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Volumn 223, Issue , 2012, Pages 296-304

Maternal separation and proclivity for ethanol intake: A potential role of the endocannabinoid system in rats

Author keywords

Alcohol consumption; CB1 receptor; Endocannabinoid system; Epigenetics; Maternal separation

Indexed keywords

4 AMINOBUTYRIC ACID; ALCOHOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; GLUCOCORTICOID RECEPTOR; GLUTAMIC ACID; METHYL CPG BINDING PROTEIN 2; TAP WATER;

EID: 84866483096     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.07.071     Document Type: Article
Times cited : (40)

References (56)
  • 1
    • 45849131649 scopus 로고    scopus 로고
    • Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats
    • Aisa B., Tordera R., Lasheras B., Del Rio J., Ramirez M.J. Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats. Neuroscience 2008, 154:1218-1226.
    • (2008) Neuroscience , vol.154 , pp. 1218-1226
    • Aisa, B.1    Tordera, R.2    Lasheras, B.3    Del Rio, J.4    Ramirez, M.J.5
  • 2
    • 82955187642 scopus 로고    scopus 로고
    • Effects of stress on alcohol drinking: a review of animal studies
    • Becker H.C., Lopez M.F., Doremus-Fitzwater T.L. Effects of stress on alcohol drinking: a review of animal studies. Psychopharmacology 2011, 218:131-156.
    • (2011) Psychopharmacology , vol.218 , pp. 131-156
    • Becker, H.C.1    Lopez, M.F.2    Doremus-Fitzwater, T.L.3
  • 3
    • 0032574859 scopus 로고    scopus 로고
    • Methylation meets acetylation
    • Bestor T.H. Methylation meets acetylation. Nature 1998, 393:311-312.
    • (1998) Nature , vol.393 , pp. 311-312
    • Bestor, T.H.1
  • 5
    • 0034672322 scopus 로고    scopus 로고
    • Variations in maternal care in infancy regulate the development of stress reactivity
    • Caldji C., Diorio J., Meaney M.J. Variations in maternal care in infancy regulate the development of stress reactivity. Biol Psychol 2000, 48:1164-1174.
    • (2000) Biol Psychol , vol.48 , pp. 1164-1174
    • Caldji, C.1    Diorio, J.2    Meaney, M.J.3
  • 6
    • 0242472819 scopus 로고    scopus 로고
    • Variations in maternal care alter GABA(A) receptor subunit expression in brain regions associated with fear
    • Caldji C., Diorio J., Meaney M.J. Variations in maternal care alter GABA(A) receptor subunit expression in brain regions associated with fear. Neuropsychopharmacology 2003, 28:1950-1959.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1950-1959
    • Caldji, C.1    Diorio, J.2    Meaney, M.J.3
  • 7
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M., Jung S.Y., Shaw C., Zhou X., Wong S.T., Qin J., Zoghbi H.Y. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008, 320:1224-1229.
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6    Zoghbi, H.Y.7
  • 8
    • 56549119022 scopus 로고    scopus 로고
    • Maternal separation stress in male mice: long-term increases in alcohol intake
    • Cruz F.C., Quadros I.M., Planeta Cda S., Miczek K.A. Maternal separation stress in male mice: long-term increases in alcohol intake. Psychopharmacology 2008, 201:459-468.
    • (2008) Psychopharmacology , vol.201 , pp. 459-468
    • Cruz, F.C.1    Quadros, I.M.2    Planeta Cda, S.3    Miczek, K.A.4
  • 10
    • 50049101718 scopus 로고    scopus 로고
    • The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats
    • Dyr W., Ligieza J., Kostowski W. The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats. Alcohol 2008, 42:509-512.
    • (2008) Alcohol , vol.42 , pp. 509-512
    • Dyr, W.1    Ligieza, J.2    Kostowski, W.3
  • 11
    • 84860610609 scopus 로고    scopus 로고
    • The influence of gene-environment interactions on the development of alcoholism and drug dependence
    • Enoch M.A. The influence of gene-environment interactions on the development of alcoholism and drug dependence. Curr Psychiatry Rep 2012, 14:150-158.
