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Volumn 30, Issue 10, 2012, Pages 2199-2211

A shRNA functional screen reveals Nme6 and Nme7 are crucial for embryonic stem cell renewal

Author keywords

Embryoid body; Embryonic stem cells; Pluripotency; Teratoma

Indexed keywords

DNA METHYLTRANSFERASE 3B; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; MYC PROTEIN; NUCLEOSIDE DIPHOSPHATE KINASE; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATASE; PROTEIN NME6; PROTEIN NME7; SHORT HAIRPIN RNA; TELOMERASE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 84866648827     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1203     Document Type: Article
Times cited : (26)

References (56)
  • 1
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell selfrenewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I et al. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell selfrenewal in collaboration with STAT3. Cell 2003;115:281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3
  • 2
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams RL, Hilton DJ, Pease S et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 1988;336:684-687.
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1    Hilton, D.J.2    Pease, S.3
  • 3
    • 30544450976 scopus 로고    scopus 로고
    • WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells
    • Hao J, Li TG, Qi X et al. WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells. Dev Biol 2006;290:81-91.
    • (2006) Dev Biol , vol.290 , pp. 81-91
    • Hao, J.1    Li, T.G.2    Qi, X.3
  • 4
    • 37349062460 scopus 로고    scopus 로고
    • Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3
    • Aksoy I, Sakabedoyan C, Bourillot PY et al. Self-renewal of murine embryonic stem cells is supported by the serine/threonine kinases Pim-1 and Pim-3. Stem Cells 2007;25:2996-3004.
    • (2007) Stem Cells , vol.25 , pp. 2996-3004
    • Aksoy, I.1    Sakabedoyan, C.2    Bourillot, P.Y.3
  • 5
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying QL, Wray J, Nichols J et al. The ground state of embryonic stem cell self-renewal. Nature 2008;453:519-523.
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.L.1    Wray, J.2    Nichols, J.3
  • 6
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X, Xu H, Yuan P et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008;133:1106-1117.
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3
  • 7
    • 34147117905 scopus 로고    scopus 로고
    • Zfx controls the selfrenewal of embryonic and hematopoietic stem cells
    • Galan-Caridad JM, Harel S, Arenzana TL et al. Zfx controls the selfrenewal of embryonic and hematopoietic stem cells. Cell 2007;129:345-357.
    • (2007) Cell , vol.129 , pp. 345-357
    • Galan-Caridad, J.M.1    Harel, S.2    Arenzana, T.L.3
  • 8
    • 1442311693 scopus 로고    scopus 로고
    • Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
    • Hay DC, Sutherland L, Clark J et al. Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 2004;22:225-235.
    • (2004) Stem Cells , vol.22 , pp. 225-235
    • Hay, D.C.1    Sutherland, L.2    Clark, J.3
  • 9
    • 25444435417 scopus 로고    scopus 로고
    • Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages
    • Hyslop L, Stojkovic M, Armstrong L et al. Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages. Stem Cells 2005;23:1035-1043.
    • (2005) Stem Cells , vol.23 , pp. 1035-1043
    • Hyslop, L.1    Stojkovic, M.2    Armstrong, L.3
  • 10
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I, Colby D, Robertson M et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003;113:643-655.
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3
  • 11
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K, Tokuzawa Y, Itoh H et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003;113:631-642.
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3
  • 12
    • 67849092746 scopus 로고    scopus 로고
    • The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming
    • Singh AM, Dalton S. The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell 2009;5:141-149.
    • (2009) Cell Stem Cell , vol.5 , pp. 141-149
    • Singh, A.M.1    Dalton, S.2
  • 13
    • 70549099970 scopus 로고    scopus 로고
