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Volumn 17, Issue 8-9, 2010, Pages 674-678

Valeriana officinalis root extracts have potent anxiolytic effects in laboratory rats

Author keywords

anxiolytic; benzodiazepine; elevated plus maze; GABA; valerenic acid; Valeriana officinalis

Indexed keywords

4 AMINOBUTYRIC ACID; ALCOHOL; DIAZEPAM; VALERIAN; VALERIC ACID;

EID: 77952292512     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.10.020     Document Type: Article
Times cited : (120)

References (15)
  • 1
    • 33745698164 scopus 로고    scopus 로고
    • Increased brain uptake and brain to blood efflux transport of 14C-GABA in spontaneously hypertensive rats
    • Al-Awadi M., Pavlik A., and Al-Sarraf H. Increased brain uptake and brain to blood efflux transport of 14C-GABA in spontaneously hypertensive rats. Life Sci. 79 9 (2006) 847-853
    • (2006) Life Sci. , vol.79 , Issue.9 , pp. 847-853
    • Al-Awadi, M.1    Pavlik, A.2    Al-Sarraf, H.3
  • 2
    • 36549072427 scopus 로고    scopus 로고
    • Effects of traditionally used anxiolytic botanicals of enzymes of the γ-aminobutyric acid (GABA) system
    • Awad R., Levac D., Cybulska P., Merali Z., Trudeau V.L., and Arnason J.T. Effects of traditionally used anxiolytic botanicals of enzymes of the γ-aminobutyric acid (GABA) system. Can. J. Phys. Pharmacol. 85 9 (2007) 933-942
    • (2007) Can. J. Phys. Pharmacol. , vol.85 , Issue.9 , pp. 933-942
    • Awad, R.1    Levac, D.2    Cybulska, P.3    Merali, Z.4    Trudeau, V.L.5    Arnason, J.T.6
  • 5
    • 0034098748 scopus 로고    scopus 로고
    • Critical evaluation of the effect of valerian extract on sleep structure and sleep quality
    • Donath F., Quispe S., Diefenbach K., Maurer A., Fietze I., and Roots I. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality. Pharmacopsychiatry 33 2 (2000) 47-53
    • (2000) Pharmacopsychiatry , vol.33 , Issue.2 , pp. 47-53
    • Donath, F.1    Quispe, S.2    Diefenbach, K.3    Maurer, A.4    Fietze, I.5    Roots, I.6
  • 6
    • 37549018503 scopus 로고    scopus 로고
    • Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties
    • Hattesohl M., Feistel B., Sievers H., Lehnfeld R., Hegger M., and Winterhoff H. Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties. Phytomedicine 15 1-2 (2008) 2-15
    • (2008) Phytomedicine , vol.15 , Issue.1-2 , pp. 2-15
    • Hattesohl, M.1    Feistel, B.2    Sievers, H.3    Lehnfeld, R.4    Hegger, M.5    Winterhoff, H.6
  • 7
    • 0021962440 scopus 로고
    • Central nervous depressant activity of valerenic acid in the mouse
    • Hendriks H., Bos R., Woerdenbag H.J., and Koster S. Central nervous depressant activity of valerenic acid in the mouse. Planta Med. 1 (1985) 28-31
    • (1985) Planta Med. , vol.1 , pp. 28-31
    • Hendriks, H.1    Bos, R.2    Woerdenbag, H.J.3    Koster, S.4
  • 9
    • 2042537321 scopus 로고    scopus 로고
    • An intrinsic gamma-aminobutyric acid (GABA)ergic system in the adrenal cortex: findings from human and rat adrenal glands and the NCI-H295R cell line
    • Metzeler K., Agoston A., and Gratzl M. An intrinsic gamma-aminobutyric acid (GABA)ergic system in the adrenal cortex: findings from human and rat adrenal glands and the NCI-H295R cell line. Endocrinology 145 5 (2004) 2402-2411
    • (2004) Endocrinology , vol.145 , Issue.5 , pp. 2402-2411
    • Metzeler, K.1    Agoston, A.2    Gratzl, M.3
  • 10
    • 0037031791 scopus 로고    scopus 로고
    • Interaction of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors
    • Müller C., Schumacher B., Brattström A., Abourashed E.A., and Koetter U. Interaction of valerian extracts and a fixed valerian-hop extract combination with adenosine receptors. Life Sci. 71 16 (2002) 1939-1949
    • (2002) Life Sci. , vol.71 , Issue.16 , pp. 1939-1949
    • Müller, C.1    Schumacher, B.2    Brattström, A.3    Abourashed, E.A.4    Koetter, U.5
  • 11
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Pellow S., Chopin P., File S., and Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods 14 3 (1985) 149-167
    • (1985) J. Neurosci. Methods , vol.14 , Issue.3 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.3    Briley, M.4
  • 12
    • 0023923638 scopus 로고
    • The role of adenosine in the central actions of the benzodiazepines
    • Phillis J.W., and O'Regan M.H. The role of adenosine in the central actions of the benzodiazepines. Prog. Neuro-Psychopharmacol. Bio. Psychiatry 12 4 (1988) 384-404
    • (1988) Prog. Neuro-Psychopharmacol. Bio. Psychiatry , vol.12 , Issue.4 , pp. 384-404
    • Phillis, J.W.1    O'Regan, M.H.2
  • 13
    • 33644543348 scopus 로고    scopus 로고
    • Prevalence and incidence studies of anxiety disorders: a systematic review of the literature
    • Somers J.M., Goldner E.M., Waraich P., and Hsu L. Prevalence and incidence studies of anxiety disorders: a systematic review of the literature. Can. J. Psychiatry 51 2 (2006) 100-112
    • (2006) Can. J. Psychiatry , vol.51 , Issue.2 , pp. 100-112
    • Somers, J.M.1    Goldner, E.M.2    Waraich, P.3    Hsu, L.4
  • 14
    • 0036240369 scopus 로고    scopus 로고
    • Benzodiazepine side-effects: from the bench to the clinic
    • Stewart S.H., and Westra H.A. Benzodiazepine side-effects: from the bench to the clinic. Cur. Pharmaceut. Des. 8 1 (2002) 1-3
    • (2002) Cur. Pharmaceut. Des. , vol.8 , Issue.1 , pp. 1-3
    • Stewart, S.H.1    Westra, H.A.2
  • 15
    • 0028257965 scopus 로고
    • The modulatory action of loreclezole at the γ-aminobutyric acid type A receptor is determined by a single amino acid in the β2 and β3 subunit
    • Wingrove P.B., Wafford K.A., Bain C., and Witting P.J. The modulatory action of loreclezole at the γ-aminobutyric acid type A receptor is determined by a single amino acid in the β2 and β3 subunit. Proc. Natl. Acad. Sci. 91 (1994) 4569-4573
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 4569-4573
    • Wingrove, P.B.1    Wafford, K.A.2    Bain, C.3    Witting, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.