-
1
-
-
81855169964
-
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
-
Kang T-W, et al. (2011) Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature 479:547-551.
-
(2011)
Nature
, vol.479
, pp. 547-551
-
-
Kang, T.-W.1
-
2
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
DOI 10.1038/nature06309, PII NATURE06309
-
Koebel CM, et al. (2007) Adaptive immunity maintains occult cancer in an equilibrium state. Nature 450:903-907. (Pubitemid 350231320)
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
Zerafa, N.4
Rodig, S.J.5
Old, L.J.6
Smyth, M.J.7
Schreiber, R.D.8
-
3
-
-
0036852191
-
Natural selection of tumor variants in the generation of "tumor escape" phenotypes
-
DOI 10.1038/ni1102-999
-
Khong HT, Restifo NP (2002) Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat Immunol 3:999-1005. (Pubitemid 35363649)
-
(2002)
Nature Immunology
, vol.3
, Issue.11
, pp. 999-1005
-
-
Khong, H.T.1
Restifo, N.P.2
-
5
-
-
0023782359
-
The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes
-
Chiu R, et al. (1988) The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54:541-552.
-
(1988)
Cell
, vol.54
, pp. 541-552
-
-
Chiu, R.1
-
6
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
DOI 10.1038/ncb0502-e131
-
Shaulian E, Karin M (2002) AP-1 as a regulator of cell life and death. Nat Cell Biol 4: E131-E136. (Pubitemid 34521026)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.5
-
-
Shaulian, E.1
Karin, M.2
-
7
-
-
79955738613
-
A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summation
-
Clark CE, Hasan M, Bousso P (2011) A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summation. PLoS ONE 6:e18916.
-
(2011)
PLoS ONE
, vol.6
-
-
Clark, C.E.1
Hasan, M.2
Bousso, P.3
-
8
-
-
0025255387
-
Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: The missing link
-
Ullman KS, Northrop JP, Verweij CL, Crabtree GR (1990) Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: The missing link. Annu Rev Immunol 8:421-452. (Pubitemid 20135634)
-
(1990)
Annual Review of Immunology
, vol.8
, pp. 421-452
-
-
Ullman, K.S.1
Northrop, J.P.2
Verweij, C.L.3
Crabtree, G.R.4
-
9
-
-
0035971436
-
Partners in transcription: NFAT and AP-1
-
DOI 10.1038/sj.onc.1204386
-
Macián F, López-Rodríguez C, Rao A (2001) Partners in transcription: NFAT and AP-1. Oncogene 20:2476-2489. (Pubitemid 32531304)
-
(2001)
Oncogene
, vol.20
, Issue.19 REV. ISS. 2
, pp. 2476-2489
-
-
Macian, F.1
Lopez-Rodriguez, C.2
Rao, A.3
-
10
-
-
67650422616
-
The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression
-
Ilkovitch D, Lopez DM (2009) The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression. Cancer Res 69:5514-5521.
-
(2009)
Cancer Res
, vol.69
, pp. 5514-5521
-
-
Ilkovitch, D.1
Lopez, D.M.2
-
11
-
-
10544232277
-
Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape
-
DOI 10.1126/science.274.5291.1363
-
Hahne M, et al. (1996) Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape. Science 274:1363-1366. (Pubitemid 26391458)
-
(1996)
Science
, vol.274
, Issue.5291
, pp. 1363-1366
-
-
Hahne, M.1
Rimoldi, D.2
Schroter, M.3
Romero, P.4
Schreier, M.5
French, L.E.6
Schneider, P.7
Bornand, T.8
Fontana, A.9
Lienard, D.10
Cerottini, J.-C.11
Tschopp, J.12
-
12
-
-
0141988724
-
Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-fos in the CNS
-
Fleischmann A, et al. (2003) Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS. J Neurosci 23: 9116-9122. (Pubitemid 37243812)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.27
, pp. 9116-9122
-
-
Fleischmann, A.1
Hvalby, O.2
Jensen, V.3
Strekalova, T.4
Zacher, C.5
Layer, L.E.6
Kvello, A.7
Reschke, M.8
Spanagel, R.9
Sprengel, R.10
Wagner, E.F.11
Gass, P.12
-
13
-
-
0347717903
-
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
-
DOI 10.1038/nature02238
-
Mempel TR, Henrickson SE, Von Andrian UH (2004) T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427:154-159. (Pubitemid 38094955)
-
(2004)
Nature
, vol.427
, Issue.6970
, pp. 154-159
-
-
Mempel, T.R.1
Henrickson, S.E.2
Von Andrian, U.H.3
-
14
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N, et al. (2009) T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 31:787-798.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
-
15
-
-
61849171872
-
C-Fos enhances the survival of thymocytes during positive selection by upregulating Bcl-2
-
Wang X, Zhang Y, Xiao G, Gao X, Liu X (2009) c-Fos enhances the survival of thymocytes during positive selection by upregulating Bcl-2. Cell Res 19:340-347.
