-
1
-
-
20344392658
-
A receptors as a target for the development of novel anxiolytics
-
DOI 10.1517/13543784.14.5.601
-
J.R. Atack The benzodiazepine binding site of GABAA receptors as a target for the development of novel anxiolytics Expert Opinion on Investigational Drugs 14 2005 601 618 (Pubitemid 40790282)
-
(2005)
Expert Opinion on Investigational Drugs
, vol.14
, Issue.5
, pp. 601-618
-
-
Atack, J.R.1
-
2
-
-
79954562339
-
GABAA receptor subtype-selective modulators. I. α2/α3 - Selective agonist as non-sedating anxiolytics
-
J.R. Atack GABAA receptor subtype-selective modulators. I. α2/α3 - selective agonist as non-sedating anxiolytics Current Topics Medicinal Chemistry 11 2011 1176 1202
-
(2011)
Current Topics Medicinal Chemistry
, vol.11
, pp. 1176-1202
-
-
Atack, J.R.1
-
3
-
-
73949094850
-
Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at α1 and α2/3 subtypes
-
N.A. Ator, J.R. Atack, R.J. Hargreaves, D. Burns, and G.R. Dawson Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at α1 and α2/3 subtypes Journal of Pharmacology and Experimental Therapeutics 332 2010 4 16
-
(2010)
Journal of Pharmacology and Experimental Therapeutics
, vol.332
, pp. 4-16
-
-
Ator, N.A.1
Atack, J.R.2
Hargreaves, R.J.3
Burns, D.4
Dawson, G.R.5
-
4
-
-
58049130013
-
GABAA receptors as in vivo substrate fort he anxiolytic action of valerenic acid, a major constituent of valerian root extracts
-
D. Benke, A. Barberis, S. Kopp, K.H. Altmann, M. Schubiger, K.E. Vogt, U. Rudolph, and H. Möhler GABAA receptors as in vivo substrate fort he anxiolytic action of valerenic acid, a major constituent of valerian root extracts Neuropharmacology 56 1 2009 174 181
-
(2009)
Neuropharmacology
, vol.56
, Issue.1
, pp. 174-181
-
-
Benke, D.1
Barberis, A.2
Kopp, S.3
Altmann, K.H.4
Schubiger, M.5
Vogt, K.E.6
Rudolph, U.7
Möhler, H.8
-
5
-
-
34248568013
-
Valerian for Sleep: A Systematic Review and Meta-Analysis
-
DOI 10.1016/j.amjmed.2006.02.026, PII S0002934306002750
-
S. Bent, A. Padula, D. Moore, M. Patterson, and W. Mehling Valerian for sleep: a systematic review and meta-analysis American Journal of Medicine 119 2006 1005 1012 (Pubitemid 44826933)
-
(2006)
American Journal of Medicine
, vol.119
, Issue.12
, pp. 1005-1012
-
-
Bent, S.1
Padula, A.2
Moore, D.3
Patterson, M.4
Mehling, W.5
-
6
-
-
34548407052
-
Scientific evidence for a fixed extract combination (Ze 91019) from Valerian and hops traditionally used as a sleep-inducing aid
-
DOI 10.1007/s10354-007-0442-6
-
A. Brattström Scientific evidence for a fixed extract combination (Ze 91019) from valerian and hops traditionally used as a sleep-inducing aid Wiener Medizinische Wochenschrift 157 2007 367 370 (Pubitemid 47356266)
-
(2007)
Wiener Medizinische Wochenschrift
, vol.157
, Issue.13-14
, pp. 367-370
-
-
Brattstrom, A.1
-
7
-
-
0036705651
-
A receptor mutation β(R192H)
-
DOI 10.1007/s00439-002-0766-7
-
A. Buhr, M.T. Bianchi, R. Baur, P. Courtet, V. Pignay, J.P. Boulenger, S. Gallati, D.J. Hinkle, R.L. Macdonald, and E. Sigel Functional characterization of the new human GABA(A) receptor mutation bet3 (R192H) Human Genetics 111 2002 154 160 (Pubitemid 36075033)
-
(2002)
Human Genetics
, vol.111
, Issue.2
, pp. 154-160
-
-
Buhr, A.1
Bianchi, M.T.2