    • (2012) Curr Psychiatry Rep , vol.14 , pp. 150-158
    • Enoch, M.A.1
  • 12
    • 0001550944 scopus 로고    scopus 로고
    • The genetics of alcoholism and alcohol abuse
    • Enoch M.A., Goldman D. The genetics of alcoholism and alcohol abuse. Curr Psychiatry Rep 2001, 3:144-151.
    • (2001) Curr Psychiatry Rep , vol.3 , pp. 144-151
    • Enoch, M.A.1    Goldman, D.2
  • 13
    • 33847165373 scopus 로고    scopus 로고
    • Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats
    • Fullgrabe M.W., Vengeliene V., Spanagel R. Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats. Pharmacol Biochem Behav 2007, 86:320-326.
    • (2007) Pharmacol Biochem Behav , vol.86 , pp. 320-326
    • Fullgrabe, M.W.1    Vengeliene, V.2    Spanagel, R.3
  • 14
    • 12544253479 scopus 로고    scopus 로고
    • Suppressing effect of the cannabinoid CB1 receptor antagonist, SR147778, on alcohol intake and motivational properties of alcohol in alcohol-preferring sP rats
    • Gessa G.L., Serra S., Vacca G., Carai M.A., Colombo G. Suppressing effect of the cannabinoid CB1 receptor antagonist, SR147778, on alcohol intake and motivational properties of alcohol in alcohol-preferring sP rats. Alcohol Alcohol 2005, 40:46-53.
    • (2005) Alcohol Alcohol , vol.40 , pp. 46-53
    • Gessa, G.L.1    Serra, S.2    Vacca, G.3    Carai, M.A.4    Colombo, G.5
  • 15
    • 0037716607 scopus 로고    scopus 로고
    • Early experience and depressive disorders: human and non-human primate studies
    • Gilmer W.S., McKinney W.T. Early experience and depressive disorders: human and non-human primate studies. J Affect Disord 2003, 75:97-113.
    • (2003) J Affect Disord , vol.75 , pp. 97-113
    • Gilmer, W.S.1    McKinney, W.T.2
  • 16
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: uncovering the genes
    • Goldman D., Oroszi G., Ducci F. The genetics of addictions: uncovering the genes. Nature Rev Genet 2005, 6:521-532.
    • (2005) Nature Rev Genet , vol.6 , pp. 521-532
    • Goldman, D.1    Oroszi, G.2    Ducci, F.3
  • 17
    • 0035186226 scopus 로고    scopus 로고
    • Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens. A comparison with opioids
    • Hofmann A.F., Lupica C.R. Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens. A comparison with opioids. J Neurophysiol 2001, 85:72-83.
    • (2001) J Neurophysiol , vol.85 , pp. 72-83
    • Hofmann, A.F.1    Lupica, C.R.2
  • 18
    • 12344282798 scopus 로고    scopus 로고
    • CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors
    • Houchi H., Babovic D., Pierrefiche O., Ledent C., Daoust M., Naassila M. CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology 2005, 30:339-349.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 339-349
    • Houchi, H.1    Babovic, D.2    Pierrefiche, O.3    Ledent, C.4    Daoust, M.5    Naassila, M.6
  • 19
    • 0037317155 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens
    • Hungund B.L., Szakall I., Adam A., Basavarajappa B.S., Vadasz C. Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens. J Neurochem 2003, 84:698-704.
    • (2003) J Neurochem , vol.84 , pp. 698-704
    • Hungund, B.L.1    Szakall, I.2    Adam, A.3    Basavarajappa, B.S.4    Vadasz, C.5
  • 20
    • 0035207885 scopus 로고    scopus 로고
    • Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats reversal with antidepressant treatment
    • Huot R.L., Thrivikraman K.V., Meaney M.J., Plotsky P.M. Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats reversal with antidepressant treatment. Psychopharmacology 2001, 158:366-373.
    • (2001) Psychopharmacology , vol.158 , pp. 366-373
    • Huot, R.L.1    Thrivikraman, K.V.2    Meaney, M.J.3    Plotsky, P.M.4
  • 22
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • Kalivas P.W. The glutamate homeostasis hypothesis of addiction. Nature Rev Neurosci 2009, 10:561-572.