-
(2009)
Cell Res
, vol.19
, pp. 340-347
-
-
Wang, X.1
Zhang, Y.2
Xiao, G.3
Gao, X.4
Liu, X.5
-
16
-
-
24344436369
-
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
-
DOI 10.1038/nature03954, PII N03954
-
Willimsky G, Blankenstein T (2005) Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature 437:141-146. (Pubitemid 41613441)
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 141-146
-
-
Willimsky, G.1
Blankenstein, T.2
-
17
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
Ahmadzadeh M, et al. (2009) Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 114:1537-1544.
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
-
18
-
-
58149314579
-
NFATc1 regulates PD-1 expression upon T cell activation
-
Oestreich KJ, Yoon H, Ahmed R, Boss JM (2008) NFATc1 regulates PD-1 expression upon T cell activation. J Immunol 181:4832-4839.
-
(2008)
J Immunol
, vol.181
, pp. 4832-4839
-
-
Oestreich, K.J.1
Yoon, H.2
Ahmed, R.3
Boss, J.M.4
-
19
-
-
79952767536
-
IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity
-
Terawaki S, et al. (2011) IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. J Immunol 186: 2772-2779.
-
(2011)
J Immunol
, vol.186
, pp. 2772-2779
-
-
Terawaki, S.1
-
20
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
DOI 10.1038/nm1093
-
Curiel TJ, et al. (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10:942-949. (Pubitemid 39273735)
-
(2004)
Nature Medicine
, vol.10
, Issue.9
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
Zhu, Y.11
Wei, S.12
Kryczek, I.13
Daniel, B.14
Gordon, A.15
Myers, L.16
Lackner, A.17
Disis, M.L.18
Knutson, K.L.19
Chen, L.20
Zou, W.21
more..
-
21
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
-
Guy CT, Cardiff RD, Muller WJ (1992) Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease. Mol Cell Biol 12:954-961.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
22
-
-
33646855417
-
c-Fos suppresses systemic inflammatory response to endotoxin
-
DOI 10.1093/intimm/dxl004
-
Ray N, et al. (2006) c-Fos suppresses systemic inflammatory response to endotoxin. Int Immunol 18:671-677. (Pubitemid 43779057)
-
(2006)
International Immunology
, vol.18
, Issue.5
, pp. 671-677
-
-
Ray, N.1
Kuwahara, M.2
Takada, Y.3
Maruyama, K.4
Kawaguchi, T.5
Tsubone, H.6
Ishikawa, H.7
Matsuo, K.8
-
23
-
-
62049085056
-
Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein
-
Koga K, et al. (2009) Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein. Immunity 30: 372-383.
-
(2009)
Immunity
, vol.30
, pp. 372-383
-
-
Koga, K.1
-
24
-
-
0029860936
-
Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
-
DOI 10.1126/science.274.5290.1194
-
Rosette C, Karin M (1996) Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274: 1194-1197. (Pubitemid 26389285)
-
(1996)
Science
, vol.274
, Issue.5290
, pp. 1194-1197
-
-
Rosette, C.1
Karin, M.2
-
25
-
-
82755192227
-
Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration
-
Schaeuble K, Hauser MA, Singer E, Groettrup M, Legler DF (2011) Cross-talk between TCR and CCR7 signaling sets a temporal threshold for enhanced T lymphocyte migration. J Immunol 187:5645-5652.