Baur, R.3
Courtet, P.4
Pignay, V.5
Boulenger, J.P.6
Gallati, S.7
Hinkle, D.J.8
Macdonald, R.L.9
Sigel, E.10
-
8
-
-
19944380200
-
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
-
DOI 10.1016/j.neubiorev.2005.03.009, PII S0149763405000382, Animal Models of Depression and Antidepressant Activity
-
J.F. Cryan, C. Mombereau, and A. Vassout The tail suspension test as a model for assessing antidepressant activity: a review of pharmacological and genetic studies in mice Neuroscience and Biobehavioral Reviews 29 2005 571 625 (Pubitemid 40755457)
-
(2005)
Neuroscience and Biobehavioral Reviews
, vol.29
, Issue.4-5
, pp. 571-625
-
-
Cryan, J.F.1
Mombereau, C.2
Vassout, A.3
-
9
-
-
35748966419
-
GABAA/Bz receptor subtypes as target for selective drugs
-
F. Da Settino, S. Taliani, M.L. Trincavelli, M. Montali, and C. Martini GABAA/Bz receptor subtypes as target for selective drugs Current Medicinal Chemistry 14 2007 2680 2701
-
(2007)
Current Medicinal Chemistry
, vol.14
, pp. 2680-2701
-
-
Da Settino, F.1
Taliani, S.2
Trincavelli, M.L.3
Montali, M.4
Martini, C.5
-
10
-
-
27544460357
-
A receptor extracellular and transmembrane domains: Important insights in pharmacology and function
-
DOI 10.1124/mol.105.015982
-
M. Ernst, S. Bruckner, S. Boresch, and W. Sieghart The comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function Molecular Pharmacology 68 2005 1291 1300 (Pubitemid 41539985)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.5
, pp. 1291-1300
-
-
Ernst, M.1
Bruckner, S.2
Boresch, S.3
Sieghart, W.4
-
11
-
-
3542999087
-
Die pharmakologische Wertbestimmung des Baldrians
-
F. Haffner Die pharmakologische Wertbestimmung des Baldrians Munchener Medizinische Wochenschrift 7 1929 271 272
-
(1929)
Munchener Medizinische Wochenschrift
, vol.7
, pp. 271-272
-
-
Haffner, F.1
-
12
-
-
37549018503
-
Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties
-
DOI 10.1016/j.phymed.2007.11.027, PII S0944711307002942
-
M. Hattesohl, B. Feistel, H. Sievers, R. Lehnfeld, M. Hegger, and H. Winterhoff Extracts of Valeriana officinalis L. s.I. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties Phytomedicine 15 2008 2 15 (Pubitemid 50021760)
-
(2008)
Phytomedicine
, vol.15
, Issue.1-2
, pp. 2-15
-
-
Hattesohl, M.1
Feistel, B.2
Sievers, H.3
Lehnfeld, R.4
Hegger, M.5
Winterhoff, H.6
-
14
-
-
34547229341
-
A receptors: Molecular mechanism and subunit specificity
-
DOI 10.1016/j.neuropharm.2007.04.018, PII S002839080700127X
-
S. Khom, I. Baburin, E. Timin, A. Hohaus, G. Trauner, B. Kopp, and S. Hering Valerenic acid potentiates and inhibits GABAA receptors: molecular mechanism and subunit specificity Neuropharmacology 53 1 2007 178 187 (Pubitemid 47125958)
-
(2007)
Neuropharmacology
, vol.53
, Issue.1
, pp. 178-187
-
-
Khom, S.1
Baburin, I.2
Timin, E.3
Hohaus, A.4
Trauner, G.5
Kopp, B.6
Hering, S.7
-
15
-
-
77955791538
-
Valerenic acid derivatives as novel subunit-selective ligands - In vitro and in vivo characterization
-
S. Khom, B. Strommeier, J. Ramharter, T. Schwarz, C. Shwarzer, T. Erker, G.F. Ecker, J. Mulzer, and S. Hering Valerenic acid derivatives as novel subunit-selective ligands - in vitro and in vivo characterization British Journal of Pharmacology 161 1 2010 65 78
-
(2010)
