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Volumn 35, Issue 6, 2009, Pages 1265-1270

Use of genetically engineered bone marrow-derived mesenchymal stem cells for glioma gene therapy

Author keywords

Bystander effect; Glioma; Herpes simplex virus thymidine kinase; Mesenchymal stem cell; Suicide gene therapy

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; ANTIVIRUS AGENT;

EID: 73949139195     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000443     Document Type: Article
Times cited : (55)

References (39)
  • 1
    • 0035843243 scopus 로고    scopus 로고
    • Brain tumors
    • De Angelis LM: Brain tumors. N Engl J Med 344: 114-123, 2001.
    • (2001) N Engl J Med , vol.344 , pp. 114-123
    • De Angelis, L.M.1
  • 2
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • Lefranc F, Brotchi J and Kiss R: Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol 23: 2411-2422, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 3
    • 0037161024 scopus 로고    scopus 로고
    • Chemotherapy in adult high-grade glioma: A systematic review and meta-analysis of individual patient data from 12 randomised trials
    • Stewart LA: Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet 359: 1011-1018, 2002.
    • (2002) Lancet , vol.359 , pp. 1011-1018
    • Stewart, L.A.1
  • 4
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH and Blaese RM: In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 256: 1550-1552, 1992.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 5
    • 33646763193 scopus 로고    scopus 로고
    • Clinical trials of gene therapy, virotherapy, and immunotherapy for malignant gliomas
    • Barzon L, Zanusso M, Colombo F and Palu G: Clinical trials of gene therapy, virotherapy, and immunotherapy for malignant gliomas. Cancer Gene Ther 13: 539-554, 2006.
    • (2006) Cancer Gene Ther , vol.13 , pp. 539-554
    • Barzon, L.1    Zanusso, M.2    Colombo, F.3    Palu, G.4
  • 6
    • 0034619328 scopus 로고    scopus 로고
    • Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
    • Aboody KS, Brown A, Rainov NG, et al: Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci USA 97: 12846-12851, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12846-12851
    • Aboody, K.S.1    Brown, A.2    Rainov, N.G.3
  • 7
    • 0037108871 scopus 로고    scopus 로고
    • The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma
    • Ehtesham M, Kabos P, Kabosova A, Neuman T, Black KL and Yu JS: The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma. Cancer Res 62: 5657-5663, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5657-5663
    • Ehtesham, M.1    Kabos, P.2    Kabosova, A.3    Neuman, T.4    Black, K.L.5    Yu, J.S.6
  • 8
    • 0347624005 scopus 로고    scopus 로고
    • Proliferation, migration, and differentiation of human neural stem/progenitor cells after transplantation into a rat model of traumatic brain injury
    • Wennersten A, Meier X, Holmin S, Wahlberg L and Mathiesen T: Proliferation, migration, and differentiation of human neural stem/progenitor cells after transplantation into a rat model of traumatic brain injury. J Neurosurg 100: 88-96, 2004.
    • (2004) J Neurosurg , vol.100 , pp. 88-96
    • Wennersten, A.1    Meier, X.2    Holmin, S.3    Wahlberg, L.4    Mathiesen, T.5
  • 9
    • 34247592355 scopus 로고    scopus 로고
    • Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites
    • Li S, Gao Y, Tokuyama T, et al: Genetically engineered neural stem cells migrate and suppress glioma cell growth at distant intracranial sites. Cancer Lett 251: 220-227, 2007.
    • (2007) Cancer Lett , vol.251 , pp. 220-227
    • Li, S.1    Gao, Y.2    Tokuyama, T.3
  • 10
    • 22044433684 scopus 로고    scopus 로고
    • Bystander effect-mediated gene therapy of gliomas using genetically engineered neural stem cells
    • Li S, Tokuyama T, Yamamoto J, Koide M, Yokota N and Namba H: Bystander effect-mediated gene therapy of gliomas using genetically engineered neural stem cells. Cancer Gene Ther 12: 600-607, 2005.
    • (2005) Cancer Gene Ther , vol.12 , pp. 600-607
    • Li, S.1    Tokuyama, T.2    Yamamoto, J.3    Koide, M.4    Yokota, N.5    Namba, H.6
  • 11
    • 0346059589 scopus 로고    scopus 로고
    • Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: A potential antiglioma cellular vector
    • Lee J, Elkahloun AG, Messina SA, et al: Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: a potential antiglioma cellular vector. Cancer Res 63: 8877-8889, 2003.
