Crystallization of sucrose glass under ambient conditions: Evaluation of crystallization rate and unusual melting behavior of resultant crystals

Journal of Pharmaceutical Sciences

Volumn 95, Issue 6, 2006, Pages 1354-1363

  Kawakami, Kohsaku ^a,b   Miyoshi, Kyoko ^a   Tamura, Naomi ^a   Yamaguchi, Tohru ^a   Ida, Yasuo ^a  

^a SHIONOGI AND CO LTD   (Japan)

^b BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Annealing; Avrami Erofeev equation; Crystal defects; Crystallization; Desorption

Indexed keywords

SUCROSE; WATER;

ARTICLE; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; DESORPTION; ENVIRONMENTAL TEMPERATURE; LOW TEMPERATURE; MELTING POINT; MICROCALORIMETRY; MOLECULAR WEIGHT; POWDER DIFFRACTION; SOLID STATE; WATER ABSORPTION; X RAY DIFFRACTION;

EID: 33745018390     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20458     Document Type: Article

References (30)

1. Rodríguez-Hornedo N, Murphy D. 1999. Significance of controlling crystallization mechanisms and kinetics in pharmaceutical systems. J Pharm Sci 88:651-660.
2. 3 System. J Phys Chem 95:7050-7054.
3. Zhou D, Schmitt EA, Zhang GG, Law D, Vyazovkin S, Wight CA, Grant DJW. 2003. Crystallization kinetics of amorphous nifedipine studied by model-fitting and model-free approaches. J Pharm Sci 92:1779-1792.
4. Vyazovkin S, Wight CA. 1997. Isothermal and nonisothermal reaction kinetics in solids: In search of ways toward consensus. J Phys Chem A 101:8279-8284.
5. Ray HS. 1990. Some factors that lead to uncertainties in kinetic studies in metallurgy. J Thermal Anal 36:743-764.
6. Ledwidge MT, Corrigan OI. 1997. Effects of environmental factors on the dehydration of diclofenac HEP dihydrate and theophylline monohydrate. Int J Pharm 147:41-49.
7. Cheng SZD, Pan R, Wunderlich B. 1988. Thermal analysis of poly(butylene terephthalate) for heat capacity, rigid-amorphous content, and transition behavior. Makromol Chem 189:2443-2458.
8. Gupta VB. 2002. Heat setting. J Appl Polym Sci 83:586-609.
9. Yasuniwa M, Tsubakihara S, Fujioka T. 2003. X-ray and DSC studies on the melt-crystallization process of poly(butylene naphthalate). Thermochim Acta 396:75-78.
10. Chiou WL, Kyle LE. 1979. Differential thermal, solubility, and aging studies on various sources of digoxin and digitoxin powder: Biopharmaceutical implications. J Pharm Sci 68:1224-1229.
11. Hodge IM. 1994. Enthalpy relaxation and recovery in amorphous materials. J Non-Cryst Solids 169: 211-266.
12. Angell CA, Ngai KL, McKenna GB, McMillan PF, Martin SW. 2000. Relaxation in glassforming liquids and amorphous solids. Appl Phys Rev 88:3113-3157.
13. Kawakami K, Ida Y. 2003. Direct observation of the enthalpy relaxation and the recovery processes of maltose-based amorphous formulation by isothermal microcalorimetry. Pharm Res 20:1430-1436.
14. Kawakami K, Pikal MJ. 2005. Calorimetric investigation of the structural relaxation of amorphous materials: Evaluating validity of the methodologies. J Pharm Sci 94:948-965.
15. Shamblin S, Tang X, Chang L, Hancock BC, Pikal MJ. 1999. Characterization of the time scales of molecular motion in pharmaceutically important glasses. J Phys Chem B 103:4113-4121.
16. Kawakami K. Numa T, Ida Y. 2002. Assessment of amorphous content by microcalorimetry. J Pharm Sci 91:417-423.
17. Lu X, Hay JN. 2000. The effect of physical aging on the rates of cold crystallization of poly(ethylene terephthalate). Polymer 41:7427-7436.
18. Hirayama F, Wang Z, Uekama K. 1994. Effect of 2-hydroxypropyl-β- cyclodextrin on crystallization and polymorphic transition of nifedipine in solid state. Pharm Res 11:1766-1770.
19. Gordon M, Taylor JS. 1952. Ideal copolymers and the second-order transitions of synthetic rubbers. I. Non-crystalline copolymers. J Appl Chem 2:493-500.
20. Hancock BC, Zografi G. 1994. The relationship between the glass transition temperature and the water content of amorphous pharmaceutical solids. Pharm Res 11:471-477.
21. Hancock BC, Zografi G. 1997. Characteristics and significance of the amorphous state in pharmaceutical systems. J Pharm Sci 86:1-12.
22. Hancock BC, Dalton CR. 1999. The effect of temperature on water vapor sorption by some amorphous pharmaceutical sugars. Pharm Dev Technol 4:125-131.
23. Kedward CJ, Macnaughtan W, Blanshard JMV, Mitchell JR. 1998. Crystallization kinetics of lactose and sucrose based on isothermal differential scanning calorimetry. J Food Sci 63:192-197.
24. Carstensen JT, Scoik KV. 1990. Amorphous-to-crystalline transformation of sucrose. Pharm Res 7:1278-1281.
25. Stubberud L, Forbes RT. 1998. The use of gravimetry for the study of the effect of additives on the moisture-induced recrystallization of amorphous lactose. Int J Pharm 163:145-156.
26. Sheng J, Venkatesh GM, Duddu SP, Grant DJW. 1999. Dehydration behavior of eprosartan mesylate dihydrate. J Pharm Sci 88:1021-1029.
27. Zhu H, Grant DJW. 2001. Dehydration behavior of nedocromil magnesium pentahydrate. Int J Pharm 215:251-262.
28. Ono M, Tozuka Y, Oguchi T, Yamamoto K. 2001. Effects of dehydration temperatures on moisture absorption and dissolution behavior of theophylline. Chem Pharm Bull 49:1526-1530.
29. Sussich F, Urbani R, Princivalle F, Cesàro A. 1998. Polymorphic amorphous and crystalline forms of trehalose. J Am Chem Soc 120:7893-7899.
30. McGarvey OS, Kett VL, Craig DQM. 2003. An investigation into the crystallization of α,α-trehalose from the amorphous state. J Phys Chem B 107:6614-6620.