British Journal of Pharmacology
, vol.161
, Issue.1
, pp. 65-78
-
-
Khom, S.1
Strommeier, B.2
Ramharter, J.3
Schwarz, T.4
Shwarzer, C.5
Erker, T.6
Ecker, G.F.7
Mulzer, J.8
Hering, S.9
-
16
-
-
43249098580
-
A receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes
-
DOI 10.1055/s-2008-1074491
-
H.J. Kim, I. Baburin, S. Khom, S. Hering, and M. Hamburger HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two electrode voltage clamp assay on Xenopus oocytes Planta Medica 74 2008 521 526 (Pubitemid 351655969)
-
(2008)
Planta Medica
, vol.74
, Issue.5
, pp. 521-526
-
-
Hyun, J.K.1
Baburin, I.2
Khom, S.3
Hering, S.4
Hamburger, M.5
-
17
-
-
0035930485
-
A receptor β3 subunit eliminates the hypnotic actions of oleamide in mice
-
A.D. Laposky, G.E. Homanics, A. Basile, and W.B. Mendelson Deletion of the GABA(A) receptor beta 3 subunit eliminates the hypnotic actions of oleamide in mice Neuroreport 12 2001 4143 4147 (Pubitemid 33152468)
-
(2001)
NeuroReport
, vol.12
, Issue.18
, pp. 4143-4147
-
-
Laposky, A.D.1
Homanics, G.E.2
Basile, A.3
Mendelson, W.B.4
-
18
-
-
33748925413
-
GABA(A) receptor diversity and pharmacology
-
H. Möhler GABA(A) receptor diversity and pharmacology Cell and Tissue Research 326 2006 505 516
-
(2006)
Cell and Tissue Research
, vol.326
, pp. 505-516
-
-
Möhler, H.1
-
19
-
-
77952292512
-
Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats
-
K. Murphy, Z.J. Kubin, J.N. Shepherd, and R.H. Ettinger Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats Phytomedicine 17 2010 674 678
-
(2010)
Phytomedicine
, vol.17
, pp. 674-678
-
-
Murphy, K.1
Kubin, Z.J.2
Shepherd, J.N.3
Ettinger, R.H.4
-
20
-
-
33646853535
-
Chemical fingerprinting of valerian species: Simultaneous determination of valerenic acids, flavonoids, and phenylpropanoids using liquid chromatography with ultraviolet detection
-
A. Navarrete, B. Avula, and Y.W. Choi Chemical fingerprinting of valerian species: simultaneous determination of valerenic acids, flavonoids, and phenylpropanoids using liquid chromatography with ultraviolet detection Journal of AOAC International 89 2006 8 18
-
(2006)
Journal of AOAC International
, vol.89
, pp. 8-18
-
-
Navarrete, A.1
Avula, B.2
Choi, Y.W.3
-
21
-
-
54049137689
-
Internationale Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acid A receptors: Classification on the basis of subunit composition, pharmacology, and function. Update
-
R.W. Olsen, and W. Sieghart Internationale Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acid A receptors: classification on the basis of subunit composition, pharmacology, and function. Update Pharmacological Review 60 3 2008 242 260
-
(2008)
Pharmacological Review
, vol.60
, Issue.3
, pp. 242-260
-
-
Olsen, R.W.1
Sieghart, W.2
-
22
-
-
78751497286
-
The GABAA receptor α + β-interface: A novel target for subtype selective drugs
-
J. Ramerstorfer, R. Furtmüller, I. Sarto-Jackson, Z. Varagic, and W. Siehart The GABAA receptor α + β-interface: a novel target for subtype selective drugs Journal of Neuroscience 31 2011 870 877
-
(2011)
Journal of Neuroscience
, vol.31
, pp. 870-877
-
-
Ramerstorfer, J.1
Furtmüller, R.2
Sarto-Jackson, I.3
Varagic, Z.4
Siehart, W.5
-
23
-
-
0030733915
-
Animal models of 'anxiety': Where next?