    • The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics
    • Brooks TA, Hurley LH. The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics. Nat Rev Cancer 2009;9:849-861.
    • (2009) Nat Rev Cancer , vol.9 , pp. 849-861
    • Brooks, T.A.1    Hurley, L.H.2
  • 14
    • 0038100185 scopus 로고    scopus 로고
    • Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
    • Takahashi K, Mitsui K, Yamanaka S. Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature 2003;423:541-545.
    • (2003) Nature , vol.423 , pp. 541-545
    • Takahashi, K.1    Mitsui, K.2    Yamanaka, S.3
  • 15
    • 77957281337 scopus 로고    scopus 로고
    • Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer
    • Kubota E, Kataoka H, Aoyama M et al. Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer. Am J Pathol 2010;177:955-963.
    • (2010) Am J Pathol , vol.177 , pp. 955-963
    • Kubota, E.1    Kataoka, H.2    Aoyama, M.3
  • 16
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 17
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 18
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 20
    • 84856140580 scopus 로고    scopus 로고
    • Protein Phosphatases
    • 1st Edition. Berlin. German: Springer-Verlag
    • Arino J, Alexander DR. Protein Phosphatases. 1st Edition. Berlin. German: Springer-Verlag, Topics in Current Genetics, 2004;5:359.
    • (2004) Topics in Current Genetics , vol.5 , pp. 359
    • Arino, J.1    Alexander, D.R.2
  • 21
    • 28844506274 scopus 로고    scopus 로고
    • Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells
    • Takahashi K, Murakami M, Yamanaka S. Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells. Biochem Soc Trans 2005;33:1522-1525.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1522-1525
    • Takahashi, K.1    Murakami, M.2    Yamanaka, S.3
  • 22
    • 34247154612 scopus 로고    scopus 로고
    • Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
    • Storm MP, Bone HK, Beck CG et al. Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J Biol Chem 2007;282:6265-6273.
    • (2007) J Biol Chem , vol.282 , pp. 6265-6273
    • Storm, M.P.1    Bone, H.K.2    Beck, C.G.3
  • 23
    • 9144239955 scopus 로고    scopus 로고
    • Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
    • Paling NR, Wheadon H, Bone HK et al. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J Biol Chem 2004;279:48063-48070.
    • (2004) J Biol Chem , vol.279 , pp. 48063-48070
    • Paling, N.R.1    Wheadon, H.2    Bone, H.K.3
  • 24
    • 64349096829 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
    • Hu G, Kim J, Xu Q et al. A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev 2009;23:837-848.
    • (2009) Genes Dev , vol.23 , pp. 837-848
    • Hu, G.1    Kim, J.2    Xu, Q.3
  • 25
    • 65349123354 scopus 로고    scopus 로고
    • A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity
    • Ding L, Paszkowski-Rogacz M, Nitzsche A et al. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 2009;4:403-415.
    • (2009) Cell Stem Cell , vol.4 , pp. 403-415
    • Ding, L.1    Paszkowski-Rogacz, M.2    Nitzsche, A.3
  • 26
    • 77956387858 scopus 로고    scopus 로고
    • RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells
    • Coussens M, Davy P, Brown L et al. RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells. Proc Natl Acad Sci USA 2010;107:13842-13847.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13842-13847
    • Coussens, M.1    Davy, P.2    Brown, L.3
  • 28
    • 26644472432 scopus 로고    scopus 로고
    • An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit
    • Masui S, Shimosato D, Toyooka Y et al. An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res 2005;33:e43.
    • (2005) Nucleic Acids Res , vol.33
    • Masui, S.1    Shimosato, D.2    Toyooka, Y.3
  • 29
    • 38649094609 scopus 로고    scopus 로고
    • Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
    • Brambrink T, Foreman R, Welstead GG et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell 2008;2:151-159.
    • (2008) Cell Stem Cell , vol.2 , pp. 151-159
    • Brambrink, T.1    Foreman, R.2    Welstead, G.G.3
  • 30
    • 65349086683 scopus 로고    scopus 로고
