The effect of water plasticization on the molecular mobility and crystallization tendency of amorphous disaccharides

Pharmaceutical Research

Volumn 29, Issue 10, 2012, Pages 2684-2697

  Heljo, Ville Petteri ^a   Nordberg, Antti ^a   Tenho, Mikko ^b   Virtanen, Tommi ^a   Jouppila, Kirsi ^a   Salonen, Jarno ^b   Maunu, Sirkka Liisa ^a   Juppo, Anne Mari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Amorphous; Crystallization; Disaccharide; Mobility; Water

Indexed keywords

CELLOBIOSE; DISACCHARIDE; MELIBIOSE; SUCROSE; TREHALOSE; WATER;

ARTICLE; BRUNAUER EMMETT TELLER EQUATION; CRYSTALLIZATION; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; GORDON TAYLOR EQUATION; HUMIDITY; MATHEMATICAL MODEL; MOLECULAR MECHANICS; MOLECULAR MOBILITY; PHYSICAL PHENOMENA; PLASTICITY; PRIORITY JOURNAL; REDUCED CRYSTALLIZATION TEMPERATURE; TEMPERATURE; THERMOSTABILITY;

ABSORPTION; CRYSTALLIZATION; DISACCHARIDES; DRUG STORAGE; FREEZE DRYING; HUMIDITY; PLASTICIZERS; TRANSITION TEMPERATURE; WATER;

EID: 84866731586     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0658-4     Document Type: Article

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