2005) Blood. , vol.105 , Issue.2 , pp. 750-758
    • Godfrey, W.R.1    Spoden, D.J.2    Ge, Y.G.3    Baker, S.R.4    Liu, B.5    Levine, B.L.6    June, C.H.7    Blazar, B.R.8    Porter, S.B.9
  • 104
    • 70249122695 scopus 로고    scopus 로고
    • First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4?CD25?CD127-T regulatory cells
    • Trzonkowski P, Bieniaszewska M, Juscinska J, Dobyszuk A, Krzystyniak A, Marek N, Mysliwska J, Hellmann A. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4?CD25?CD127-T regulatory cells. Clin Immunol. 2009;133(1):22-6.
    • (2009) Clin Immunol. , vol.133 , Issue.1 , pp. 22-26
    • Trzonkowski, P.1    Bieniaszewska, M.2    Juscinska, J.3    Dobyszuk, A.4    Krzystyniak, A.5    Marek, N.6    Mysliwska, J.7    Hellmann, A.8
  • 110
    • 60549115770 scopus 로고    scopus 로고
    • Heterogeneity of natural Foxp3? T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
    • Komatsu N, Mariotti-Ferrandiz ME, Wang Y, Malissen B, Waldmann H, Hori S. Heterogeneity of natural Foxp3? T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci USA. 2009;106(6):1903-8.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.6 , pp. 1903-1908
    • Komatsu, N.1    Mariotti-Ferrandiz, M.E.2    Wang, Y.3    Malissen, B.4    Waldmann, H.5    Hori, S.6
  • 112
    • 67449128008 scopus 로고    scopus 로고
    • Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression
    • Mandapathil M, Lang S, Gorelik E, Whiteside TL. Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression. J Immunol Methods. 2009;346(1-2):55-63.
    • (2009) J Immunol Methods. , vol.346 , Issue.1-2 , pp. 55-63
    • Mandapathil, M.1    Lang, S.2    Gorelik, E.3    Whiteside, T.L.4
  • 113
    • 79958781930 scopus 로고    scopus 로고
    • Separation of human CD4?CD39? T cells by magnetic beads reveals two phenotypically and functionally different subsets
    • Schuler PJ, Harasymczuk M, Schilling B, Lang S, Whiteside TL. Separation of human CD4?CD39? T cells by magnetic beads reveals two phenotypically and functionally different subsets. J Immunol Methods. 2011;369(1-2):59-68.
    • (2011) J Immunol Methods. , vol.36 , Issue.1-2 , pp. 59-68
    • Schuler, P.J.1    Harasymczuk, M.2    Schilling, B.3    Lang, S.4    Whiteside, T.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.