Angiotensin II type 1A receptor deficiency and longevity

Nephrology Dialysis Transplantation

Volumn 24, Issue 11, 2009, Pages 3280-3281

  Nishiyama, Akira ^a   Matsusaka, Taiji ^b   Miyata, Toshio ^c  

^a KAGAWA UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II (AngII); AT1A receptor; Longevity; Mitochondria; Oxidative stress

Indexed keywords

ANGIOTENSIN 1A RECEPTOR; ANGIOTENSIN 1B RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SIRTUIN 3; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST;

AGING; ANGIOTENSIN 1A RECEPTOR DEFICIENCY; GENE MUTATION; HETEROZYGOTE; KIDNEY HYPERTROPHY; KIDNEY INJURY; LONGEVITY; MEDICAL RESEARCH; NONHUMAN; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RENAL PROTECTION; TERATOGENESIS; UPREGULATION; ANIMAL; ARTICLE; DRUG EFFECT; METABOLISM; MITOCHONDRION; MOUSE; PHYSIOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; LONGEVITY; MICE; MITOCHONDRIA; OXIDATIVE STRESS; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM;

EID: 73949100355     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp381     Document Type: Note

References (12)

1. Benigni A, Corna D, Zoja C, et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 2009; 119: 524-530
2. Schmieder RE, Hilgers KF, Schlaich MP, et al. Renin-angiotensin system and cardiovascular risk. Lancet 2007; 369: 1208-1219
3. Shotan A, Widerhorn J, Hurst A, et al. Risks of angiotensin-converting enzyme inhibition during pregnancy: experimental and clinical evidence, potential mechanisms, and recommendations for use. Am J Med 1994; 96: 451-456
4. Kim HS, Krege JH, Kluckman KD, et al. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci USA 1995; 92: 2735-2739
5. Krege JH, John SW, Langenbach LL, et al. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature 1995; 375: 146-148
6. Oliverio MI, Kim HS, Ito M, et al. Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. Proc Natl Acad Sci USA 1998; 95: 15496-15501
7. Schmitt R, Jacobi C, Susnik N, et al. Ageing mouse kidney-not always the SAME old story. Nephrol Dial Transplant 2009; 24: 3002-3005
8. Hitomi H, Kiyomoto H, Nishiyama A. Angiotensin II and oxidative stress. Curr Opin Cardiol 2007; 22: 311-315
9. Kobori H, Nangaku M, Navar LG, et al. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 2007; 59: 251-287
10. Aragones J, Schneider M, Van Geyte K, et al. Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet 2008; 40: 170-180
11. Izuhara Y, Nangaku M, Inagi R, et al. Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering. J Am Soc Nephrol 2005; 16: 3631-3641
12. Miyata T, van Ypersele de Strihou C. Translation of basic science into clinical medicine: novel targets for diabetic nephropathy. Nephrol Dial Transplant 2009; 24: 1373-1377