Development of novel microprecipitated bulk powder (MBP) technology for manufacturing stable amorphous formulations of poorly soluble drugs

International Journal of Pharmaceutics

Volumn 438, Issue 1-2, 2012, Pages 53-60

  Shah, Navnit ^a   Sandhu, Harpreet ^a   Phuapradit, Wantanee ^b   Pinal, Rodolfo ^c   Iyer, Raman ^a   Albano, Antonio ^a   Chatterji, Ashish ^a   Anand, Shalini ^a   Choi, Duk Soon ^a   Tang, Kin ^a   Tian, Hung ^a   Chokshi, Hitesh ^a   Singhal, Dharmendra ^a   Malick, Waseem ^a  

^a Pharmaceutical and Analytical R and D   (United States)

^b Kashiv Pharma   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

Amorphous; Co precipitation; MBP; Solid dispersion; Solid solution

Indexed keywords

EUDRAGIT; EUDRAGIT L100; EUDRAGIT L100-5; HYDROXYPROPYLMETHYLCELLULOSE; HYPROMELLOSE ACETATE SUCCINATE; HYPROMELLOSE PHTHALATE 50; KLUCEL LF; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N,N DIMETHYLACETAMIDE; POLOXAMER; POLYMER; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; DISPERSION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; MICROPRECIPITATED BULK POWDER; POWDER; PRECIPITATION; PRIORITY JOURNAL;

ACETAMIDES; ANIMALS; ANTINEOPLASTIC AGENTS; DOGS; DRUG COMPOUNDING; PHARMACEUTICAL PREPARATIONS; POLYMERS; POWDERS; RATS; SOLUBILITY;

EID: 84866496949     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.08.031     Document Type: Article

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