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Volumn 100, Issue 1, 2009, Pages 111-116

Nek2 as a novel molecular target for the treatment of breast carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PROTEIN KINASE NEK2; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 58149284063     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.01007.x     Document Type: Article
Times cited : (94)

References (22)
  • 1
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • Baselga J, Norton L, Albanell J, Kim YM, Mendelsohn J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 1998; 58: 2825-31.
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3    Kim, Y.M.4    Mendelsohn, J.5
  • 3
    • 33847136743 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Therapeutic options
    • Cleator S, Heller W, Coombes RC. Triple-negative breast cancer: therapeutic options. Lancet Oncol 2007; 8: 235-44.
    • (2007) Lancet Oncol , vol.8 , pp. 235-244
    • Cleator, S.1    Heller, W.2    Coombes, R.C.3
  • 4
    • 0032518798 scopus 로고    scopus 로고
    • A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
    • Fry AM, Meraldi P, Nigg EA. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J 1998; 17: 470-81.
    • (1998) EMBO J , vol.17 , pp. 470-481
    • Fry, A.M.1    Meraldi, P.2    Nigg, E.A.3
  • 5
    • 0037048312 scopus 로고    scopus 로고
    • The Nek2 protein kinase: A novel regulator of centrosome structure
    • Fry AM. The Nek2 protein kinase: A novel regulator of centrosome structure. Oncogene 2002; 21: 6184-94.
    • (2002) Oncogene , vol.21 , pp. 6184-6194
    • Fry, A.M.1
  • 7
    • 35448935555 scopus 로고    scopus 로고
    • Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma
    • Kokuryo T, Senga T, Yokoyama Y, Nagino M, Nimura Y, Hamaguchi M. Nek2 as an effective target for inhibition of tumorigenic growth and peritoneal dissemination of cholangiocarcinoma. Cancer Res 2007; 67: 9637-42.
    • (2007) Cancer Res , vol.67 , pp. 9637-9642
    • Kokuryo, T.1    Senga, T.2    Yokoyama, Y.3    Nagino, M.4    Nimura, Y.5    Hamaguchi, M.6
  • 8
    • 5644280152 scopus 로고    scopus 로고
    • The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer
    • Hayward DG, Clarke RB, Faragher AJ, Pillai MR, Hagan IM, Fry AM. The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer. Cancer Res 2004; 64: 7370-6.
    • (2004) Cancer Res , vol.64 , pp. 7370-7376
    • Hayward, D.G.1    Clarke, R.B.2    Faragher, A.J.3    Pillai, M.R.4    Hagan, I.M.5    Fry, A.M.6
  • 9
    • 0037324949 scopus 로고    scopus 로고
    • Gene expression profile of serial samples of transformed B-cell lymphomas
    • de Vos S, Hofmann WK, Grogan TM et al. Gene expression profile of serial samples of transformed B-cell lymphomas. Lab Invest 2003; 83: 271-85.
    • (2003) Lab Invest , vol.83 , pp. 271-285
    • de Vos, S.1    Hofmann, W.K.2    Grogan, T.M.3
  • 10
    • 0027459346 scopus 로고
    • p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system
    • Hamaguchi M, Matsuyoshi N, Ohnishi Y, Gotoh B, Takeichi M, Nagai Y. p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. Embo J 1993; 12: 307-14.
    • (1993) Embo J , vol.12 , pp. 307-314
    • Hamaguchi, M.1    Matsuyoshi, N.2    Ohnishi, Y.3    Gotoh, B.4    Takeichi, M.5    Nagai, Y.6
  • 11
    • 13944271340 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2
    • Tanimura Y, Kokuryo T, Tsunoda N et al. Tumor necrosis factor alpha promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2. Cancer Lett 2005; 219: 205-13.
    • (2005) Cancer Lett , vol.219 , pp. 205-213
    • Tanimura, Y.1    Kokuryo, T.2    Tsunoda, N.3
  • 12
    • 33746122371 scopus 로고    scopus 로고
    • A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1
    • Mon NN, Hasegawa H, Thant AA et al. A role for focal adhesion kinase signaling in tumor necrosis factor-alpha-dependent matrix metalloproteinase-9 production in a cholangiocarcinoma cell line, CCKS1. Cancer Res 2006; 66: 6778-84.