    • (2009) Nature Rev Neurosci , vol.10 , pp. 561-572
    • Kalivas, P.W.1
  • 23
    • 0014202402 scopus 로고
    • Maternal and environmental influences on the adrenocortical response to stress in weanling rats
    • Levine S. Maternal and environmental influences on the adrenocortical response to stress in weanling rats. Science 1967, 156:258-260.
    • (1967) Science , vol.156 , pp. 258-260
    • Levine, S.1
  • 24
    • 0034948783 scopus 로고    scopus 로고
    • Primary social relationships influence the development of the hypothalamic-pituitary-adrenal axis in the rat
    • Levine S. Primary social relationships influence the development of the hypothalamic-pituitary-adrenal axis in the rat. Physiol Behav 2001, 73:255-260.
    • (2001) Physiol Behav , vol.73 , pp. 255-260
    • Levine, S.1
  • 25
    • 22144473378 scopus 로고    scopus 로고
    • Developmental determinants of sensitivity and resistance to stress
    • Levine S. Developmental determinants of sensitivity and resistance to stress. Psychoneuroendocrinology 2005, 30:939-946.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 939-946
    • Levine, S.1
  • 26
    • 0033926720 scopus 로고    scopus 로고
    • Maternal care, hippocampal synaptogenesis and cognitive development in rats
    • Liu D., Diorio J., Day J.C., Francis D.D., Meaney M.J. Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nat Neurosci 2000, 3:799-806.
    • (2000) Nat Neurosci , vol.3 , pp. 799-806
    • Liu, D.1    Diorio, J.2    Day, J.C.3    Francis, D.D.4    Meaney, M.J.5
  • 28
    • 51349101130 scopus 로고    scopus 로고
    • Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system
    • Llorente R., Llorente-Berzal A., Petrosino S., Marco E.M., Guaza C., Prada C., Lopez-Gallardo M., Di Marzo V., Viveros M.P. Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system. Dev Neurobiol 2008, 68:1334-1347.
    • (2008) Dev Neurobiol , vol.68 , pp. 1334-1347
    • Llorente, R.1    Llorente-Berzal, A.2    Petrosino, S.3    Marco, E.M.4    Guaza, C.5    Prada, C.6    Lopez-Gallardo, M.7    Di Marzo, V.8    Viveros, M.P.9
  • 29
    • 84857132399 scopus 로고    scopus 로고
    • Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, cb1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion
    • López-Gallardo M., López-Rodríguez A.B., Llorente-Berzal A., Rotllant D., Mackie K., Armario A., Nadal R., Viveros M.P. Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, cb1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion. Neuroscience 2008, 204:90-103.
    • (2008) Neuroscience , vol.204 , pp. 90-103
    • López-Gallardo, M.1    López-Rodríguez, A.B.2    Llorente-Berzal, A.3    Rotllant, D.4    Mackie, K.5    Armario, A.6    Nadal, R.7    Viveros, M.P.8
  • 30
    • 54249101336 scopus 로고    scopus 로고
    • Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats
    • Malinen H., Hyytia P. Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats. Alcohol Clin Exp Res 2008, 32:1976-1983.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 1976-1983
    • Malinen, H.1    Hyytia, P.2
  • 31
    • 0033452718 scopus 로고    scopus 로고
    • Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
    • Marsicano G., Lutz B. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur J Neurosci 1999, 11:4213-4225.
    • (1999) Eur J Neurosci , vol.11 , pp. 4213-4225
    • Marsicano, G.1    Lutz, B.2
  • 32
    • 84863429122 scopus 로고    scopus 로고
    • The endocannabinoid system modulates the valence of the emotion associated to food ingestion
    • Méndez-Díaz M., et al. The endocannabinoid system modulates the valence of the emotion associated to food ingestion. Addict Biol. 2012, 17:725-735.