-
R.J. Rodgers Animal models of anxiety: where next? Behavioural Pharmacology 8 1997 477 496 (Pubitemid 27504695)
-
(1997)
Behavioural Pharmacology
, vol.8
, Issue.6-7
, pp. 477-496
-
-
Rodgers, R.J.1
-
24
-
-
33750475904
-
A receptors as targets for novel anxiolytic drugs
-
DOI 10.1080/15622970600868525, PII Q50R2W35240H4W87
-
R. Rupprecht, D. Eser, P. Zwanzger, and H.J. Möller GABAA receptors as targets for novel anxiolytic drugs The World Journal of Biological Psychiatry 7 2006 231 237 (Pubitemid 44650532)
-
(2006)
World Journal of Biological Psychiatry
, vol.7
, Issue.4
, pp. 231-237
-
-
Rupprecht, R.1
Eser, D.2
Zwanzger, P.3
Moller, H.-J.4
-
25
-
-
35348914265
-
A-receptors
-
DOI 10.1002/ptr.2197
-
K. Sichardt, Z. Vissiennon, U. Koetter, A. Brattström, and K. Nieber Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosines A1- and GABAA receptors Phytotherapy Research 21 2007 932 937 (Pubitemid 47582766)
-
(2007)
Phytotherapy Research
, vol.21
, Issue.10
, pp. 932-937
-
-
Sichardt, K.1
Vissiennon, Z.2
Koetter, U.3
Brattstrom, A.4
Nieber, K.5
-
26
-
-
0028981088
-
Structure and pharmacology of γ-aminobutyric acid A receptor subtypes
-
W. Sieghart Structure and pharmacology of γ-aminobutyric acid A receptor subtypes Pharmacological Review 47 1995 181 234
-
(1995)
Pharmacological Review
, vol.47
, pp. 181-234
-
-
Sieghart, W.1
-
27
-
-
84859913795
-
A novel GABAA receptor pharmacology: Drugs interacting with the α + β-interface
-
10.1111/j.1476-5381.2011.01779.x Nov. 10 (Epub ahead of print)
-
W. Sieghart, J. Ramerstorfer, I. Sarto-Jackson, Z. Varagic, and M. Ernst A novel GABAA receptor pharmacology: drugs interacting with the α + β-interface British Journal of Pharmacology 2011 10.1111/j.1476-5381.2011. 01779.x Nov. 10 (Epub ahead of print)
-
(2011)
British Journal of Pharmacology
-
-
Sieghart, W.1
Ramerstorfer, J.2
Sarto-Jackson, I.3
Varagic, Z.4
Ernst, M.5
-
28
-
-
0021990491
-
The tail suspension test: A new method for screening antidepressants in mice
-
DOI 10.1007/BF00428203
-
l. Steru, R. Chermat, B. Thierry, and P. Simon The tail suspension test: a new method for screening antidepressants in mice Psychopharmacology 85 1985 367 370 (Pubitemid 15123115)
-
(1985)
Psychopharmacology
, vol.85
, Issue.3
, pp. 367-370
-
-
Steru, L.1
Chermat, R.2
Thierry, B.3
Simon, P.4
-
29
-
-
39149114366
-
A receptors by valerian extracts is related to the content of valerenic acid
-
DOI 10.1055/s-2007-993761
-
G. Trauner, S. Khom, I. Baburin, B. Benedek, S. Hering, and B. Kopp Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid Planta Medica 74 2008 19 24 (Pubitemid 351251378)
-
(2008)
Planta Medica
, vol.74
, Issue.1
, pp. 19-24
-
-
Trauner, G.1
Khom, S.2
Baburin, I.3
Benedek, B.4
Hering, S.5
Kopp, B.6
-
30
-
-
1642541871
-
The Gamma-Aminobutyric Acidergic Effects of Valerian and Valerenic Acid on Rat Brainstem Neuronal Activity
-
C.S. Yuan, S. Mehendale, Y. Xiao, H.H. Aung, J.T. Xie, and M.K. Ang-Lee The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity Anesthesia & Analgesia 98 2 2004 353 358 (Pubitemid 38129379)
-
(2004)
Anesthesia and Analgesia
, vol.98
, Issue.2
, pp. 353-358
-
-
Yuan, C.-S.1
Mehendale, S.2
Xiao, Y.3
Aung, H.H.4
Xie, J.-T.5
Ang-Lee, M.K.6
|