Minimally invasive drug delivery to the cochlea through application of nanoparticles to the round window membrane

Nanomedicine

Volumn 7, Issue 9, 2012, Pages 1339-1354

  Buckiová, Daniela ^a   Ranjan, Sanjeev ^b   Newman, Tracey A ^c   Johnston, Alexander H ^c   Sood, Rohit ^b   Kinnunen, Paavo K J ^b   Popelář, Jiří ^a   Chumak, Tetyana ^a   Syka, Josef ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^b AALTO UNIVERSITY   (Finland)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

cell death; cochlea; disulfiram; hearing thresholds; liposome; mice; nanoparticles; polymersome; spiral ganglion

Indexed keywords

AMPHOPHILE; COPOLYMER; DISULFIRAM; LIPOSOME; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL STRUCTURE; COCHLEA FENESTRA; CONTROLLED STUDY; CORTI ORGAN; DRUG DELIVERY SYSTEM; EVOKED BRAIN STEM AUDITORY RESPONSE; HAIR CELL; HEARING IMPAIRMENT; MINIMALLY INVASIVE PROCEDURE; MOUSE; NONHUMAN; OTOACOUSTIC EMISSION; PRIORITY JOURNAL; SPIRAL GANGLION;

ANIMALS; APOPTOSIS; CASPASE 3; COCHLEA; CYTOTOXINS; DISULFIRAM; DRUG DELIVERY SYSTEMS; FEMALE; LIPOSOMES; MALE; MICE; NANOPARTICLES; ORGAN OF CORTI; ROUND WINDOW, EAR; SPIRAL GANGLION; SURFACE-ACTIVE AGENTS;

EID: 84866636932     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.5     Document Type: Article

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