    • (2012) Addict Biol. , vol.17 , pp. 725-735
    • Méndez-Díaz, M.1
  • 34
    • 0028149213 scopus 로고
    • Ethanol inhibits glutamaterigic neurotransmission in nucleus accumbens neurons by multiple mechanisms
    • Nie Z., Madamba S.G., Siggins G.R. Ethanol inhibits glutamaterigic neurotransmission in nucleus accumbens neurons by multiple mechanisms. J Pharmacol Exp Ther 1994, 271:1566-1573.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 1566-1573
    • Nie, Z.1    Madamba, S.G.2    Siggins, G.R.3
  • 35
    • 53549118886 scopus 로고    scopus 로고
    • Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption
    • Onaivi E.S., Carpio O., Ishiguro H., Schanz N., Uhl G.R., Benno R. Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. Ann N Y Acad Sci 2008, 1139:426-433.
    • (2008) Ann N Y Acad Sci , vol.1139 , pp. 426-433
    • Onaivi, E.S.1    Carpio, O.2    Ishiguro, H.3    Schanz, N.4    Uhl, G.R.5    Benno, R.6
  • 36
    • 9444277292 scopus 로고    scopus 로고
    • Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis
    • Patel S., Roelke C.T., Rademacher D.J., Cullinan W.E., Hillard C.J. Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. Endocrinology 2004, 145:5431-5438.
    • (2004) Endocrinology , vol.145 , pp. 5431-5438
    • Patel, S.1    Roelke, C.T.2    Rademacher, D.J.3    Cullinan, W.E.4    Hillard, C.J.5
  • 39
    • 1642310341 scopus 로고    scopus 로고
    • Long-term effects of maternal separation on ethanol intake and brain opioid and dopamine receptors in male Wistar rats
    • Ploj K., Roman E., Nylander I. Long-term effects of maternal separation on ethanol intake and brain opioid and dopamine receptors in male Wistar rats. Neuroscience 2003, 121:787-799.
    • (2003) Neuroscience , vol.121 , pp. 787-799
    • Ploj, K.1    Roman, E.2    Nylander, I.3
  • 40
    • 0027195888 scopus 로고
    • Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats
    • Plotsky P.M., Meaney M.J. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Brain Res Mol Brain Res 1993, 18:195-200.
    • (1993) Brain Res Mol Brain Res , vol.18 , pp. 195-200
    • Plotsky, P.M.1    Meaney, M.J.2
  • 41
    • 0036024263 scopus 로고    scopus 로고
    • Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus
    • Roceri M., Hendriks W., Racagni G., Ellenbroek B.A., Riva M.A. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol Psychiatry 2002, 7:609-616.
    • (2002) Mol Psychiatry , vol.7 , pp. 609-616
    • Roceri, M.1    Hendriks, W.2    Racagni, G.3    Ellenbroek, B.A.4    Riva, M.A.5
  • 42
    • 17444418262 scopus 로고    scopus 로고
    • Short and prolonged periods of maternal separation and voluntary ethanol intake in male and female ethanol-preferring AA and ethanol-avoiding ANA rats
    • Roman E., Gustafsson L., Hyyti P., Nylander I. Short and prolonged periods of maternal separation and voluntary ethanol intake in male and female ethanol-preferring AA and ethanol-avoiding ANA rats. Alcohol Clin Exp Res 2005, 29:591-601.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 591-601
    • Roman, E.1    Gustafsson, L.2    Hyyti, P.3    Nylander, I.4
  • 43
    • 27544466313 scopus 로고    scopus 로고
    • The impact of emotional stress early in life on adult voluntary ethanol intake-results of maternal separation in rats
    • Roman E., Nylander I. The impact of emotional stress early in life on adult voluntary ethanol intake-results of maternal separation in rats. Stress Int J Biol Stress 2005, 8:157-174.
    • (2005) Stress Int J Biol Stress , vol.8 , pp. 157-174
    • Roman, E.1    Nylander, I.2
  • 44
    • 0037123855 scopus 로고    scopus 로고
    • Blockade by the cannabinoid CB1 receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats
    • Serra S., Brunettia G., Pani M., Vacca G., Carai M.A.M., Gessa G.L., Colombo G. Blockade by the cannabinoid CB1 receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats. Eur J Pharmacol 2002, 443:95-97.