    • (2003) Cancer Res , vol.63 , pp. 8877-8889
    • Lee, J.1    Elkahloun, A.G.2    Messina, S.A.3
  • 12
    • 4243125420 scopus 로고    scopus 로고
    • Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model
    • Nakamura K, Ito Y, Kawano Y, et al: Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther 11: 1155-1164, 2004.
    • (2004) Gene Ther , vol.11 , pp. 1155-1164
    • Nakamura, K.1    Ito, Y.2    Kawano, Y.3
  • 13
    • 20244374417 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas
    • Nakamizo A, Marini F, Amano T, et al: Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 65: 3307-3318, 2005.
    • (2005) Cancer Res , vol.65 , pp. 3307-3318
    • Nakamizo, A.1    Marini, F.2    Amano, T.3
  • 14
    • 33645095181 scopus 로고    scopus 로고
    • Interleukin-23- expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma
    • Yuan X, Hu J, Belladonna ML, Black KL and Yu JS: Interleukin-23- expressing bone marrow-derived neural stem-like cells exhibit antitumor activity against intracranial glioma. Cancer Res 66: 2630-2638, 2006.
    • (2006) Cancer Res , vol.66 , pp. 2630-2638
    • Yuan, X.1    Hu, J.2    Belladonna, M.L.3    Black, K.L.4    Yu, J.S.5
  • 15
    • 38949113727 scopus 로고    scopus 로고
    • In vivo tracking of superparamagnetic iron oxide nanoparticle-labeled mesenchymal stem cell tropism to malignant gliomas using magnetic resonance imaging. Laboratory Investigation
    • Wu X, Hu J, Zhou L, et al: In vivo tracking of superparamagnetic iron oxide nanoparticle-labeled mesenchymal stem cell tropism to malignant gliomas using magnetic resonance imaging. Laboratory Investigation. J Neurosurg 108: 320-329, 2008.
    • (2008) J Neurosurg , vol.108 , pp. 320-329
    • Wu, X.1    Hu, J.2    Zhou, L.3
  • 16
    • 58149235124 scopus 로고    scopus 로고
    • Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas
    • Bexell D, Gunnarsson S, Tormin A, et al: Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. Mol Ther 17: 183-190, 2009.
    • (2009) Mol Ther , vol.17 , pp. 183-190
    • Bexell, D.1    Gunnarsson, S.2    Tormin, A.3
  • 17
    • 0029952922 scopus 로고    scopus 로고
    • Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging
    • Namba H, Iwadate Y, Tagawa M, et al: Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging. Hum Gene Ther 7: 1847-1852, 1996.
    • (1996) Hum Gene Ther , vol.7 , pp. 1847-1852
    • Namba, H.1    Iwadate, Y.2    Tagawa, M.3
  • 18
    • 0031976061 scopus 로고    scopus 로고
    • Bystander effect-mediated therapy of experimental brain tumor by genetically engineered tumor cells
    • Namba H, Tagawa M, Iwadate Y, Kimura M, Sueyoshi K and Sakiyama S: Bystander effect-mediated therapy of experimental brain tumor by genetically engineered tumor cells. Hum Gene Ther 9: 5-11, 1998.
    • (1998) Hum Gene Ther , vol.9 , pp. 5-11
    • Namba, H.1    Tagawa, M.2    Iwadate, Y.3    Kimura, M.4    Sueyoshi, K.5    Sakiyama, S.6
  • 19
    • 32044432090 scopus 로고    scopus 로고
    • Potent bystander effect in suicide gene therapy using neural stem cells transduced with herpes simplex virus thymidine kinase gene
    • Li S, Tokuyama T, Yamamoto J, Koide M, Yokota N and Namba H: Potent bystander effect in suicide gene therapy using neural stem cells transduced with herpes simplex virus thymidine kinase gene. Oncology 69: 503-508, 2005.
    • (2005) Oncology , vol.69 , pp. 503-508
    • Li, S.1    Tokuyama, T.2    Yamamoto, J.3    Koide, M.4    Yokota, N.5    Namba, H.6
  • 20
    • 0029815349 scopus 로고    scopus 로고
    • In vivo bystander effect in the intracranial model with rat glioma cells reflects the clonal difference of HSV-TK positive cells
    • Iwadate Y, Namba H, Tagawa M, Takenaga K, Sueyoshi K and Sakiyama S: In vivo bystander effect in the intracranial model with rat glioma cells reflects the clonal difference of HSV-TK positive cells. Int J Oncol 9: 521-525, 1996.
