Bystander effect in glioma suicide gene therapy using bone marrow stromal cells

Stem Cell Research

Volumn 9, Issue 3, 2012, Pages 270-276

  Li, Shaoyi ^a,b   Gu, Chunyu ^a,b   Gao, Yun ^a   Amano, Shinji ^a   Koizumi, Shinichiro ^a   Tokuyama, Tsutomu ^a   Namba, Hiroki ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR;

ADULT; ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MARROW STROMAL CELL; BYSTANDER EFFECT; CELL MIGRATION; FEMALE; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; STROMA CELL; SUICIDE GENE THERAPY;

ANIMALS; BYSTANDER EFFECT; CELL LINE, TUMOR; CELLS, CULTURED; FEMALE; GANCICLOVIR; GENES, TRANSGENIC, SUICIDE; GENETIC THERAPY; GENETIC VECTORS; GLIOMA; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; RATS; RATS, SPRAGUE-DAWLEY; SIMPLEXVIRUS; SPECIES SPECIFICITY; THYMIDINE KINASE; TRANSDUCTION, GENETIC; YOUNG ADULT;

MUS MUSCULUS; RATTUS; SIMPLEXVIRUS;

EID: 84866718897     PISSN: 18735061     EISSN: 18767753     Source Type: Journal    
DOI: 10.1016/j.scr.2012.08.002     Document Type: Article

References (27)

1. Aboody K.S., Brown A., Rainov N.G., Bower K.A., Liu S., Yang W., Small J.E., Herrlinger U., Ourednik V., Black P.M., Breakefield X.O., Snyder E.Y. Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:12846-12851.
2. Amano S., Li S., Gu C., Gao Y., Koizumi S., Yamamoto S., Terakawa S., Namba H. Use of genetically engineered bone marrow-derived mesenchymal stem cells for glioma gene therapy. Int. J. Oncol. 2009, 35:1265-1270.
3. Benedetti S., Pirola B., Pollo B., Magrassi L., Bruzzone M.G., Rigamonti D., Galli R., Selleri S., DiMeco F., DeFraja C., Vescovi A., Cattaneo E., Finocchiaro G. Gene therapy of experimental brain tumors using neural progenitor cells. Nat. Med. 2000, 6:447-450.
4. Culver K.W., Ram Z., Walbridge S., Ishii H., Oldfield E.H., Blaese R.M. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992, 256:1550-1552.
5. DeAngelis L.M. Brain tumors. N. Engl. J. Med. 2001, 344:114-123.
6. Dilber M.S., Abedi M.R., Christensson B., Björkstrand B., Kidder G.M., Naus C.C., Gahrton G., Smith C.I. Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo. Cancer Res. 1997, 57:1523-1528.
7. Elshami A.A., Saavedra A., Zhang H., Kucharczuk J.C., Spray D.C., Fishman G.I., Amin K.M., Kaiser L.R., Albelda S.M. Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Ther. 1886, 3:85-92.
8. Gu C., Li S., Tokuyama T., Yokota N., Namba H. Therapeutic effect of genetically engineered mesenchymal stem cells in rat experimental leptomeningeal glioma model. Cancer Lett. 2010, 291:256-262.
9. Koizumi S., Gu C., Amano S., Yamamoto S., Ihara H., Tokuyama T., Namba H. Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors. Oncol. Lett. 2011, 2:283-288.
10. Lee J., Elkahloun A.G., Messina S.A., Ferrari N., Xi D., Smith C.L., Cooper R., Albert P.S., Fine H.A. Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: a potential antiglioma cellular vector. Cancer Res. 2003, 63:8877-8889.
11. Li S., Tokuyama T., Yamamoto J., Koide M., Yokota N., Namba H. Bystander effect-mediated gene therapy of gliomas using genetically engineered neural stem cells. Cancer Gene Ther. 2005, 12:600-607.
12. Li S., Tokuyama T., Yamamoto J., Koide M., Yokota N., Namba H. Potent bystander effect in suicide gene therapy using neural stem cells transduced with herpes simplex virus thymidine kinase gene. Oncology 2005, 69:503-508.
13. Li S., Gao Y., Tokuyama T., Yamamoto J., Yokota N., Yamamoto S., Terakawa S., Kitagawa M., Namba H. Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites. Cancer Lett. 2007, 251:220-227.
14. Mesnil M., Piccoli C., Tiraby G., Willecke K., Yamasaki H. Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:1831-1835.
15. Mohanam S., Sawaya R., McCutcheon I., Ali-Osman F., Boyd D., Rao J.S. Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. Cancer Res. 1993, 53:4143-4147.
16. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
17. Nakamizo A., Marini F., Amano T., Khan A., Studeny M., Gumin J., Chen J., Hentschel S., Vecil G., Dembinski J., Andreeff M., Lang F.F. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res. 2005, 65:3307-3318.
18. Namba H., Tagawa M., Miyagawa T., Iwadate Y., Sakiyama S. Treatment of rat experimental brain tumors by herpes simplex virus thymidine kinase gene-transduced allogeneic tumor cells and ganciclovir. Cancer Gene Ther. 2000, 7:947-953.
19. Namba H., Iwadate Y., Kawamura K., Sakiyama S., Tagawa M. Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells. Cancer Gene Ther. 2001, 8:414-420.
20. Rainov N.G. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther. 2000, 11:2389-2401.
21. Ram Z., Culver K.W., Oshiro E.M., Viola J.J., DeVroom H.L., Otto E., Long Z., Chiang Y., McGarrity G.J., Muul L.M., Katz D., Blaese R.M., Oldfield E.H. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat. Med. 1997, 3:1354-1361.
22. Stewart L.A. Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet 2002, 359:1011-1018.
23. Stupp R., Mason W.P., Bent M.J.v.d, Weller M., Fisher B., Taphoorn M.J., Belanger K., Brandes A.A., Marosi C., Bogdahn U., Curschmann J., Janzer R.C., Ludwin S.K., Gorlia T., Allgeier A., Lacombe D., Cairncross J.G., Eisenhauer E., Mirimanoff R.O. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352:987-996. European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups, National Cancer Institute of Canada Clinical Trials Group.
24. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
25. Vrionis F.D., Wu J.K., Qi P., Waltzman M., Cherington V., Spray D.C. The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Ther. 1997, 4:577-585.
26. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., Nie J., Jonsdottir G.A., Ruotti V., Stewart R., Slukvin I.I., Thomson J.A. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
27. Ziu M., Schmidt N.O., Cargioli T.G., Aboody K.S., Black P.M., Carroll R.S. Glioma-produced extracellular matrix influences brain tumor tropism of human neural stem cells. J. Neurooncol. 2006, 79:125-133.