    • (2006) Cancer Res , vol.66 , pp. 6778-6784
    • Mon, N.N.1    Hasegawa, H.2    Thant, A.A.3
  • 13
    • 46949111665 scopus 로고    scopus 로고
    • Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival
    • Toi M, Nakamura S, Kuroi K et al. Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival. Breast Cancer Res Treat 2008; 110 (3): 531-9.
    • (2008) Breast Cancer Res Treat , vol.110 , Issue.3 , pp. 531-539
    • Toi, M.1    Nakamura, S.2    Kuroi, K.3
  • 14
    • 4444254432 scopus 로고    scopus 로고
    • Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer
    • Esslimani-Sahla M, Simony-Lafontaine J, Kramar A et al. Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer. Clin Cancer Res 2004; 10: 5769-76.
    • (2004) Clin Cancer Res , vol.10 , pp. 5769-5776
    • Esslimani-Sahla, M.1    Simony-Lafontaine, J.2    Kramar, A.3
  • 15
    • 12244252332 scopus 로고    scopus 로고
    • Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
    • Aas T, Geisler S, Eide GE et al. Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy. Eur J Cancer 2003; 39: 438-46.
    • (2003) Eur J Cancer , vol.39 , pp. 438-446
    • Aas, T.1    Geisler, S.2    Eide, G.E.3
  • 16
    • 34547836352 scopus 로고    scopus 로고
    • Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracycline-based chemotherapy: A biomarker study from two randomized trials
    • Conforti R, Boulet T, Tomasic G et al. Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracycline-based chemotherapy: A biomarker study from two randomized trials. Ann Oncol 2007; 18: 1477-83.
    • (2007) Ann Oncol , vol.18 , pp. 1477-1483
    • Conforti, R.1    Boulet, T.2    Tomasic, G.3
  • 17
    • 1042292612 scopus 로고    scopus 로고
    • Advances in estrogen receptor biology: Prospects for improvements in targeted breast cancer therapy
    • Shao W, Brown M. Advances in estrogen receptor biology: Prospects for improvements in targeted breast cancer therapy. Breast Cancer Res 2004; 6: 39-52.
    • (2004) Breast Cancer Res , vol.6 , pp. 39-52
    • Shao, W.1    Brown, M.2
  • 18
    • 3042540199 scopus 로고    scopus 로고
    • Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes
    • Yoshida N, Omoto Y, Inoue A et al. Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes. Cancer Sci 2004; 95: 496-502.
    • (2004) Cancer Sci , vol.95 , pp. 496-502
    • Yoshida, N.1    Omoto, Y.2    Inoue, A.3
  • 19
    • 0037025173 scopus 로고    scopus 로고
    • Cancer: Addiction to Oncogenes - The Achilles heal of cancer
    • Weinstein IB. Cancer: Addiction to Oncogenes - the Achilles heal of cancer. Science 2002; 297 (5578): 63-4.
    • (2002) Science , vol.297 , Issue.5578 , pp. 63-64
    • Weinstein, I.B.1
  • 20
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • Moody SE, Perez D, Pan TC et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 2005; 8: 197-209.
    • (2005) Cancer Cell , vol.8 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3
  • 21
    • 0035126052 scopus 로고    scopus 로고
    • c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • D'Cruz CM, Gunther EJ, Boxer RB et al. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med 2001; 7: 235-9.
    • (2001) Nat Med , vol.7 , pp. 235-239
    • D'Cruz, C.M.1    Gunther, E.J.2    Boxer, R.B.3
  • 22
    • 0037442760 scopus 로고    scopus 로고
    • Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
    • Gunther EJ, Moody SE, Belka GK et al. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev 2003; 17: 488-501.
    • (2003) Genes Dev , vol.17 , pp. 488-501
    • Gunther, E.J.1    Moody, S.E.2    Belka, G.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.