Insights into the role of magnesium triad in myo-inositol monophosphatase: Metal mechanism, substrate binding, and lithium therapy

Journal of Chemical Information and Modeling

Volumn 52, Issue 9, 2012, Pages 2398-2409

  Lu, Shaoyong ^a   Huang, Wenkang ^a   Li, Xiaobai ^a   Huang, Zhimin ^a   Liu, Xinyi ^a   Chen, Yingyi ^a   Shi, Ting ^a   Zhang, Jian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; CELL SIGNALING; COMPUTATIONAL CHEMISTRY; LITHIUM; METAL IONS; MOLECULAR DYNAMICS; MOLECULES; POLYOLS; QUANTUM THEORY; SUGARS;

CATALYTIC MECHANISMS; COMPUTATIONAL STUDIES; INORGANIC PHOSPHATES; MOLECULAR DYNAMICS SIMULATIONS; NUCLEOPHILIC ATTACK; PHOSPHATIDYLINOSITOL; SIGNALING PATHWAYS; THERAPEUTIC TARGETS;

MAGNESIUM COMPOUNDS;

INOSITOL PHOSPHATE; LITHIUM DERIVATIVE; MAGNESIUM;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; ENZYME SPECIFICITY; METABOLISM; QUANTUM THEORY;

BINDING SITES; INOSITOL PHOSPHATES; LITHIUM COMPOUNDS; MAGNESIUM; MODELS, MOLECULAR; QUANTUM THEORY; SUBSTRATE SPECIFICITY;

EID: 84866709839     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci300172r     Document Type: Article

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