Oleanolic acid potentiates the antitumor activity of 5-fluorouracil in pancreatic cancer cells

Oncology Reports

Volumn 28, Issue 4, 2012, Pages 1339-1345

  Wei, Jianteng ^a,c   Liu, Haizhou ^a   Liu, Ming ^a   Wu, Ning ^a   Zhao, Jin ^a,c   Xiao, Lin ^a,c   Han, Lijun ^a   Chu, Edward ^d   Lin, Xiukun ^a,b  

^a INSTITUTE OF OCEANOLOGY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

5 fluorouracil; Apoptosis; Oleanolic acid; Pancreatic cancer cells; Synergism

Indexed keywords

CASPASE 3; CATHEPSIN D; CYTOCHROME C; FLUOROURACIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OLEANOLIC ACID; PROTEIN BAX; PROTEIN BCL 2; SURVIVIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CATHEPSIN D; CELL PROLIFERATION; CYTOCHROMES C; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTRACELLULAR MEMBRANES; LYSOSOMES; NF-KAPPA B; OLEANOLIC ACID; PANCREATIC NEOPLASMS; PERMEABILITY; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 84866458797     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1921     Document Type: Article

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