    • A small molecule primes embryonic stem cells for differentiation
    • Zhu S, Wurdak H, Wang J et al. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell 2009;4:416-426.
    • (2009) Cell Stem Cell , vol.4 , pp. 416-426
    • Zhu, S.1    Wurdak, H.2    Wang, J.3
  • 31
    • 72449187617 scopus 로고    scopus 로고
    • Nme protein family evolutionary history, a vertebrate perspective
    • Desvignes T, Pontarotti P, Fauvel C et al. Nme protein family evolutionary history, a vertebrate perspective. BMC Evol Biol 2009;9:256.
    • (2009) BMC Evol Biol , vol.9 , pp. 256
    • Desvignes, T.1    Pontarotti, P.2    Fauvel, C.3
  • 32
    • 17144369093 scopus 로고    scopus 로고
    • Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer
    • Seifert M, Welter C, Mehraein Y et al. Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer. J Pathol 2005;205:623-632.
    • (2005) J Pathol , vol.205 , pp. 623-632
    • Seifert, M.1    Welter, C.2    Mehraein, Y.3
  • 33
    • 0033403353 scopus 로고    scopus 로고
    • A novel human nucleoside diphosphate (NDP) kinase, Nm23-H6, localizes in mitochondria and affects cytokinesis
    • Tsuiki H, Nitta M, Furuya A et al. A novel human nucleoside diphosphate (NDP) kinase, Nm23-H6, localizes in mitochondria and affects cytokinesis. J Cell Biochem 1999;76:254-269.
    • (1999) J Cell Biochem , vol.76 , pp. 254-269
    • Tsuiki, H.1    Nitta, M.2    Furuya, A.3
  • 35
    • 0033804737 scopus 로고    scopus 로고
    • The human Nm23/nucleoside diphosphate kinases
    • Lacombe ML, Milon L, Munier A et al. The human Nm23/nucleoside diphosphate kinases. J Bioenerg Biomembr 2000;32:247-258.
    • (2000) J Bioenerg Biomembr , vol.32 , pp. 247-258
    • Lacombe, M.L.1    Milon, L.2    Munier, A.3
  • 36
    • 79953814654 scopus 로고    scopus 로고
    • RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5
    • Zhu YX, Tiedemann R, Shi CX et al. RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5. Blood 2011;117:3847-3857.
    • (2011) Blood , vol.117 , pp. 3847-3857
    • Zhu, Y.X.1    Tiedemann, R.2    Shi, C.X.3
  • 37
    • 79953307660 scopus 로고    scopus 로고
    • Functional characterization of putative cilia genes by high-content analysis
    • Lai CK, Gupta N, Wen X et al. Functional characterization of putative cilia genes by high-content analysis. Mol Biol Cell 2011;22:1104-1119.
    • (2011) Mol Biol Cell , vol.22 , pp. 1104-1119
    • Lai, C.K.1    Gupta, N.2    Wen, X.3
  • 38
    • 78650115459 scopus 로고    scopus 로고
    • CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex
    • Choi YK, Liu P, Sze SK et al. CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. J Cell Biol 2010;191:1089-1095.
    • (2010) J Cell Biol , vol.191 , pp. 1089-1095
    • Choi, Y.K.1    Liu, P.2    Sze, S.K.3
  • 39
    • 77951819088 scopus 로고    scopus 로고
    • Systematic analysis of human protein complexes identifies chromosome segregation proteins
    • Hutchins JR, Toyoda Y, Hegemann B et al. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 2010;328:593-599.
    • (2010) Science , vol.328 , pp. 593-599
    • Hutchins, J.R.1    Toyoda, Y.2    Hegemann, B.3
  • 40
    • 72449197125 scopus 로고    scopus 로고
    • A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding
    • Gopalakrishnan S, Van Emburgh BO, Shan J et al. A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Mol Cancer Res 2009;7:1622-1634.
    • (2009) Mol Cancer Res , vol.7 , pp. 1622-1634
    • Gopalakrishnan, S.1    Van Emburgh, B.O.2    Shan, J.3
  • 41
    • 30144442965 scopus 로고    scopus 로고
    • KLF4, p21 and context-dependent opposing forces in cancer
    • Rowland BD, Peeper DS. KLF4, p21 and context-dependent opposing forces in cancer. Nat Rev Cancer 2006;6:11-23.
    • (2006) Nat Rev Cancer , vol.6 , pp. 11-23
    • Rowland, B.D.1    Peeper, D.S.2
  • 42
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem celllike gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ et al. An embryonic stem celllike gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008;40:499-507.
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3
  • 43
    • 34250315214 scopus 로고    scopus 로고
    • Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