-
(2011)
J Immunol
, vol.187
, pp. 5645-5652
-
-
Schaeuble, K.1
Hauser, M.A.2
Singer, E.3
Groettrup, M.4
Legler, D.F.5
-
27
-
-
10744220884
-
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice
-
DOI 10.1038/nm955
-
Okazaki T, et al. (2003) Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. Nat Med 9:1477-1483. (Pubitemid 38004774)
-
(2003)
Nature Medicine
, vol.9
, Issue.12
, pp. 1477-1483
-
-
Okazaki, T.1
Tanaka, Y.2
Nishio, R.3
Mitsuiye, T.4
Mizoguchi, A.5
Wang, J.6
Ishida, M.7
Hiai, H.8
Matsumori, A.9
Minato, N.10
Honjo, T.11
-
28
-
-
13244277850
-
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
-
DOI 10.1038/ng1020
-
Prokunina L, et al. (2002) A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 32:666-669. (Pubitemid 35435182)
-
(2002)
Nature Genetics
, vol.32
, Issue.4
, pp. 666-669
-
-
Prokunina, L.1
Castillejo-Lopez, C.2
Oberg, F.3
Gunnarsson, I.4
Berg, L.5
Magnusson, V.6
Brookes, A.J.7
Tentler, D.8
Kristjansdottir, H.9
Grondal, G.10
Isine, B.A.11
Svenungsson, E.12
Lundberg, I.13
Sturfelt, G.14
Jonssen, A.15
Truedsson, L.16
Lima, G.17
Alcocer-Varela, J.18
Jonsson, R.19
Gyllensten, U.B.20
Harley, J.B.21
Alarcon-Segovia, D.22
Steinsson, K.23
Alarcon-Riquelme, M.E.24
more..
-
29
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
DOI 10.1038/nature05115, PII NATURE05115
-
Day CL, et al. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350-354. (Pubitemid 44435155)
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.R.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
30
-
-
36148946411
-
+ T cells in Hodgkin lymphoma
-
DOI 10.1182/blood-2006-12-064360
-
Chemnitz JM, et al. (2007) RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood 110:3226-3233. (Pubitemid 350106315)
-
(2007)
Blood
, vol.110
, Issue.9
, pp. 3226-3233
-
-
Chemnitz, J.M.1
Eggle, D.2
Driesen, J.3
Classen, S.4
Riley, J.L.5
Debey-Pascher, S.6
Beyer, M.7
Popov, A.8
Zander, T.9
Schultze, J.L.10
-
31
-
-
33846465547
-
Immunostimulatory monoclonal antibodies for cancer therapy
-
DOI 10.1038/nrc2051, PII NRC2051
-
Melero I, Hervas-Stubbs S, Glennie M, Pardoll DM, Chen L (2007) Immunostimulatory monoclonal antibodies for cancer therapy. Nat Rev Cancer 7:95-106. (Pubitemid 46160986)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.2
, pp. 95-106
-
-
Melero, I.1
Hervas-Stubbs, S.2
Glennie, M.3
Pardoll, D.M.4
Chen, L.5
-
32
-
-
79959375167
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
-
Kao C, et al. (2011) Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection. Nat Immunol 12:663-671.
-
(2011)
Nat Immunol
, vol.12
, pp. 663-671
-
-
Kao, C.1
-
33
-
-
34347389213
-
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells
-
DOI 10.1182/blood-2006-12-062422
-
Goldberg MV, et al. (2007) Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood 110:186-192. (Pubitemid 47026834)
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 186-192
-
-
Goldberg, M.V.1
Maris, C.H.2
Hipkiss, E.L.3
Flies, A.S.4
Zhen, L.5
Tuder, R.M.6
Grosso, J.F.7
Harris, T.J.8
Getnet, D.9
Whartenby, K.A.10
Brockstedt, D.G.11
Dubensky Jr., T.W.12
Chen, L.13
Pardoll, D.M.14
Drake, C.G.15
-
34
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco LM, et al. (2009) PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med 206:3015-3029.
-
(2009)
J Exp Med
, vol.206
, pp. 3015-3029
-
-
Francisco, L.M.1
-
35
-
-
0035158734
-
Hyper immunoglobulin e response in mice with monoclonal populations of B and T lymphocytes
-
Curotto de Lafaille MA, et al. (2001) Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes. J Exp Med 194:1349-1359.
-
(2001)
J Exp Med
, vol.194
, pp. 1349-1359
-
-
Curotto De Lafaille, M.A.1
|