    • (1996) Int J Oncol , vol.9 , pp. 521-525
    • Iwadate, Y.1    Namba, H.2    Tagawa, M.3    Takenaga, K.4    Sueyoshi, K.5    Sakiyama, S.6
  • 21
    • 36749068983 scopus 로고    scopus 로고
    • Normal brain cells contribute to the bystander effect in suicide gene therapy of malignant glioma
    • Miletic H, Fischer YH, Giroglou T, et al: Normal brain cells contribute to the bystander effect in suicide gene therapy of malignant glioma. Clin Cancer Res 13: 6761-6768, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 6761-6768
    • Miletic, H.1    Fischer, Y.H.2    Giroglou, T.3
  • 22
    • 41149167018 scopus 로고    scopus 로고
    • Effects of iron oxide incorporation for long term cell tracking on MSC differentiation in vitro and in vivo
    • Farrell E, Wielopolski P, Pavljasevic P, et al: Effects of iron oxide incorporation for long term cell tracking on MSC differentiation in vitro and in vivo. Biochem Biophys Res Commun 369: 1076-1081, 2008.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 1076-1081
    • Farrell, E.1    Wielopolski, P.2    Pavljasevic, P.3
  • 23
    • 57349101092 scopus 로고    scopus 로고
    • Comparison between adenoviral and retroviral vectors for the transduction of the thymidine kinase PET reporter gene in rat mesenchymal stem cells
    • Roelants V, Labar D, De Meester C, et al: Comparison between adenoviral and retroviral vectors for the transduction of the thymidine kinase PET reporter gene in rat mesenchymal stem cells. J Nucl Med 49: 1836-1844, 2008.
    • (2008) J Nucl Med , vol.49 , pp. 1836-1844
    • Roelants, V.1    Labar, D.2    De Meester, C.3
  • 24
    • 33746781077 scopus 로고    scopus 로고
    • Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene
    • Xiong Z, Cheng Z, Zhang X, et al: Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene. J Nucl Med 47: 130-139, 2006.
    • (2006) J Nucl Med , vol.47 , pp. 130-139
    • Xiong, Z.1    Cheng, Z.2    Zhang, X.3
  • 25
    • 14644408765 scopus 로고    scopus 로고
    • Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography
    • Yaghoubi SS, Barrio JR, Namavari M, et al: Imaging progress of herpes simplex virus type 1 thymidine kinase suicide gene therapy in living subjects with positron emission tomography. Cancer Gene Ther 12: 329-339, 2005.
    • (2005) Cancer Gene Ther , vol.12 , pp. 329-339
    • Yaghoubi, S.S.1    Barrio, J.R.2    Namavari, M.3
  • 26
    • 0037429004 scopus 로고    scopus 로고
    • Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes
    • Jacobs AH, Winkeler A, Hartung M, et al: Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes. Hum Gene Ther 14: 277-297, 2003.
    • (2003) Hum Gene Ther , vol.14 , pp. 277-297
    • Jacobs, A.H.1    Winkeler, A.2    Hartung, M.3
  • 27
    • 67651011690 scopus 로고    scopus 로고
    • Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy
    • Uchibori R, Okada T, Ito T, et al: Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy. J Gene Med 11: 373-381, 2009.
    • (2009) J Gene Med , vol.11 , pp. 373-381
    • Uchibori, R.1    Okada, T.2    Ito, T.3
  • 28
    • 57149088465 scopus 로고    scopus 로고
    • Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma
    • Kim SM, Lim JY, Park SI, et al: Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. Cancer Res 68: 9614-9623, 2008.
    • (2008) Cancer Res , vol.68 , pp. 9614-9623
    • Kim, S.M.1    Lim, J.Y.2    Park, S.I.3
  • 29
    • 0036644833 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors
    • Studeny M, Marini F, Champlin R, Zompetta C, Fidler I and Andreeff M: Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 62: 3603-3608, 2002.
    • (2002) Cancer Res , vol.62 , pp. 3603-3608
    • Studeny, M.1    Marini, F.2    Champlin, R.3    Zompetta, C.4    Fidler, I.5    Andreeff, M.6
  • 30
    • 34447132890 scopus 로고    scopus 로고
    • Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy
    • Kucerova L, Altanerova V, Matuskova M, Tyciakova S and Altaner C: Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res 67: 6304-6313, 2007.