    • Gu G, Yuan J, Wills M et al. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res 2007;67:4807-4815.
    • (2007) Cancer Res , vol.67 , pp. 4807-4815
    • Gu, G.1    Yuan, J.2    Wills, M.3
  • 44
    • 62449230721 scopus 로고    scopus 로고
    • Identification of cancer stem cells in Ewing's sarcoma
    • Suva ML, Riggi N, Stehle JC et al. Identification of cancer stem cells in Ewing's sarcoma. Cancer Res 2009;69:1776-1781.
    • (2009) Cancer Res , vol.69 , pp. 1776-1781
    • Suva, M.L.1    Riggi, N.2    Stehle, J.C.3
  • 45
    • 80053257189 scopus 로고    scopus 로고
    • CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Mullerian tumor)
    • Choijamts B, Jimi S, Kondo T et al. CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Mullerian tumor). Stem Cells 2011;29:1485-1495.
    • (2011) Stem Cells , vol.29 , pp. 1485-1495
    • Choijamts, B.1    Jimi, S.2    Kondo, T.3
  • 46
    • 78649522166 scopus 로고    scopus 로고
    • Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties
    • Leung EL, Fiscus RR, Tung JW et al. Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties. PLoS One 2010;5:e14062.
    • (2010) PLoS One , vol.5
    • Leung, E.L.1    Fiscus, R.R.2    Tung, J.W.3
  • 47
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 48
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park IH, Zhao R, West JA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008;451:141-146.
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 49
    • 0032911694 scopus 로고    scopus 로고
    • Direct activation of TERT transcription by c-MYC
    • Wu KJ, Grandori C, Amacker M et al. Direct activation of TERT transcription by c-MYC. Nat Genet 1999;21:220-224.
    • (1999) Nat Genet , vol.21 , pp. 220-224
    • Wu, K.J.1    Grandori, C.2    Amacker, M.3
  • 50
    • 84857022922 scopus 로고    scopus 로고
    • Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination
    • Deverman BE, Patterson PH. Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. J Neurosci 2012;32:2100-2109.
    • (2012) J Neurosci , vol.32 , pp. 2100-2109
    • Deverman, B.E.1    Patterson, P.H.2
  • 51
    • 80051869587 scopus 로고    scopus 로고
    • Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease
    • Cao W, Yang Y, Wang Z et al. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity 2011;35:273-284.
    • (2011) Immunity , vol.35 , pp. 273-284
    • Cao, W.1    Yang, Y.2    Wang, Z.3
  • 52
    • 80053467945 scopus 로고    scopus 로고
    • A WNTer revisit: New faces of beta-catenin and TCFs in pluripotency
    • Watanabe K, Dai X. A WNTer revisit: New faces of beta-catenin and TCFs in pluripotency. Sci Signal 2011;4:pe41.
    • (2011) Sci Signal , vol.4
    • Watanabe, K.1    Dai, X.2
  • 53
    • 84860370783 scopus 로고    scopus 로고
    • Trpc1 channel modulates PI3K/Akt pathway during myoblast differentiation and muscle regeneration
    • Zanou N, Schakman O, Louis P et al. Trpc1 channel modulates PI3K/Akt pathway during myoblast differentiation and muscle regeneration. J Biol Chem 2012;287:14524-14534.
    • (2012) J Biol Chem , vol.287 , pp. 14524-14534
    • Zanou, N.1    Schakman, O.2    Louis, P.3
  • 54
    • 80155137594 scopus 로고    scopus 로고
    • Master transcription factors determine cell-type-specific responses to TGF-2 Signaling
    • Mullen Alan C, Orlando David A, Newman Jamie J et al. Master transcription factors determine cell-type-specific responses to TGF-2 Signaling. Cell 2011;147:565-576.
    • (2011) Cell , vol.147 , pp. 565-576
    • Mullen Alan, C.1    Orlando David, A.2    Newman Jamie, J.3
  • 55
    • 3142707223 scopus 로고    scopus 로고
    • Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling
    • Fujita T, Azuma Y, Fukuyama R et al. Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling. J Cell Biol 2004;166:85-95.
    • (2004) J Cell Biol , vol.166 , pp. 85-95
    • Fujita, T.1    Azuma, Y.2    Fukuyama, R.3
  • 56
    • 33644747418 scopus 로고    scopus 로고
    • HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
    • Covello KL, Kehler J, Yu H et al. HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006;20:557-570.
    • (2006) Genes Dev , vol.20 , pp. 557-570
    • Covello, K.L.1    Kehler, J.2    Yu, H.3


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