Mitochondrial ATP-sensitive potassium channels enhance angiotensin-induced oxidative damage and dopaminergic neuron degeneration. Relevance for aging-associated susceptibility to Parkinson's disease

Age

Volumn 34, Issue 4, 2012, Pages 863-880

  Rodriguez Pallares, Jannette ^a,b   Parga, Juan Andres ^a,b   Joglar, Belen ^a,b   Guerra, Maria Jose ^a,b   Labandeira Garcia, Jose Luis ^a,b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Aging; Neurodegeneration; Neuroinflammation; Oxidative stress; Parkinson's disease; Renin angiotensin system

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ANGIOTENSIN II; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AGING; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; DOPAMINERGIC NERVE CELL; EMBRYO; ENZYME ACTIVITY; IMMUNOCYTOCHEMISTRY; MESENCEPHALON; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK ASSESSMENT; RISK FACTOR;

AGING; ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; DOPAMINERGIC NEURONS; FLUORESCENCE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; OXIDATIVE STRESS; OXIDOPAMINE; PARKINSON DISEASE; POTASSIUM CHANNELS; RATS; REACTIVE OXYGEN SPECIES; REFERENCE VALUES; RENIN-ANGIOTENSIN SYSTEM; SENSITIVITY AND SPECIFICITY; SUBSTANTIA NIGRA;

EID: 84866492850     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9284-7     Document Type: Article

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