    • (2007) Cancer Res , vol.67 , pp. 6304-6313
    • Kucerova, L.1    Altanerova, V.2    Matuskova, M.3    Tyciakova, S.4    Altaner, C.5
  • 31
    • 34447506370 scopus 로고    scopus 로고
    • Microglia used as vehicles for both inducible thymidine kinase gene therapy and MRI contrast agents for glioma therapy
    • Ribot E, Bouzier-Sore AK, Bouchaud V, et al: Microglia used as vehicles for both inducible thymidine kinase gene therapy and MRI contrast agents for glioma therapy. Cancer Gene Ther 14: 724-737, 2007.
    • (2007) Cancer Gene Ther , vol.14 , pp. 724-737
    • Ribot, E.1    Bouzier-Sore, A.K.2    Bouchaud, V.3
  • 32
    • 34250768170 scopus 로고    scopus 로고
    • Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene
    • Miletic H, Fischer Y, Litwak S, et al: Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene. Mol Ther 15: 1373-1381, 2007.
    • (2007) Mol Ther , vol.15 , pp. 1373-1381
    • Miletic, H.1    Fischer, Y.2    Litwak, S.3
  • 33
    • 34250701074 scopus 로고    scopus 로고
    • Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines
    • Birnbaum T, Roider J, Schankin CJ, et al: Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines. J Neurooncol 83: 241-247, 2007.
    • (2007) J Neurooncol , vol.83 , pp. 241-247
    • Birnbaum, T.1    Roider, J.2    Schankin, C.J.3
  • 34
    • 39049182841 scopus 로고    scopus 로고
    • Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas
    • Robe PA, Nguyen-Khac MT, Lambert F, et al: Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas. Int J Oncol 30: 283-290, 2007.
    • (2007) Int J Oncol , vol.30 , pp. 283-290
    • Robe, P.A.1    Nguyen-Khac, M.T.2    Lambert, F.3
  • 35
    • 33646078796 scopus 로고    scopus 로고
    • Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy
    • Jimenez T, Fox WP, Naus CC, Galipeau J and Belliveau DJ: Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy. Cell Commun Adhes 13: 79-92, 2006.
    • (2006) Cell Commun Adhes , vol.13 , pp. 79-92
    • Jimenez, T.1    Fox, W.P.2    Naus, C.C.3    Galipeau, J.4    Belliveau, D.J.5
  • 36
    • 12844258193 scopus 로고    scopus 로고
    • Migratory neural stem cells for improved thymidine kinase-based gene therapy of malignant gliomas
    • Uhl M, Weiler M, Wick W, Jacobs AH, Weller M and Herrlinger U: Migratory neural stem cells for improved thymidine kinase-based gene therapy of malignant gliomas. Biochem Biophys Res Commun 328: 125-129, 2005.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 125-129
    • Uhl, M.1    Weiler, M.2    Wick, W.3    Jacobs, A.H.4    Weller, M.5    Herrlinger, U.6
  • 37
    • 85047698025 scopus 로고    scopus 로고
    • Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells
    • Burrows FJ, Gore M, Smiley WR, et al: Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells. Cancer Gene Ther 9: 87-95, 2002.
    • (2002) Cancer Gene Ther , vol.9 , pp. 87-95
    • Burrows, F.J.1    Gore, M.2    Smiley, W.R.3
  • 38
    • 0034887138 scopus 로고    scopus 로고
    • Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells
    • Namba H, Iwadate Y, Kawamura K, Sakiyama S and Tagawa M: Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells. Cancer Gene Ther 8: 414-420, 2001.
    • (2001) Cancer Gene Ther , vol.8 , pp. 414-420
    • Namba, H.1    Iwadate, Y.2    Kawamura, K.3    Sakiyama, S.4    Tagawa, M.5
  • 39
    • 33747854225 scopus 로고    scopus 로고
    • The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy
    • Hayashi K, Lee JB, Maitani Y, Toyooka N, Nemoto H and Hayashi T: The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy. J Gene Med 8: 1056-1067, 2006.
    • (2006) J Gene Med , vol.8 , pp. 1056-1067
    • Hayashi, K.1    Lee, J.B.2    Maitani, Y.3    Toyooka, N.4    Nemoto, H.5    Hayashi, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.