    • (2002) Eur J Pharmacol , vol.443 , pp. 95-97
    • Serra, S.1    Brunettia, G.2    Pani, M.3    Vacca, G.4    Carai, M.A.M.5    Gessa, G.L.6    Colombo, G.7
  • 45
    • 34547574943 scopus 로고    scopus 로고
    • Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus
    • Soria-Gomez E., Matias I., Rueda-Orozco P.E., Cisneros M., Petrosino S., Navarro L., Di Marzo V., Prospero-Garcia O. Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. B J Pharmacol 2007, 151:1109-1116.
    • (2007) B J Pharmacol , vol.151 , pp. 1109-1116
    • Soria-Gomez, E.1    Matias, I.2    Rueda-Orozco, P.E.3    Cisneros, M.4    Petrosino, S.5    Navarro, L.6    Di Marzo, V.7    Prospero-Garcia, O.8
  • 46
    • 77953288431 scopus 로고    scopus 로고
    • Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration
    • Sperling R.E., Gomes S.M., Sypek E.I., Carey A.N., McLaughlin J.P. Endogenous kappa-opioid mediation of stress-induced potentiation of ethanol-conditioned place preference and self-administration. Psychopharmacology 2010, 210:199-209.
    • (2010) Psychopharmacology , vol.210 , pp. 199-209
    • Sperling, R.E.1    Gomes, S.M.2    Sypek, E.I.3    Carey, A.N.4    McLaughlin, J.P.5
  • 47
    • 49049111067 scopus 로고    scopus 로고
    • Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses
    • Steiner M.A., Marsicano G., Wotjak C.T., Lutz B. Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses. Psychoneuroendocrinology 2008, 33:1165-1170.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 1165-1170
    • Steiner, M.A.1    Marsicano, G.2    Wotjak, C.T.3    Lutz, B.4
  • 48
    • 67649654149 scopus 로고    scopus 로고
    • Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats
    • Suárez J., Llorente R., Romero-Zerbo S.Y., Mateos B., Bermúdez-Silva F.J., de Fonseca F.R., Viveros M.P. Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats. Hippocampus 2009, 19:623-632.
    • (2009) Hippocampus , vol.19 , pp. 623-632
    • Suárez, J.1    Llorente, R.2    Romero-Zerbo, S.Y.3    Mateos, B.4    Bermúdez-Silva, F.J.5    de Fonseca, F.R.6    Viveros, M.P.7
  • 49
    • 44349149240 scopus 로고    scopus 로고
    • Ethanol enhances GABAergic transmission onto dopamine neurons in the ventral tegmental area of the rat
    • Theile J.W., Morikawa H., Gonzales R.A., Morrisett R.A. Ethanol enhances GABAergic transmission onto dopamine neurons in the ventral tegmental area of the rat. Alcohol Clin Exp Res 2008, 32:1040-1048.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 1040-1048
    • Theile, J.W.1    Morikawa, H.2    Gonzales, R.A.3    Morrisett, R.A.4
  • 51
    • 73249142471 scopus 로고    scopus 로고
    • Shaping adult phenotypes through early life environments
    • Weaver I.C. Shaping adult phenotypes through early life environments. Birth Defects Res C Embryo Today 2009, 87:314-326.
    • (2009) Birth Defects Res C Embryo Today , vol.87 , pp. 314-326
    • Weaver, I.C.1
  • 53
    • 41149163856 scopus 로고    scopus 로고
    • Ethanol selectively attenuates NMDAR-mediated synaptic transmission in the prefrontal cortex
    • Weitlauf C., Woodward J.J. Ethanol selectively attenuates NMDAR-mediated synaptic transmission in the prefrontal cortex. Alcohol Clin Exp Res 2008, 32:690-698.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 690-698
    • Weitlauf, C.1    Woodward, J.J.2
  • 54
    • 84866510913 scopus 로고    scopus 로고
    • WHO, Global status report on alcohol and health. In: WHO library cataloguing.
    • WHO (2011) Global status report on alcohol and health. In: WHO library cataloguing.
    • (2011)


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